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Alexis Rohou @alexisrohou.bsky.social · 4h

Trigger warning.

Richard Sever @richardsever.bsky.social · 17h

Just printing out a paper to read. So glad the figures are at the end so I can look at them alongside whatever bit of the text I want to, rather than in-line making me have to flip back to the first in-text callout 😜 @pracheeac.bsky.social

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Alexis Rohou @alexisrohou.bsky.social · 14h

@sjorsscheres.bsky.social recently gave a seminar where, in a slightly different context, he spoke of spaghetti for completely disordered part of a sequence, but “al dente” for a part of the sequence which solution NMR suggested was elongated, not quite random. Loved that.

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Alexis Rohou @alexisrohou.bsky.social · 2d

The PDB and EMDB do not have nor claim to have nor want to have the authority to decide whether a particular entry should be accepted or published. They see their role as providing information and advice to depositors and reviewers.

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James Fallows @jfallows.bsky.social · 3d

Re-upping:

Excellent assessment of John "Roger Taney" Roberts.

In @harvardmagazine.bsky.social , by Lincoln Caplan.

As careful, legally informed, judicious-minded writer as you're going to find. With an unsparing judgment.

www.harvardmagazine.com/legal/suprem...

What Trump Means for John Roberts's Legacy | Harvard Magazine

Executive power is on the docket at the Supreme Court.

www.harvardmagazine.com

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Alexis Rohou @alexisrohou.bsky.social · 3d

Got it. Thanks for taking the time to spell it out.

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Alexis Rohou @alexisrohou.bsky.social · 3d

… manichean, and less interesting than the article I linked, which emphasizes much more the role of government and the conditions under which it can be effective (for spells of history) and covers many more aspects of public life and governance than “just” tech. Still I’ll add that book to my list.

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Alexis Rohou @alexisrohou.bsky.social · 3d

Thanks, I’ll take a look but at first glance the book summary, it’s online reviews and the highlight from that video (the bit they edited for the first few seconds and the dramatic title) make his arguments seem much more narrow (purely about tech and about recent years),…

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Alexis Rohou @alexisrohou.bsky.social · 3d

An insightful read. I hadn’t appreciated the links between feudalism and privatization. The author’s evocation of how future historians may look back on our era in that respect felt important, and a fruitful way to think, to me. I’m hopeful the pendulum will swing back towards effective government.

Feudalism Is Our Future

What the next Dark Ages could look like

www.theatlantic.com

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Alejandro Llorente, Ph.D. @llorentealejandro.bsky.social · 6d

1/9 🚀 Big news! As a result of 5 years of my PhD, building on a 30-year dream of my PI Dr. Nancy Carrasco, we think we've found a new way to treat cancer! We’ve released our preprint & I'm so excited to share this story! 🧵
www.biorxiv.org/content/10.1...
#Science #proteinengineering #proteindesing

Engineering substrate selectivity in the human sodium/iodide symporter (NIS)

Iodide (I-) uptake mediated by the Na+/I- symporter (NIS) is the first step in the biosynthesis of the thyroid hormones, of which I- is an essential constituent. NIS couples the inward transport of I-...

www.biorxiv.org

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Alexis Rohou @alexisrohou.bsky.social · 6d

Congratulations!!

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Oded Rechavi @odedrechavi.bsky.social · 7d

Fwd: Fwd: “I hope this email finds you well”

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Michael Gilman @gilman.bsky.social · 8d

Love this story about one of today's Nobel winners, Mary Brunkow.

(She and colleague Fred Ramsdell, working at Celltech (RIP), uncovered the role of Foxp3 in the development of Tregs.)

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Science Magazine @science.org · 8d

This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi

Medicine Nobel goes to three researchers who identified immune system’s security guards

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease

scim.ag

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Aman Husbands @husbandslab.bsky.social · 11d

RIP to the legend

Ma$on @masonfromtwitter.bsky.social · 11d

It's pronounced "bouquet"

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Alexis Rohou @alexisrohou.bsky.social · 14d

I hadn't realized Robert Oppenheimer was a francophone. A few pearls in there. Last question: "Einstein is often quoted as saying if he had to do it all over again he'd be a plumber... what about you?" Oppenheimer: "I am very glad that the human condition means one never has to answer this question"

1958 : Entretien avec Oppenheimer, le père de la bombe atomique | Archive INA

YouTube video by INA Histoire

www.youtube.com

Alexis Rohou @alexisrohou.bsky.social · 16d

The end of an era. An outstanding body of broadcasting work.

Melvyn Bragg steps down from BBC Radio 4's In Our Time after 26 years

The veteran presenter has hosted more than 1,000 epsiodes of the programme over the past 26 years.

www.bbc.com

Alexis Rohou @alexisrohou.bsky.social · 20d

Wow. This seems excellent. I assume it will force some journals to change policies regarding embargoes (revised preprint must be published after peer review but before publication).

Richard Sever @richardsever.bsky.social · 20d

HHMI adopts Plan U journals.plos.org/plosbiology/...

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Rebecca R Helm @rebeccarhelm.bsky.social · 20d

I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA

10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)

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Alexis Rohou @alexisrohou.bsky.social · 20d

Would someone care to write a summary thread for the lazy among us?

Alexis Rohou @alexisrohou.bsky.social · 21d

What?!? I’m sorry that’s happening to you two. Grrrrrrrr.

Alexis Rohou @alexisrohou.bsky.social · 24d

www.uscis.gov/sites/defaul...

Actually will only affect new H1B petitions.

www.uscis.gov

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Alexis Rohou @alexisrohou.bsky.social · 25d

Not sure. Below is a useful account to follow on immigration matters. bsky.app/profile/reic...

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Old White Nepo Hat @kenwhite.bsky.social · 26d

Can Jimmy Kimmel sue Brendan Carr, or other federal actors, for violating his First Amendment rights by coercing ABC to suspend his show, and maybe eventually to fire him?

To teal deer it, yes, but without an effective remedy.

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Alister Burt @alisterburt.bsky.social · 27d

@grigoriefflab.bsky.social continues to push limits 👀

bioRxivpreprint @biorxivpreprint.bsky.social · 28d

Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching https://www.biorxiv.org/content/10.1101/2025.09.11.675606v1

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Joe Stieb @joestieb.bsky.social · Sep 13

The right sets the terms of our political discourse in so many ways, one of which is the idea that there isn't enough "debate" and "free speech" on campus.

We need to push back on this. The truth is (speaking for myself as a history prof), I don't really emphasize debate much in my classes/

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