All Nature journals allow posting on biorxiv en.wikipedia.org/wiki/List_of...

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

Is there a circuit that can anticipate future energy needs?

A hypothalamic circuit for anticipating future changes in energy balance. https://www.biorxiv.org/content/10.1101/2025.09.27.678865v1

Super grateful to Brad for all the support, to @walkersamuelj.bsky.social for introducing me to the wonderful worlds of systems neuroscience and feeding regulation, to @amdouglass.bsky.social for always pointing me in the right direction, and all the other co-authors for their contributions!

Great job! Beautiful paper, many congratulations 👏🏻

Really excited to share my co-first publication together with @walkersamuelj.bsky.social from the Lowell lab @bidmcreseach.bsky.social @harvardmed.bsky.social!

A one-time gene therapy can markedly slow the progression of Huntington’s disease, potentially paving the way for the first ever treatment to alter the course of this rare, inherited brain disorder.

go.nature.com/4gLO6Wz

www.linkedin.com/posts/kathle... H1B visa holders and new applicants, please read. My understanding is that universities and non for profit institutions will be exempt, when hiring scientists with doctorate degrees or physicians.

NIH issued 2,439 notices of award after 9/13/2025. Including 128 new R01. Sixteen new R01 from NIAAA (38 total Type 1 from NIAAA).

www.linkedin.com/posts/kathle... H1B visa holders and new applicants, please read. My understanding is that universities and non for profit institutions will be exempt, when hiring scientists with doctorate degrees or physicians.

The latest news states that this doesn’t apply to current H1B visa holders, even if they’re out of the country. It only applies to new applicants that are out of the country? This is my understanding. Not clear if J1 visa holders that have secured a faculty position will be subjected to the 100k fee

The R21 have been MYF already. Nothing new here….

This is very good news.

BUT, as we saw this year when NIH was operating under a flat budget, Trump and Russell Vought can effectively destroy NIH even if Congress holds the budget flat.

To stop Vought and make sure NIH can function, Congress must go much further than “no cuts to budget.”

1/

The House discretionary budget bill is now out for FY26, including a proposed *slight boost* in NIH funding & many other components that will take time to unpack.

Bill text:
appropriations.house.gov/sites/evo-su...

A few key points including IDC analysis in a provisional 🧵

Addgene can package AAV vectors on request — but what are AAV vectors, and why should you use them? Whether you’re new to AAV or refining your knowledge, our newly updated AAV guide will help you answer your questions!

Agree, difficult times for so many of us 🙏🏻

I also think many at NIH are doing the best they can under the present circumstances 🙏🏻

I agree, the process of issuing NOA & getting these out the door is taking much longer. My approach is to stay the course & keep submitting the best grants I can. Good luck to us all! Also, it’s a time to collaborate more/include co-investigators with effort. Together we stand a better chance.

Evolution is more like a tinkerer than an engineer. New things happen not by perfect engineering but by working with what's already available and repurposing existing objects through recombinations and modifications. This is a classic lesson for any kind of innovation, including that of new ideas..