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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 1h

From my WHN Long Cövid Crew‼️

We area busy little engine💪🏻

Misty M ⛰🌻🌳🌺🦋🐝😷 @mistym.bsky.social · 5h

So many of our learned friends have been right about so much.

If only everyone else had bothered to listen.

www.ajpmfocus.org/article/S277...

COVID-19 is “Airborne AIDS”: provocative oversimplification, emerging science, or something in between?

COVID-19 caused by SARS-CoV-2 is often compared to other pandemics for its societal and global health impact, with some commentators drawing parallels to HIV/AIDS due to the immune dysfunction caused ...

www.ajpmfocus.org

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Reposted by Dr David Joffe MB BS(Hons), PhD, FRACP

Rosie de Kat 🌱🍉🍉 @rosiedekat.bsky.social · 8h

Dr Anthony Leonardi:

“All I have done is warn people and people find the warnings unpalatable. Not only that, people have given opinions on the trajectory of the virus and the immunology and have been blatantly wrong and are seeking a pound of flesh out of anger.”:

Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 8h

Agreed 🙏🏻🙏🏻

Fair to say that @fitterhappieraj.bsky.social was right about so very much!

thetyee.ca/Analysis/202...

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 8h

"Immunity Debt" is still rolled out with every Cövid wave.

Lazy Journalism and the opinions of those who repeat this mantra.

Pandemic 𓅃. Index @panaccindex.bsky.social · 8h

"Immunity debt" was a fraudulent PR campaign against NPIs, that the New York Times actively promoted.

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 8h

Yes... We have had this discussion.

Different pathogens with different pathways to end-organ injury.

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 8h

Agreed 🙏🏻🙏🏻

Fair to say that @fitterhappieraj.bsky.social was right about so very much!

thetyee.ca/Analysis/202...

4 25 59

Reposted by Dr David Joffe MB BS(Hons), PhD, FRACP

Eleanor Fielding @meownersclub.bsky.social · 13h

#ME #Disability #PEM #FanningTheFlames
@meassociation.org.uk
@longcovidsupport.bsky.social
#Justice4ME #Plan4ME
@ashleydaltonmp.bsky.social
@decodemestudy.bsky.social
@thelancet.com
@nhsengland.bsky.social
@georgemonbiot.bsky.social
@davidjoffe64.bsky.social
@drjoepajak.bsky.social

This is a cartoon pretending to be a shop coupon.

There is an image of a cat wearing glasses and reading books. Round the cat’s neck is a pendant with the words “Wise Cat”

The title says - “Do you suffer from outdated prejudices about #ME and #Long Covid?”

Wise Cat is saying “Stuff those prejudices down and see if you can squeeze a thought into the gap - here’s a link”.

The link is - https://meassociation.org.uk

Round the outside of the cartoon is a dotted line with scissors on it and the words ‘cut out and keep for those annoying relatives/friends/doctors’

The cartoon maker is #FanningTheFlames

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 1d

Diabetics and COVID.

Not great for your 🫀

www.frontiersin.org/journals/pha...

Frontiers | Diabetic cardiomyopathy and COVID-19: intersecting pathways and amplified cardiovascular risk

Diabetic cardiomyopathy (DCM) is a diabetes-induced heart condition characterized by ventricular dysfunction without other cardiac diseases. Chronic hypergly...

www.frontiersin.org

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 2d

More Bad JuJu for kids and Cøvid.

Cardiovascular health is something we should explore. Dyslipidaemia and endothelial injury aren't isolated to adults!

journals.lww.com/hhmi/fulltex...

journals.lww.com

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 3d

🧠 Daily Feed of Brain Damage 🧠

👇🏻👇🏻👇🏻

www.nature.com/articles/s44...

COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years - npj Dementia

npj Dementia - COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years

www.nature.com

1 34 86

Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 3d

Sorted

doi.org/10.1038/s414...

Paternal SARS-CoV-2 infection impacts sperm small noncoding RNAs and increases anxiety in offspring in a sex-dependent manner - Nature Communications

Whether paternal pre-conceptual SARS-CoV-2 infection impacts sperm RNA content, or effects offspring phenotypes, has not been previously investigated. Here authors report changes in sperm noncoding RNAs in SARS-CoV-2 infected sires and increased anxiety-like behaviors in offspring.

doi.org

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 3d

doi.org/10.1038/s414...

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 3d

🧠 Daily Feed of Brain Damage 🧠

Unborn Edition

nature.com/articles/s4146…

https://nature.com/articles/s4146…

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 3d

BULLSHIT ‼️🙏🏻

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 3d

Crap 🙏🏻

1

Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 4d

February 2020

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 4d

Influenza versus Cövid.

826 COVID vs 89 flu deaths, and within 90 days, 1,391 COVID vs 149 flu deaths, showing worse outcomes for COVID-19

Rough maths? About 10 times more fatal

journals.plos.org/plosmedicine...

Comparative risk of post-acute sequelae among adults following SARS-CoV-2 or influenza virus infection: A retrospective cohort study among United States adults

Author summary Why was this study done? It is known that people may suffer medical complications long after COVID-19, which are called post-acute sequelae (PAS). Similar sequelae are also known to h...

journals.plos.org

6 92 170

Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 4d

The cost of doing nothing☠️‼️

@binitakane.bsky.social 🙏🏻

jamanetwork.com/journals/jam...

Enduring Outcomes of COVID-19 Work Absences on the US Labor Market

This cohort study examines the extent to which COVID-19 continues to generate work absences and decrease labor force participation beyond the pandemic period in the US.

jamanetwork.com

3 42 110

Reposted by Dr David Joffe MB BS(Hons), PhD, FRACP

Eleanor Fielding @meownersclub.bsky.social · 4d

#ME #Disability #Psychiatry #Biopsychosocial
@meassociation.org.uk
@longcovidsupport.bsky.social
@thelancet.com
@nhsengland.bsky.social
@georgemonbiot.bsky.social
@profstevegriffin.bsky.social
@davidjoffe64.bsky.social
@drjoepajak.bsky.social

Title - This Week in Disbelief..

This is a cartoon in 3 vertical sections -

Section 1 title - "The Most Hated Doctor in Britain" has been appointed by a Labour government as vice-chair of an investigation into whether mental health problems and neurodivergence are being
OVERDIAGNOSED.

Section 2 title - Prof Simon Wessely, the careerist punitive psychiatrist whose views on #MEcfs have led to decades of underfunding, medical ignorance.
unnecessary disability and definitely preventable deaths. seems wedded to these powerful persecutory roles.

Section 3 title - How can we understand this commitment to coercion from a doctor?
Does he perhaps:
• Crave recognition from powerful groups?
• Struggle with unresolved trauma?
• Chase career and social gains?
• Lack self-awareness & empathy?
• Think the ends justify the means?

In the bottom right hand corner is wise Cat who’s saying “Or perhaps he's just a dick?!”

The cartoon maker is #FanningTheFlames

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 5d

A normal Lymphocyte differential is just numbers...

It tells you nothing about function‼️

www.frontiersin.org/journals/cel...

Frontiers | Persistent lymphocytopenia in convalescent patients with COVID-19: dysregulated B cell, CD4+ T cell, and treg compartments in 7–12% of moderate-severe cases

BackgroundLong COVID manifests with heterogeneous clinical outcomes, potentially linked to immune dysfunction. However, the recovery of immune-cell subsets d...

www.frontiersin.org

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Reposted by Dr David Joffe MB BS(Hons), PhD, FRACP

Eleanor Fielding @meownersclub.bsky.social · 5d

#ME #Disability #Psychiatry #Biopsychosocial
@meassociation.org.uk
@longcovidsupport.bsky.social
@thelancet.com
@nhsengland.bsky.social
@georgemonbiot.bsky.social
@profstevegriffin.bsky.social
@davidjoffe64.bsky.social
@drjoepajak.bsky.social

6 6

Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 6d

More Opthalmic complications of Cøvid. Vaccinations reduce the risk.

www.nature.com/articles/s41...

Ophthalmic complications associated with COVID-19: a large US national database analysis - Eye

Eye - Ophthalmic complications associated with COVID-19: a large US national database analysis

www.nature.com

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 6d

More Bad JuJu for the unborn 😔

www.nature.com/articles/s41...

SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability - Cell Death & Disease

Cell Death & Disease - SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability

www.nature.com

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 6d

That's a more complex question, Paul.

Myocarditis is common in MISC. The heart is rich in vessels. My assumption is it can happen acutely, or at an increased risk after the MISC has been treated. This hypothesis is based on the likely persistence of inflammation.

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 6d

MISC can occur with the first O et subsequent infections...

You don't get to choose

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Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 6d

www.mdpi.com/2077-0383/14...

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