The Journal of Physiology
@jphysiol.bsky.social
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The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
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jphysiol.bsky.social
Le Zhao et al. revisit brown #adipose tissue whitening and examine the physiological mechanisms and #pathophysiological consequences 🔎 📖

🔗 Read the #TopicalReview here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Geneviève J. DesOrmeaux of maastrichtu.bsky.social et al. present this #JournalClub focusing on the work of Luk et al. (2025), highlighting that strength training while #dehydrated causes excessive oxidative stress in skeletal muscle ✍️ 🫗

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
This #Perspective by Audrey P. Stegman & Christopher M. Depner of utah.edu examines nocturnal blood pressure decline and fall risk in older adults and the work of Thosar & Shea (2025) 💭

🔗 Access it here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Michelle Sanchez-Rivera et al. investigated atypical delayed paired-pulse depression at an identified #synapse 🧠🔎

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Liam H. Foulger et al. observed that learning to stand with delays alters #sensorimotor control but does not cause instability when returning to natural balance 🧠 ⚖️

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Recent #Research by Yucheng Xiao et al. observed that contusive spinal cord injury causes Nav1.8 dysfunction to upregulate small sensory #neuron excitability 🧠 ⚡

📜 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Recent #Research by Trent Meehan et al. observed that #danicamtiv increases #cardiac mechanical efficiency 🫀 💊

📜 Read the article: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Andrew G. Horn of utah.edu et al. offer this #Perspective on the work of Lance et al. (2025) into #diaphragm blood flow 💭 🫁

Read it here: 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Xiaolong Gao offers this #Perspective on the work of Závoti & Csanády (2025) into #molecular and pharmacological evaluation of rare, cystic fibrosis-causing missense mutations of the #CFTR channel 💭

🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
In this recent study, Morten Hostrup et al. found that #clenbuterol induces lean mass and muscle protein accretion, but attenuates #cardiorespiratory fitness and desensitizes muscle β2-adrenergic signalling 💉🚴

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Gabriel Calheiros Antunes et al. performed this sex-dependent study and observed that time-restricted feeding combined with exercise improves hepatic and glycaemic #metabolism in obese mice⏰ 🍽️

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
In this study, Hong Li et al. investigated modulation of #neurometabolites in sensory processing brain areas during motor learning ⚙️ 🧠

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
This study by Emmanuel V. Araujo et al. observed that #oxytocinergic signalling in the #respiratory parafacial region increases the activity of chemosensitive neurons and respiratory output 🫁 ⚙️

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
#Research by Katie Greenin-Whitehead et al. finds that ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells 🔬 🧠

🔗 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Mohammadreza Kariman of medunigraz.at et al. undertook computational modelling of the impact of anatomical changes on ECGs in left ventricular #hypertrophy 🫀 💻

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
In this study, Olivér Závoti & László Csanády performed #molecular and pharmacological evaluation of rare, cystic fibrosis-causing missense mutations of the #CFTR channel 🔬🧬

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Brian Lam of yorkuniversity.bsky.social et al. observed that #endurance training increases a ubiquitylated form of #histone H3 in the skeletal muscle, supporting Notch1 upregulation in an MDM2-dependent manner 🏃 🧬

📜 🔗 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Megan L. Lance et al. investigated the #hyperaemic and #metaboreflex response of the #diaphragm during fatiguing diaphragmatic work in humans 🫁 📝

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
Recent #Research by Jadwiga N. Bilchak of pennmedicine.bsky.social et al. finds that #KCC2 enhancers normalize reflex responses and improve #locomotor function after chronic spinal cord injury 🧠 ⚙️

📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
In this study, Filip Ježek of charlesuni.cuni.cz et al. performed theoretical analysis of power-law stress relaxation and calcium-dependent passive #mechanics in #cardiac muscle 🫀 ⚙️

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
🎓 EDITOR'S CHOICE🎓

#Research by Saurabh Suhas Thosar & Steven A. Shea of @occhealthsci.bsky.social observes that elderly humans show an impaired blood pressure adaptation to arising from bed during the nighttime.

📜 🔗https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP289266
jphysiol.bsky.social
Paolo Spaiardi et al. found that transient capacitance changes recorded from vestibular type I hair cells are produced by GK,L gating and do not involve #neurotransmitter exocytosis 🧠 💉

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
jphysiol.bsky.social
#Research by Bettina K. M. Firmke of uniregensburg.bsky.social et al. found that #hypoxia-inducible factor-2 stabilization is not sufficient to induce erythropoietin production in deeper medullary #fibroblasts 🔬 📜

🔗 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
jprecmed.bsky.social
📣 CALL FOR PAPERS📣

Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎

Submit by 28 February 2026 ⏰

🔗 For topics and more information:

www.sciencedirect.com/special-issu...