Lightnews — Scholar-powered news

Reposted by Lucien Hinderling

Jonas Wietek @jwietek.bsky.social · 9h

www.nature.com/articles/s41...

Emiliani Lab

High-throughput synaptic connectivity mapping using in vivo two-photon holographic optogenetics and compressive sensing - Nature Neuroscience

Using two-photon optogenetics, electrical recordings and sparse signal reconstruction, the authors demonstrate in vivo synaptic connectivity mapping in the mouse visual cortex.

www.nature.com

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Reposted by Lucien Hinderling

bioRxiv Biophysics @biorxiv-biophys.bsky.social · 4d

Low-Cost 3D Printed Optics for Super-Resolution Multifocal Structured Illumination Microscopy https://www.biorxiv.org/content/10.1101/2025.10.09.680962v1

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Reposted by Lucien Hinderling

Max Fürst @maxfus.bsky.social · 10d

Un-frigging-believable. I have waited for something like this for so long!

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Reposted by Lucien Hinderling

Sebi @sebi06.bsky.social · 19d

Hi Fans of Smart Microscopy,

Are you ready to automate your next large scale microscopy experiment and work smarter, not harder?

Join us for the Smart Microscopy workshop organized by EPFL Bio-Imaging Platform (Lausanne) and @zeiss-microscopy.bsky.social

www.zeiss.ch/mikroskopie/...

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Lucien Hinderling @lhinderling.bsky.social · 14d

... and 7 academic labs! @olivierpertz.bsky.social @toettch.bsky.social @hannah-superres.bsky.social @alfredorates.bsky.social
Your implementation is missing? Want to join our monthly meetings on smart microscopy approaches? Contact us & find out more on
smartmicroscopy.github.io

Smart Microscopy Working Group — Smart Microscopy Working Group's Website

smartmicroscopy.github.io

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Lucien Hinderling @lhinderling.bsky.social · 14d

Now featuring contributions from 6 microscope brands (Inscoper, Zeiss, openUC2, Luxendo, Cytely, Nikon)
@inscoper.bsky.social @zeiss-microscopy.bsky.social @openuc2.bsky.social @healthcare.nikon.com ...

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Lucien Hinderling @lhinderling.bsky.social · 14d

Want to get started with smart microscopy? 🧠🔬
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...

More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...

screenshots of some of the sample implementations

Screenshot of smartmicroscopy.github.io/implementations.html, showing an overview of collected implementation examples

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Lucien Hinderling @lhinderling.bsky.social · 16d

seems to also contain a lot of useful IO/processing/filtering functions i find myself reimplementing again and again across projects
mannlabs.github.io/scPortrait/i...

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Reposted by Lucien Hinderling

Christophe 🔬 L @christlet.bsky.social · 19d

#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data

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Reposted by Lucien Hinderling

Eugene Katrukha 🇺🇦 @ekatrukha.bsky.social · 21d

New release of #BigTrace plugin is out. Together with @aafkegros.bsky.social from Simone Köhler group we added a fully automatic tracing mode. + more macro functions and bug fixes github.com/ekatrukha/Bi...

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Reposted by Lucien Hinderling

kuba sędziński @kuba-sedzinski.bsky.social · 23d

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

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Reposted by Lucien Hinderling

Robert Grosse @ grosselab @grosselab.bsky.social · 23d

we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social

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Reposted by Lucien Hinderling

Hao Yin @haoyin.bsky.social · 24d

Fibroblast co-culture shapes Microvascular network on a chip

HUVEC/human adult lung fibroblast (5/1) in fibrin hydrogel➡️a sustained, arborized & perfusable microvasculature

Gravity-driven flow prunes the network 🤓

Void-based microvascular morphometry

bioRxiv 2025
www.biorxiv.org/content/10.1...

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Reposted by Lucien Hinderling

Daniel J. Cohen (Princeton) @djcohen.bsky.social · 27d

SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N

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Reposted by Lucien Hinderling

Chenxin Li, PhD @chenxinli2.bsky.social · Sep 14

My most successful outreach effort by far is the "Friends Don't Let Friends Made Bad Graphs" repository. It has 6.8 bookmarks on GitHub. That's just people with a GitHub account, not counting those who have used it but don't have a GitHub account.

github.com/cxli233/Frie...

GitHub - cxli233/FriendsDontLetFriends: Friends don't let friends make certain types of data visualization - What are they and why are they bad.

Friends don't let friends make certain types of data visualization - What are they and why are they bad. - GitHub - cxli233/FriendsDontLetFriends: Friends don't let friends make certain ty...

github.com

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Reposted by Lucien Hinderling

Joachim Goedhart @joachimgoedhart.bsky.social · Sep 11

We have updated our preprint "A green lifetime biosensor for calcium that remains bright over its full dynamic range" with some new data - including this photo showing the difference in color for the Turquoise and Green lifetime probe. www.biorxiv.org/content/10.1...

Figure 1. The excitation and emission peaks of G-Ca-FLITS are red-shifted relative to Tq-Ca-FLITS. (A) The
excitation and emission spectra show in lighter lines the calcium-free state (10 mM EGTA) and the darker
lines the calcium-bound state (39 μM free Ca2+). The Tq-Ca-FLITS is shown as a reference and was reported
before (van der Linden et al., 2021). Spectra are normalized to the maximum of the calcium-free state for
G-Ca-FLITS. (B) The photo shows the fluorescence from tubes of purified biosensors when excited with UV
(312 nm).

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Reposted by Lucien Hinderling

eurobioimaging.bsky.social @eurobioimaging.bsky.social · Sep 11

Join our workshop to explore remote user access experiences at our Finnish Advanced Microscopy Node and at the Multimodal Molecular Imaging (MMMI) Italian Node. Facility experts & users will share their experiences!
🗓️ September 23 at 15:00 CEST
Register 🔽
www.eurobioimaging.eu/events/user-...

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Reposted by Lucien Hinderling

tabdanov.bsky.social @tabdanov.bsky.social · Sep 9

Just posted (bioRxiv): A novel #mechanobiology model revealing how #immune #Tcells combine a #nucleus as a #piston, an #uropod, and #microenvironment to power #amoeboid #cellmigration in #cellconfinement via a hydraulic cell engine. #CellBiophysics #ImmuneMigration
www.biorxiv.org/content/10.1...

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Reposted by Lucien Hinderling

jofmicroscopy.bsky.social @jofmicroscopy.bsky.social · Sep 10

📣 Call for papers: "Taking the Stage: The Future of Microscopy"

The Journal has launched an open call for papers for an exciting new special issue which will feature submissions by Early Career Researchers. The issue will be guest edited by Katherine Paine, Myfanwy Adams and Colum O'Leary.

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Reposted by Lucien Hinderling

catdefence.bsky.social @catdefence.bsky.social · Aug 30

An Open Source Motorized XYZ Micro-Manipulator - Affordable sub µm Motion Control
www.youtube.com/watch?v=MgQb...

An Open Source Motorized XYZ Micro-Manipulator - Affordable sub µm Motion Control

YouTube video by Diffraction Limited

www.youtube.com

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Reposted by Lucien Hinderling

Jonatan Alvelid @jonatanalvelid.bsky.social · Sep 2

Excited to share my postdoc work from the Eggeling lab in Jena (@leibnizipht.bsky.social, #FSUJena, #KTHuniversity) on bringing smart microscopy to super-resolution MINFLUX: event-triggered MINFLUX microscopy.

Demonstrative schematics and example timeline of event-triggered MINFLUX microscopy.

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Reposted by Lucien Hinderling

epithelial mechanics fan club @epimechfc.bsky.social · Aug 31

Are different cell types like oil and water? Over a century ago, researchers found that dissociated sponges and embryonic tissues can self-assemble into functional structures. Join me, @benswedlund.bsky.social to explore the differential adhesion hypothesis & its applications in tissue engineering!

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Reposted by Lucien Hinderling

Ben Engel @cellarchlab.com · Aug 26

BIG NEWS!! We will be hiring a new professor with 25 years of endowed funding at the @biozentrum.unibas.ch @unibas.ch, focused on using biophysics and structural biology to explore climate-related fundamental science topics. Come start an innovative research cluster with us! 🧪🔬🧶🧬🌾🌍

University of Basel @unibas.ch · Aug 26

The University of Basel is setting up a new endowed professorship at the @biozentrum to make fundamental discoveries at the interface between biophysics and climate-relevant environmental biology. This will be made possible by the Georg H. Endress Foundation.

New endowed professorship strengthens climate research at the University of Basel

The University of Basel is setting up a new endowed professorship at the Biozentrum to make fundamental discoveries at the interface between b...

www.unibas.ch

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Reposted by Lucien Hinderling

Joel Lüthi @joelluethi.bsky.social · Aug 25

We're happy to announce the 2025 International OME-NGFF workshop 🎉

📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025

📍 Location: Zurich, Switzerland

Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...

#bioimaging #openscience #OMENGFF #OMEZarr

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Visual of segmented human induced pluripotent stem cells with the key workshop dates: Symposium on November 10-11, Hackathon on November 12-14th in Zurich Switzerland

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Reposted by Lucien Hinderling

Virginie Uhlmann @virginieuhlmann.bsky.social · Aug 25

Once is an exception, twice is a trend, thrice is a tradition!

Save the date for our now-traditional annual OME-NGFF extravaganza in Zurich!

Whether you’ve just heard about OME-NGFF and are curious to learn more or if you are working with it every day, there is something for everyone this year!

Joel Lüthi @joelluethi.bsky.social · Aug 25

We're happy to announce the 2025 International OME-NGFF workshop 🎉

📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025

📍 Location: Zurich, Switzerland

Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...

#bioimaging #openscience #OMENGFF #OMEZarr

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