Scholar
LightNews

Stefan Schandelmaier

Videos
H-index: 33
Mathematics 33%
Economics 25%
more

Reposted by Stefan Schandelmaier, David Tovey

richardhooper.bsky.social
J Clin EPi @jclinepi.bsky.social has a unique focus on meta-research. I've co-led a November editorial reflecting on the variety its content, and how an even richer balance might be achieved. Methodologists assemble! www.jclinepi.com/article/S089... @davidit.bsky.social @andreatricco.bsky.social
What advice can we offer to authors? Reflections from the statisticians’ bench
What are the statistical issues on which the Journal of Clinical Epidemiology editorial team should be offering advice to authors? Lists of statistical bugbears and elephant traps in health research r...
www.jclinepi.com
1 13 27

Reposted by Stefan Schandelmaier

clinepi-basel.bsky.social
With over 96% of global trial data on this topic included, this #IPDMA, published in @lancetrespirmed.bsky.social and initiated by #EU-RESPONSE, provides the most comprehensive analysis for JAK inhibitors for adults hospitalized due to #COVID19.

Full article: www.thelancet.com/journals/lan...
Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials
This IPDMA of RCTs in adults admitted to hospital due to COVID-19 found that JAK inhibitors reduced mortality across all levels of respiratory support, independent of dexamethasone or tocilizumab, and...
www.thelancet.com
1 4 4

by Stefan Schandelmaier

sschandelmaier.bsky.social
Finally!
www.bbc.com/news/article...
AfD classified as extreme-right by German intelligence
The AfD came second in February elections and has a record number of seats in the new parliament.
www.bbc.com

by Stefan Schandelmaier

sschandelmaier.bsky.social
I’m thrilled that leading research groups now recommend our #ICEMANtool to evaluate possible subgroup effects:
#Cochrane in their handbook Chapter 10.6
#GRADE in their guidance No. 36
Germany's #IQWIG in their general methods
www.iceman.help
www.cmaj.ca/content/192/...
ICEMAN
Welcome to the web pages for ICEMAN! ICEMAN is an instrument to help researchers identify credible effect modification (also called subgroup effect, statistical interaction, moderation, or heterogenei...
www.iceman.help
3

Reposted by Stefan Schandelmaier, Anne van Aaken, Marina Dossena

chriso-wiki.bsky.social
Ian Fleming's original James Bond novels haven't aged well. For example, Moonraker - published almost exactly 70 years ago in April 1955 - features a villain who's a super-rich industrialist and rocket-maker seeking to cause chaos because he's a secret Nazi. Such a silly idea!
a man with a beard is sitting in a room with a harp in the background
ALT: a man with a beard is sitting in a room with a harp in the background
media.tenor.com
92 2.8K 6.9K

Reposted by Stefan Schandelmaier

nisreenalwan.bsky.social
Hi @bmj.com
Can you add a Bluesky share button instead of the X button you have please?
1 29 150

Reposted by Stefan Schandelmaier, Scott F. Kiesling, Helen Schwenken , and 2 more

marc-fischer.bsky.social
Time to evict AirBnB from your life, if you have't already.
Airbnb’s co-founder is joining Elon Musk’s DOGE
Gebbia, a close friend of Musk, has praised DOGE’s work and defended it against criticisms on social media
www.independent.co.uk
200 2.6K 4.6K

by Thomas Agoritsas — Reposted by Stefan Schandelmaier

thomasagoritsas.bsky.social
Have you checked our risk-stratified #RapidRecs on #PCSK9 inhibitors and #ezetimibe for the reduction of cardiovascular events ?
@magicevidence.bsky.social @bmj.com
-->https://www.bmj.com/content/377/bmj-2021-069066
3 2

Reposted by Stefan Schandelmaier

adamjkucharski.bsky.social
The risks of backing scattered islands of sensible points in a sea of nonsense: kucharski.substack.com/p/islands-of...
11 32

by Stefan Schandelmaier

sschandelmaier.bsky.social
www.thelancet.com/journals/lan...
Health in the age of disinformation
Health misinformation (false or misleading data shared unintentionally) and disinformation (deliberately deceptive information) are not new, but the COVID-19 pandemic marked a turning point. The sense...
www.thelancet.com
2

by Stefan Schandelmaier

sschandelmaier.bsky.social
So true!
gvleioras.bsky.social
Georgios Vleioras @gvleioras.bsky.social · Jan 11
I just saw this elsewhere and it made me think of our discussion here:
1

Reposted by Stefan Schandelmaier

gvleioras.bsky.social
I just saw this elsewhere and it made me think of our discussion here:
8 23

by Stefan Schandelmaier

sschandelmaier.bsky.social
A better statistic might be the prediction interval but in my view the community needs to develop more experience with it before we can use it to confidentially judge relevance of heterogeneity (if ever). And unfortunately it does not work very well in a meta-analysis with only a few studies

by Stefan Schandelmaier

sschandelmaier.bsky.social
True. But what else can we do? A paper in the new Core GRADE series (currently under revision in the BMJ) offers a practical solution based on visual inspection of both overlap of confidence intervals (similar to I2) but also where point estimates lie in relation to a relevance threshold.
1

Reposted by Stefan Schandelmaier

peterrowlett.net
Happy New Year! I wrote a list of numerical coincidences involving 2025, see if you spot something fun!

#MathsSky #MathSky #MathsToday #MathChat
Numerical coincidences for 2025
There seem to be a lot of numerical coincidences bouncing around concerning the new year 2025. For example, it’s a square number: \( 2025 = 45^2 \). The last square year was \(44^2 = 1936\), …
aperiodical.com
16 36 100

by Stefan Schandelmaier

sschandelmaier.bsky.social
www.ted.com/talks/jimmy_...
Why I believe the mistreatment of women is the number one human rights abuse
With his signature resolve, former US President Jimmy Carter dives into three unexpected reasons why the mistreatment of women and girls continues in so many manifestations in so many parts of the wor...
www.ted.com
2 3

Reposted by Stefan Schandelmaier

hildabast.bsky.social
Ever wonder about the basis for fear-mongering & conspiracy theories about mRNA vax? Wish you had a place to go when someone cites "proof"?

I've got you covered! In my latest @plos.org I buckle up for the waves of anti-vax muck likely to come in 2025. 1/2

absolutelymaybe.plos.org/2024/12/28/g...
Getting Ready for More mRNA Vaccine Fear-Mongering: A Compendium - Absolutely Maybe
Recently, I wrote about a depressingly successful campaign against the introduction of a next generation Covid vaccine in Japan. It is a…
absolutelymaybe.plos.org
15 77 170

Reposted by Stefan Schandelmaier

georgetakei.bsky.social
Vaccines stopped polio.
The image is a graph titled "Reported paralytic polio cases and deaths, United States, 1910 to 2019," from Our World in Data. It shows the annual number of polio cases (in red) and deaths (in green). A sharp decline in both cases and deaths occurs after the introduction of the polio vaccine in 1957, which is marked with an arrow labeled "Vaccine introduced in 1957." The graph illustrates the dramatic impact of vaccination on reducing polio cases and fatalities over time.
97 770 3.6K

Reposted by Stefan Schandelmaier

schwenkej.bsky.social
1/ Excited to share thoughts on two excellent blog posts about clinical trials! First up: "The Case for Clinical Trial Abundance" by @ruxandrabio.bsky.social and Willy Chertman . They argue we need more clinical trials & that bureaucracy hampers faster progress. A sentiment I fully share!
The case for clinical trial abundance
A supply-side reform agenda for one of our most urgent problems
www.slowboring.com
1 1 7

by Stefan Schandelmaier

sschandelmaier.bsky.social
Methods guidance is evolving. Here the authors chose to provide explicit recommendations both in favor but also agains certain methods. I think that that’s the way forward!
vickersbiostats.bsky.social
Andrew Vickers @vickersbiostats.bsky.social · Dec 16
Very nice summary recommendations on how to evaluate a prediction model from a group of top researchers in the field.
1

by Stefan Schandelmaier

sschandelmaier.bsky.social
Great! Will include it in @lightsdatabase.bsky.social
1

Reposted by Stefan Schandelmaier

vickersbiostats.bsky.social
Very nice summary recommendations on how to evaluate a prediction model from a group of top researchers in the field.
2 8 36

Reposted by Stefan Schandelmaier

miguelhernan.org
Does #randomization ensures balance of risk factors between groups? Consider this:

In Denmark 860 individuals were randomly allocated to either intervention or control. Individuals were unaware of their allocation. No intervention took place. Mortality was higher in the intervention group (p=0.003)
7 47 130

Reposted by Stefan Schandelmaier

hakwan.bsky.social
www.theguardian.com/technology/2...

hats off to @deevybee.bsky.social . my highest respect.
Oxford scientist resigns from Royal Society over Elon Musk’s continuing fellowship
Prof Dorothy Bishop said fellowship was ‘a contradiction of all the values’ of UK’s national academy of sciences
www.theguardian.com
1 8 67

Reposted by Stefan Schandelmaier, Kevin McManus

rorinstitute.bsky.social
Launching this week, MetaROR will be a free, open platform where anyone working with metaresearch can share their work and receive transparent, open peer reviews.

Join us at one of our launch events to find out more: researchonresearch.org/metaror-laun...
10 17

Reposted by Stefan Schandelmaier

hpspodcast.bsky.social
"We need to get [scientists] to realise that history and philosophy of science has much to contribute to science itself"

A highly quotable episode with Editor-in-Chief of Science @holdenthorp.bsky.social

Out on @hpspodcast.bsky.social now!

#hps #philsci #histsci #sts🧪
S4 Ep 9 - Holden Thorp on 'Teach History and Philosophy of Science' - The HPS Podcast - Conversations from History, Philosophy and Social Studies of Science
“This is Holden Thorp. I'm the Editor in Chief of Science and thanks to Sam and Carmelina for all they're doing to get the word out about the history and philosophy of science”Today's guest is Holden ...
thehpspodcast.buzzsprout.com
11 33 120

Reposted by Stefan Schandelmaier

guardian-world-rss.bsky.social
Quincy Jones, producer and entertainment powerhouse, dies aged 91
Quincy Jones, producer and entertainment powerhouse, dies aged 91
Widely and wildly talented musician and industry mogul worked with Michael Jackson, Frank Sinatra, Will Smith and others
www.theguardian.com
2 32 57

by Stefan Schandelmaier

sschandelmaier.bsky.social
Hi qualitative researchers!

For my teaching, I was searching for something like PICO for qualitative. I found SPIDER and like it! pubmed.ncbi.nlm.nih.gov/22829486/

Is anybody aware of any other scheme for systematic question / problem / objective formulation in a qualitative study?

Reposted by Stefan Schandelmaier

statsepi.bsky.social
For patient-focused research, there are very few useful research aims, and none of them are "identifying risk factors.”

Seriously! 😜

(ICYMI)

statsepi.substack.com/p/sorry-what...
Sorry, what was the question again?
And again. And again. And again...
statsepi.substack.com
2 7 19

by Stefan Schandelmaier

sschandelmaier.bsky.social
Did you just present new #TrialsMethodology guidance at #ICTMC2024? Have a look at our new database and check whether it is already in it. If not, send it along!
lights.science
Homepage - LIGHTS
The Library of Guidance for Health Scientists. A living database for methods guidance.
lights.science
1 3

References

Fields & subjects

Updated 1m