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Journal of Cell Science @jcellsci.bsky.social · 1m

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Read & Publish agreements offer many benefits to researchers including fee-free Open Access publishing in Development, Journal of Cell Science and Journal of Experimental Biology.

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Journal of Cell Science @jcellsci.bsky.social · 1m

Rishika Abrol, Syeda Farhana Afroz, Divya Ramnath and Matthew Sweet find that histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages.
journals.biologists.com/jcs/article/...

Figure showing HDAC7 associates with mitochondrial fission protein DRP1 and drives LPS-inducible fission in macrophages.

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The Company of Biologists @biologists.bsky.social · 4h

1946: The Quarterly Journal of Microscopical Sciences is transferred to the Company. In 1966, QJMS is renamed Journal of Cell Science @jcellsci.bsky.social. Read JCS’s 100-anniversary article collection: bit.ly/46RvL5N

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The Company of Biologists @biologists.bsky.social · 5h

1926: The British Journal of Experimental Biology is transferred to the Company, and in 1930, BJEB is renamed Journal of Experimental Biology @jexpbiol.bsky.social. Read JEB’s 100-anniversary article collection: bit.ly/4nYbzWI

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The Company of Biologists @biologists.bsky.social · 6h

1925: On this date, 100 years ago, The Company of Biologists is founded by George Parker Bidder III. Throughout today, we will be posting some of our key milestones. Read more about the past 100 years at bit.ly/3WnTVA1.

Poster of the 100-year history of The Company of Biologists.

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Journal of Cell Science @jcellsci.bsky.social · 23h

Read more about this research in our ‘First person’ interview with Shu Yao Leong:
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Journal of Cell Science @jcellsci.bsky.social · 23h

Shu Yao Leong, Erik Schäffer @schaefferlab.bsky.social & team @zmbp-tuebingen.bsky.social discover that the tail domain of the kinesin-12 POK2 acts as a versatile interaction hub for microtubules, MAP65-3 & lipids.
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Figure showing that MAP65-3 increases the microtubule binding of the C-terminal domain of POK2.

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Journal of Cell Science @jcellsci.bsky.social · 1d

This article is available under our Read & Publish Open Access initiative.
Researchers can find out about the wide range of benefits, read what researchers are saying and view a list of participating institutions at www.biologists.com/library-hub/...
#OpenAccess #ReadandPublish

Read & Publish for researchers

Read & Publish agreements offer many benefits to researchers including fee-free Open Access publishing in Development, Journal of Cell Science and Journal of Experimental Biology.

www.biologists.com

Journal of Cell Science @jcellsci.bsky.social · 1d

Luis Fernando Rubio-Atonal, Maria Ioannou and colleagues find that glutamate decreases oxidative stress and lipid droplet formation in astrocytes.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...

Figure showing that glutamate increases mitochondrial oxidation of exogenous fatty acids.

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The Company of Biologists @biologists.bsky.social · 1d

We are highlighting Arnoud Sonnenberg, a distinguished cell biologist who served as a @jcellsci.bsky.social Editor for 19 years, as an extraordinary biologist. #100biologists
@asonnenberg.bsky.social

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Journal of Cell Science @jcellsci.bsky.social · 2d

Luis Fernando Rubio-Atonal, Maria Ioannou and colleagues find that glutamate decreases oxidative stress and lipid droplet formation in astrocytes.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...

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Hauke Drechsler @hd-sci.bsky.social · 4d

Now online @jcellsci.bsky.social: in vitro reconstitution work showing that the tail of plant kinesin-12 POK2 interacts with microtubules, MAP65 and anionic lipids that together could mediate it's targeting to and long-time retention at the cell cortex. journals.biologists.com/jcs/article/...

The tail domain of the plant kinesin-12 POK2 is a versatile interaction hub

Summary: In vitro reconstitution experiments reveal that the tail domain of the kinesin-12 POK2 interacts with microtubules, MAP65-3 and lipids as a possible mechanism for division site deposition and...

journals.biologists.com

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Journal of Cell Science @jcellsci.bsky.social · 5d

In their Review, Danielle Buglak, Brian Galletta & Nasser Rusan propose 3 non-mutually exclusive models to describe sperm head–tail linkage crucial for sperm development, each with varying arrangements of nuclear envelope, cytoplasmic & centriole components.

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Models for the NE components involved in HTCA linkage. (A) Model 1: HTCA linkage is KASH-domain protein-dependent, relying on a classical LINC complex between SUN proteins (purple) in the INM and KASH proteins (cyan) in the ONM to mediate the head–tail connection. KASH proteins then interface with cytoplasmic linkers (orange), such as PMFBP1, SEPTIN12 and Yuri, and centriole or PCM proteins (green box). (B) Model 2: HTCA linkage is NPC-dependent, relying on a physical connection between SUN proteins and the NPC (blue), which spans both nuclear membranes. (C) Model 3: HTCA linkage is direct, with SUN proteins occupying the ONM, rather than their canonical position in the INM, or potentially distorting the INM into an unknown configuration. SUN proteins would then be available to directly interact with cytoplasmic and centrosomal proteins. This model presents a significant paradigm shift in the classical topology of SUN-domain proteins in the NE.

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Journal of Cell Science @jcellsci.bsky.social · 5d

It won’t take you years to publish your work in JCS: most articles go from submission to acceptance in under 4 months. We also show a strong commitment at first decision, with over 95% of revisions being accepted. Find out more: journals.biologists.com/jcs/pages/re...
#forscientists
#notforprofit

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Alexis Barr @alexisbarr.bsky.social · 6d

Many of you know, we lost Béla Novák this year. John Tyson, Francis Barr & I tried to capture his wonderful character & great mind so that those that didn't know him can see what a fantastic person he was.

Thanks to @jcellsci.bsky.social for publishing.

journals.biologists.com/jcs/article/...

Béla Novák (1956–2025) – a legacy of scientific discovery and personal charm

In February 2025, we were shocked and deeply saddened to hear about the death of Béla Novák, Professor in Integrative Systems Biology at the University of Oxford, UK, and a beloved grandfather, father...

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Journal of Cell Science @jcellsci.bsky.social · 6d

Edward Jenkins, Clare Latta and Hoang Anh Le @anhhle2702.bsky.social reflect on the major themes and discussion points from The Company of Biologists @biologists.bsky.social Workshop on ‘Immune Cell Interactions in Development, Homeostasis and Immunity’.
journals.biologists.com/jcs/article/...

Screenshot of pdf on 'Immune cell interactions in development and homeostasis and immunity' by Edward Jenkins, Clare Latta and Hoang Anh Le.

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Journal of Cell Science @jcellsci.bsky.social · 7d

Read more about this research in our ‘First person’ interview with Ling Jin: journals.biologists.com/jcs/article/...

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Journal of Cell Science @jcellsci.bsky.social · 7d

Ling Jin, Muchen Liu and Xianrui Cheng report a centrosome-independent, self-organising microtubule aster that exhibits mostly inverted microtubule polarity and recruits cytokinesis signals to its centre.
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#OpenAccess

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Journal of Cell Science @jcellsci.bsky.social · 7d

Also in Issue 18:
- Research Highlights on cell migration, endocytosis & epithelia contractility
- Interview with Guillaume Thibault
- The integrin odyssey
- Essay on immune cell interactions
- Review on surface protein machineries in Gram-negative bacteria
journals.biologists.com/jcs/issue/13...

Volume 138 Issue 18 | Journal of Cell Science | The Company of Biologists

journals.biologists.com

Journal of Cell Science @jcellsci.bsky.social · 7d

Issue 18 is complete

Explore our ToC: journals.biologists.com/jcs/issue/13...

On the cover: macrophages (white) migrating towards a scratch wound in a zebrafish skin explant (α-catenin, magenta). From @errricpeterman.bsky.social @jraslab.bsky.social et al.
journals.biologists.com/jcs/article/...

JCS cover showing skin-resident macrophages migrating to a scratch wound in the epithelial cells (marked with α-catenin-Citrine, magenta) of a zebrafish skin explant.

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Journal of Cell Science @jcellsci.bsky.social · 8d

This article is available under our Read & Publish Open Access initiative.
Researchers can find out about the wide range of benefits, read what researchers are saying and view a list of participating institutions at www.biologists.com/library-hub/...
#OpenAccess #ReadandPublish

Read & Publish for researchers

Read & Publish agreements offer many benefits to researchers including fee-free Open Access publishing in Development, Journal of Cell Science and Journal of Experimental Biology.

www.biologists.com

Journal of Cell Science @jcellsci.bsky.social · 8d

Sagar Joshi, Lance Davidson and team find that supracellular contractility in Xenopus embryo epithelia is regulated by extracellular ATP and the purinergic receptor P2Y2.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
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Journal of Cell Science @jcellsci.bsky.social · 9d

This article is available under our Read & Publish Open Access initiative.
Researchers can find out about the wide range of benefits, read what researchers are saying and view a list of participating institutions at www.biologists.com/library-hub/...
#OpenAccess #ReadandPublish

Read & Publish for researchers

Read & Publish agreements offer many benefits to researchers including fee-free Open Access publishing in Development, Journal of Cell Science and Journal of Experimental Biology.

www.biologists.com

Journal of Cell Science @jcellsci.bsky.social · 9d

Connor Ross, Stefan Hoppler and colleagues find that WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm.
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Figure showing that TCF7 and LEF1 are upregulated in response to WNT activation in human primed pluripotent ES cells.

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Anh Hoang Le, PhD 🏳️‍🌈 @anhhle2702.bsky.social · 12d

An essay that I wrote with 2 of my newly-met colleagues sharing our experiences attending the Immune Cell Interaction workshop in February. I'm not an immunologist by any traditional means so being given an opportunity to branch out is very much appreciated.
journals.biologists.com/jcs/article/...

Immune cell interactions in development, homeostasis and immunity

ABSTRACT. Immune cells play a fundamental role in coordinating physiological processes, from early stage development through to trained host immunity. Hence, an enhanced insight into the dynamic inter...

journals.biologists.com

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