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JAMA Internal Medicine @jamainternalmed.com · 21h

The Editors of JAMA Internal Medicine are excited to invite the scientific community to contribute studies that will help shape the future of AI in medical and health care research, policy, and practice.

Learn more in this Editorial. ja.ma/4qiuxcS

JAMA Internal Medicine article titled "Artificial Intelligence and Clinical Care." It includes a table defining AI, machine learning, Generative AI, and LLM, published online October 13, 2025.

JAMA Internal Medicine @jamainternalmed.com · 21h

"Artificial intelligence, if implemented thoughtfully and equitably, could unlock a more precise understanding of women’s health."

Learn more in this Editorial. ja.ma/47iHuvD

JAMA Internal Medicine editorial: "Women's Health and Artificial Intelligence" by Eve Rittenberg, Cary P. Gross, Melissa Wong, et al. Published online October 13, 2025. Includes link to Author Affiliations and Article Information.

JAMA Internal Medicine @jamainternalmed.com · 21h

A food subsidy led to better blood pressure control than a delivered food box among adults with hypertension and food insecurity. ja.ma/3WxqYlc

A research article titled, "Food Insecurity Interventions to Improve Blood Pressure: The Healthy Food First Factorial Randomized Clinical Trial" published in JAMA Internal Medicine.

JAMA Internal Medicine @jamainternalmed.com · 1d

Only 4 US states comprehensively regulate IV hydration spa governance, prescriber credentials, dispensing, and compounding practices.

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Map of the USA showing state-level policies for intravenous hydration spas. States are shaded or patterned to represent guidelines on dispensing, governance, prescribing, and compounding, with Alaska and Hawaii shown as insets.

JAMA Internal Medicine @jamainternalmed.com · 2d

A centralized, remote bone health service screening model was associated with improving rates of #osteoporosis screening, treatment, and adherence with high diagnostic yield. ja.ma/46RFNW1

Remote Bone Health Service for Osteoporosis Screening in High-Risk Men

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JAMA Internal Medicine @jamainternalmed.com · 3d

50 mg of oral #semaglutide daily was associated with body weight reduction and improved cardiometabolic risk factors in East Asian adults with overweight or #obesity, with or without type 2 #diabetes. ja.ma/4oa9fMy

Oral Semaglutide in an East Asian Population With Overweight or Obesity, With or Without Type 2 Diabetes

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Reposted by JAMA Internal Medicine

JAMA @jama.com · 3d

IV hydration spas promise to cure hangovers and boost immunity.

But with limited oversight and sparse clinical evidence, are the infusions safe?

Are IV Hydration Spas Safe?

This Medical News article discusses new research into the rise of intravenous hydration spas and the perceived benefits and known risks that come with the unproven treatments.

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JAMA Internal Medicine @jamainternalmed.com · 4d

Shorter durations of #antibiotic prophylaxis, including no prophylaxis, appear noninferior to longer durations for preventing mortality in patients with #cirrhosis and upper gastrointestinal bleeding. ja.ma/3IW9sE0

Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis

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JAMA Internal Medicine @jamainternalmed.com · 4d

Only 4 US states comprehensively regulate IV hydration spa governance, prescriber credentials, dispensing, and compounding practices.

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JAMA Internal Medicine @jamainternalmed.com · 6d

Only 4 US states comprehensively regulate IV hydration spa governance, prescriber credentials, dispensing, and compounding practices.

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JAMA Internal Medicine @jamainternalmed.com · 6d

This Teachable Moment describes a patient in their 60s with severe alcohol use disorder and alcohol-induced cirrhosis complicated by ascites who presented with an altered mental status.

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JAMA Internal Medicine article titled, "A Case for Early High-Dose Thiamine—Moving From Reaction to Prevention," by Douglas N. Goldstein, Alan J. Hunter, and Patricio A. Riquelme. Published online: October 6, 2025.

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JAMA Internal Medicine @jamainternalmed.com · 6d

Viewpoint: The Fifth Amendment ensures due process protections for acute medical care of immigration detainees; differential treatment based on custody is not justified.

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JAMA Internal Medicine article titled "Rights of Immigration Detainees to Acute Medical Care" by Lawrence A. Haber, Hans P. Erickson, and Peter L. Markowitz, published online October 6, 2025.

JAMA Internal Medicine @jamainternalmed.com · 7d

Today the JAMA Internal Medicine editorial board met to discuss goals for the journal, which is dedicated to providing innovative and clinically relevant research for the field of internal medicine.

Watch this space for the latest updates.

JAMA Internal Medicine @jamainternalmed.com · 7d

This JAMA Internal Medicine Patient Page describes dense breasts and whether they might lead to higher risk for #BreastCancer.

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Diagram showing dense versus nondense breasts with labeled tissues. Below are mammogram images showing classifications from almost entirely fatty to extremely dense with noted cancer.

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JAMA Internal Medicine @jamainternalmed.com · 7d

Only 4 US states comprehensively regulate IV hydration spa governance, prescriber credentials, dispensing, and compounding practices.

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JAMA Internal Medicine @jamainternalmed.com · 9d

Among medical students with disabilities, 12.4% reported experiencing discrimination, with the highest rates among those with chronic illness, motor or sensory disabilities, and multiple disabilities. ja.ma/4mKkmKT

A JAMA Internal Medicine research letter titled "Prevalence and Sources of Disability-Based Discrimination in a National Sample of Graduating Medical Students" by Mytien Nguyen et al. Published online July 28, 2025.

JAMA Internal Medicine @jamainternalmed.com · 10d

Vancomycin in midline catheters for outpatient therapy was associated with increased risks of bloodstream infections, venous thromboembolism, and device failure compared to other treatments. ja.ma/3WnffFM

Two graphs display cumulative hazard curves for OPAT patients with midline catheters, comparing vancomycin receipt vs. no vancomycin. Graph A shows major device complications, Graph B shows device failure, over 30 days.

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JAMA Internal Medicine @jamainternalmed.com · 11d

Among FDA anticancer drug approvals from 2009 to 2020, only 27 next-in-class drugs had direct randomized clinical trial comparisons with first-in-class drugs. ja.ma/4q79RV8

Network diagram of randomized clinical trials testing anticancer drugs. Categories include small-molecule inhibitors, chemotherapies, monoclonal antibodies, androgen inhibitors, and immunomodulatory agents, with connecting arrows.

JAMA Internal Medicine @jamainternalmed.com · 12d

Between 2020 and 2023, out-of-sequence kidney transplants in the U.S. increased without corresponding reductions in organ discard rates. ja.ma/46wxC11

JAMA Internal Medicine article: Socioeconomic Disparities in Out-of-Sequence Placement of Deceased Donor Kidneys in the US by Sumit Mohan et al. Published July 7, 2025.

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JAMA Internal Medicine @jamainternalmed.com · 13d

💬 @jama.com Perspective: The evaluation of moderate alcohol consumption on health is complex due to known harms of heavy drinking, potential benefits of low consumption, varying evidence quality, and biases.

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A JAMA article titled "The Complexity of Research on Moderate Alcohol Consumption and Health: The Consensus Report From NASEM" by Ned Calonge et al., published online September 30, 2025.

JAMA Internal Medicine @jamainternalmed.com · 14d

PREVENT risk equations identify fewer adults aged 40–59 as aspirin-eligible for primary ASCVD prevention than PCEs.

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Two bar graphs compare eligibility for primary prevention aspirin in US adults aged 40-59. Graph A shows eligibility by risk calculator (PCES vs. PREVENT) across age, sex, race, and comorbidities. Graph B shows adults eligible by PCEs but not PREVENT.

JAMA Internal Medicine @jamainternalmed.com · 14d

Special Communication: Doubling of early-onset cancer incidence since 1992 in US adults <50 reflects increased diagnosis; mortality remains stable or declines.

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The image shows two line graphs comparing cancer diagnoses and mortality from 1990-2025. The first graph shows the incidence of thyroid, colorectal, endometrial, kidney, anal, pancreatic, myeloma and small intestinal cancers. The second graph shows cancer mortality.

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JAMA Internal Medicine @jamainternalmed.com · 16d

The Patient Driven Payment Model was associated with increased coding intensity and Medicare expenditures in skilled nursing facilities, especially for medically complex patients, without affecting rehospitalization or mortality rates. ja.ma/42O774P

Line graph showing changes in coding intensity before and after PDPM implementation. The x-axis is 'Admission date relative to October 2019, d,' and the y-axis is 'Elixhauser Comorbidity Index score'. Lines represent data for Hospitals and SNFs.

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JAMA Internal Medicine @jamainternalmed.com · 17d

This Guide to Statistics and Methods explains how covariate-constrained randomization (CCR) enhances rigor in cluster randomized clinical trials. ja.ma/3ICwGz1

Covariate-Constrained Randomization (CCR) is illustrated. Section A shows all ways to allocate practices across study arms. Section B shows constrained randomization space. Rural (A, B) and Urban (C, D) practices are randomized.

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JAMA Internal Medicine @jamainternalmed.com · 20d

In adults with acute mild to moderate #COVID19, metformin did not shorten recovery time compared to placebo, with similar median times to symptom resolution in both groups. ja.ma/3UWpQHi

Metformin and Time to Sustained Recovery in Adults With COVID-19

This randomized clinical trial examines metformin compared with placebo for symptom resolution during acute infection with SARS-CoV-2.

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