Biplab Bose
biplabbose.bsky.social
Biplab Bose
@biplabbose.bsky.social
16 followers 74 following 35 posts
Biologist | Bookworm | Cycloholic | Birder | Trying to understand the design principles of Life using Mathematics and Physics | https://youtube.com/@sysbio https://fac.iitg.ac.in/biplabbose
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Julia keeps it rational.

1//3 + 1//6 == 1//2

Exact math. No floating-point drama.

#JuliaLang #lovingJulia #sillyposts
Statistical physics was built to understand gases.
Now we use it to understand flocks, tissues, and tumors. Same mathematics, new meanings—order out of interaction. Perhaps we should develop new thermodynamic variables beyond V, P, and T that are more suitable for living systems. #complexsystems
Between the animate and the inanimate lies a missing theory — not of matter, but of matter becoming intention. Or the concept of teleonomy is just another trap? Possibly! #complexity #physicsoflife
Physicists see the forest, mathematicians see the pattern, & biologists... name every tree, catalog leaf shapes, & write three papers on bark texture before asking why forests exist. Wish my friends from the Biology community would read and re-read the old classic: sciencedirect.com/science/arti...
Can a biologist fix a radio?—Or, what I learned while studying apoptosis
sciencedirect.com
If I want to teach undergraduate students about driven non-equilibrium systems, which two toy models should I choose? The mathematics must be intuitive, and the simulations must be easy. What do you suggest? #statmech #physics #complexsystem #systemsbiology
In #Julia, even the script evolves with time (without mutation) 😃

julia> @time sum(rand(10^7))
[0.086688 seconds, 57.81% gc time]

julia> @time sum(rand(10^7))
[0.026221 seconds, 29.82% gc time]
.
.
julia> @time sum(rand(10^7))
[0.017704 seconds, 2.34% gc time]

#Julialang #computing
Gradient systems give you landscapes. Non-gradient systems give you the weather. That's why cellular fate feels more like climate chaos than a downhill stroll on Waddington's landscape. #systemsbiology #dynamicalsystems #complexsystems
Reposted by Biplab Bose
How can we design complex computational systems using synthetic biology? Check our paper, where we use space as a computational element, dramatically reducing communication requirements while allowing modularity, reusability, scalability & minimal cell engineering.
journals.plos.org/ploscompbiol...
Embryonic development is robust but fluctuations and variations are inevitable. Nature smartly sells those variations as features not bug.
#systemsbiology #complexsystems
LLMs don’t live—yet they learn, adapt, and hallucinate. Strange! Is not it? Biologists need to rethink the key ideas of Life. #physicsoflife #mathbio #complexity #systemsbiology
Reposted by Biplab Bose
Data-driven modeling of complex biological systems

Thank you for joining us at today's NITMB Seminar with Cody FitzGerald, James S. McDonnell Foundation Postdoctoral Fellow at Northwestern University!

📽️ Watch the seminar recording - www.youtube.com/watch?v=B2Y9...
If you have to design a 40 hr UG course on Computational Biology, what topics will you include in the syllabus? As I see across institutes, this course is heavily biased to protein structure, molecular dynamics simulations and drug design. #compbio #qbio
f(x::Int, y::Int) = x + y
f(x::String, y::String) = x * y
# In Julia, even functions believe in pluralism.

#JuliaLang #FunInComputing #computingjokes #computing
Is it only me or for everyone- the feeds in the Bluesky Android app updates only when I use certain networks (ISPs) that too with lag.

#bluesky
#bsky
Switched to Julia 3 years ago. Still can’t uninstall MATLAB — held hostage by the interactive GUIs of dfield, pplane, and matcont.

#JuliaLang #computing #dynamicalsystems
Teaching Gillespie algorithm in the Systems Biology class and it reminds that Life is a process with long stretches of exponential calm punctuated by bursts of stochastic drama.

#stochastic
#random
#mathbio
#systemsbiology
#sysbio
Just updated my Vicsek model Julia code. Still amazes me how a bunch of clueless particles manage better collective behaviour than most meetings I've attended.

#SelfOrganization #ComplexSystems
#havefun
Missing an Easter-egg function in Julia? Try my WhyJulia. Every time you call why(), it prints a random witty statement — sometimes profound, often nonsensical, but always entertaining.

github.com/biplabbose/W...

#JuliaLang #JuliaLanguage
#JustKidding #fun
#computing
Some people have midlife crises. Dynamical systems have pitchfork bifurcations.

#justkidding #dynamicalsystems #mathbio
cat = rand(Bool)
println(cat ? "😺 Alive!" : "💀 Dead!")

Even Schrödinger’s cat deserves Julia.
#JuliaLang #codingbasics
If a phenomenon is mathematically possible, then we may observe it in reality, but a mathematically impossible one can never be real.

#math #mathmodel #mathbio
We study living matter because dead matter got boring after Newton.

#physicsoflivingmatter
#systemsbiology
#complexsystems
#physicsoflife
I left wet-lab experiments 'cause those are damn slow! Equations are better; they evolve faster than organisms. 🙂#mathbio #systemsbiology #sysbio #qbio #computaionalbiology