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Julia Eckert

@juliaeckert.bsky.social

1.8K followers 430 following 82 posts

@dfg.de Walter Benjamin Fellow & Postdoctoral Researcher @yap-lab.bsky.social | Co-organizer @epimechfc.bsky.social | Mechanobiology - Cell & Tissue Mechanics - Soft Matter Physics - Image Analysis 👉 https://julia-eckert.github.io

julia-eckert.github.io

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Julia Eckert @juliaeckert.bsky.social · Aug 15

Now published in @natcomms.nature.com! 🥳

👉 rdcu.be/eATn3

We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.

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Daniel J. Cohen (Princeton) @djcohen.bsky.social · 12d

So: can a cell hold hands with itself…and do we care? YES and YES! Read on to learn WHY, HOW, and what this has to do with…PARIS (and tree-hugging)? Swansong of Dr. Anamika; Hannah Kim on drums; and fantastic undergrads (Margaret/Lauren) ! 1/n
advanced.onlinelibrary.wiley.com/doi/10.1002/...

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epithelial mechanics fan club @epimechfc.bsky.social · 20h

1/ 🐣⚒️ To study mechanics, we need to apply prescribed forces - how can we do that in living tissues? I am @eigenp.bsky.social and in this thread I'll highlight our new approach for applying tension on epithelial tissues in vivo!

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Science News @scinews.bsky.social · 3d

How to develop good research questions

www.nature.com/articles/s41...

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Oliver Jensen @oeskildjensen.bsky.social · 5d

Harmonic fields and the mechanical response of a cellular monolayer to ablation arxiv.org/abs/2510.05193

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@NicoliLab @nicolilab.bsky.social · 2d

So excited to announce lab alumni Dr. Helen Mengze He and Liana Boraas work at @yalecvrc.bsky.social in collaboration with the Kaelyn Sumigray lab @yaleschoolofmed.bsky.social is published today in @natcomms.nature.com and highlighted in Yale News! medicine.yale.edu/news-article...

Unlocking the Skin’s Natural Healing Power

Researchers show that embryonic skin stem cells rely on a specialized mechanism to resist injury. The findings could lead to new strategies for repairing wounds

medicine.yale.edu

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Reposted by Julia Eckert

natalieadye.bsky.social @natalieadye.bsky.social · 2d

How are tissue folds stabilized during animal organ development? Our latest preprint helps to answer this question, using the fruit fly wing disc as a model doi.org/10.1101/2025.... @poldresden.bsky.social @mpipks.bsky.social @dfg.de @janafuhrmann.bsky.social @vicioms.bsky.social @mbisg.bsky.social

Apical extracellular matrix regulates fold morphogenesis in the Drosophila wing disc

Tissue folding is a fundamental process occurring in animal organ development. Here, we study the progression of fold shape and the underlying mechanics in the development of the Drosophila wing disc....

doi.org

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Climate, Ecology, War & More by Dr. Glen Barry, BigEarthData.ai @bigearthdata.bsky.social · 4d

Cell tracking with accurate error prediction
->Nature | More from Lil' Dr Glen at BigEarthData.ai

Cell tracking with accurate error prediction

Mouse intestinal organoids with an H2B-mCherry reporter were used, gifted by N. Sachs and J. Beumer (group of H. Clevers, Hubrecht Institute). Organoids were grown embedded in membrane extract (BME, Trevigen) in medium consisting of murine recombinant epidermal growth factor...

www.nature.com

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epithelial mechanics fan club @epimechfc.bsky.social · 3d

Charras, G. and Yap, A. S. (2018). Tensile forces and mechanotransduction at cell–cell junctions. Current Biology, #EpithelialMechanicsReview www.cell.com/current-biol...

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Levayer Lab @levayerr.bsky.social · 3d

Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal
www.sciencedirect.com/science/arti...

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Miki Ebisuya @ebisuyamiki.bsky.social · 4d

New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...

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Denis Krndija @deniskrndija.bsky.social · 4d

Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11)
🔗 www.biorxiv.org/content/10.1...

Robust pan-junctional reinforcement preserves the gut epithelial barrier under mechanical stress

Epithelia are specialized tissue barriers that safeguard the organism's internal milieu from the hostile external environment, a function critically dependent on intercellular junctions. In the colon,...

www.biorxiv.org

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Nature Reviews Physics @natrevphys.nature.com · 5d

Mechanobiology across timescales

A Review by Bo Cheng, Moxiao Li, Min Lin, Hui Guo & Feng Xu ⚛️🧪
www.nature.com/articles/s42...

Mechanobiology across timescales - Nature Reviews Physics

This Review explores how cells sense and respond to mechanical signals across timescales. By integrating mechanosensing at membranes, mechanotransduction in the cytoplasm, and nuclear reprogramming, it reveals a role of temporal dynamics in tissue development and disease.

www.nature.com

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Nature @nature.com · 5d

John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale

go.nature.com/3WnEUhE

Groundbreaking quantum-tunnelling experiments win physics Nobel

John Clarke, Michel Devoret and John Martinis discovered quantum physics on a macroscopic scale, paving the way for quantum computing.

go.nature.com

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Sam Aytekin @samaytekin.bsky.social · 6d

Garcia Lab did it again! Such a fantastic read if you are interested in FAs mechanics and biology. Congratulations to @garcialabgt.bsky.social

Mechanochemical waves in focal adhesions during cell migration

Traction force and FAK signaling exhibit oscillatory temporal coupling in adhesive structures.

www.science.org

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Reposted by Julia Eckert

Juanma García-Arcos @juanmagararc.bsky.social · 7d

🚨 New preprint out!
“Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM” with Tithi Mandal and @rouxlab.bsky.social
We benchmark and describe step-by-step Flipper-TR FLIM measurements across different set-ups and and strategies.

www.biorxiv.org/content/10.1...

Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM

Flipper-TR is a membrane dye sensitive to lipid packing widely used to probe membrane tension in live cells via fluorescence lifetime imaging microscopy (FLIM). However, no consensus currently exists ...

www.biorxiv.org

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epithelial mechanics fan club @epimechfc.bsky.social · 9d

How do dynamic forces influence symmetry-breaking in embryonic development?

Hi, I’m @dr-rajendra-s-negi.bsky.social & in this thread, I’d like to introduce some aspects of the interdisciplinary research on tissue dynamics.

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Maik Bischoff @maikbischoff.bsky.social · 10d

My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls

Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨

🔗 www.nikonsmallworld.com/galleries/20...

#NikonSmallWorld #Microscopy #ScienceArt

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Julia Eckert @juliaeckert.bsky.social · 9d

😍 nematic order 😍 can I analyze it?

Reposted by Julia Eckert

James Briscoe @jamesbriscoe.bsky.social · 9d

Mechanical constraints disrupt gastruloid polarisation without changing gene expression - uncouples morphogenesis & patterning

Gregor & co use tunable hydrogels to show cell motility, not gene expression, drives axis formation in gastruloids

journals.biologists.com/dev/article/...

Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids

Highlighted Article: A bioinert confinement system enables dissection of how stiffness and timing shape gastruloid development, revealing uncoupling between polarization and transcriptional programs.

journals.biologists.com

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arXiv cond-mat.soft Soft Condensed Matter @condmatsoft-bot.bsky.social · 10d

Lea Happel, Griseldis Oberschelp, Anneli Richter, Gwenda Roselene Rode, Valeriia Grudtsyna, Amin Doostmohammadi, Axel Voigt: A spectrum of p-atic symmetries and defects in confluent epithelia https://arxiv.org/abs/2510.02160 https://arxiv.org/pdf/2510.02160 https://arxiv.org/html/2510.02160

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Julia Eckert @juliaeckert.bsky.social · 10d

Excited to participate in the Scientific Art Contest at #CellMech2025.

Julia Eckert @juliaeckert.bsky.social · 10d

@epimechfc.bsky.social discussion with @dedenonmathieu.bsky.social at #CellMech2025 :)

CellMech2025 @cellmech2025.bsky.social · 10d

Coffee break in full swing at #cellmech2025 —fueling up for the next session!

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myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 10d

www.nature.com/articles/s41...

Dynamic rigidity changes enable rapid cell migration on soft substrates - Nature Communications

Cells struggle to migrate on soft substrates, which don’t provide enough traction. Here, the authors show that rapid, cyclic changes in substrate rigidity allow cells to overcome this limitation and move quickly.

www.nature.com

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Kate Cavanaugh @katecavanaugh.bsky.social · 11d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

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Theory of Living Matter Group @tlmcambridge.bsky.social · 11d

🚨New academic year calls for a new lineup of speakers. ✍️Sign up to our mailing list to hear these wonderful array of speakers this term. Please reshare among your networks 📩 lists.cam.ac.uk/sympa/subscr...

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