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Matthew I. Gibson

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Reposted by Matthew I. Gibson

sciencex.bsky.social
A new cryopreservation method using polyampholytes, DMSO, and trehalose significantly reduces thaw time for red blood cells, supporting faster emergency transfusions and improved blood storage. doi.org/g92knc
Blood on demand: New freezing method slashes thaw time for emergency blood transfusions
A transformative new method for freezing human red blood cells has been developed by researchers from the Universities of Manchester and Leeds.
medicalxpress.com
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by Matthew I. Gibson

labgibson.bsky.social
and press release here.
www.manchester.ac.uk/about/news/s...
Scientists develop groundbreaking ‘blood on demand’ technology to revolutionise emergency transfusions
Rapid washout: Cocktail-treated RBCs can be washed and prepared for transfusion in just 25 minutes – compared to over 75 minutes for glycerol.Higher recovery rates: The new method results in an averag...
www.manchester.ac.uk
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by Matthew I. Gibson

labgibson.bsky.social
Our work showing how our macromolecular cryoprotectants unlock "blood on demand' is now published! @uommib.bsky.social From the freezer to fully washed in just 25 minutes, compared to 75 mins using glycerol. Partnership with Tom Whale, Fraser Macrae and more.
www.sciencedirect.com/science/arti....
Towards blood on demand: Rapid post-thaw isolation of red blood cells from multicomponent cryoprotectants
Severe blood loss due to trauma, anaemia, or chemotherapy necessitates immediate red blood cell (RBC) transfusions. The short shelf-life of RBCs at 4 …
www.sciencedirect.com
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Reposted by Matthew I. Gibson

manchester.ac.uk
ANNOUNCED: The University of Manchester and Bupa have launched an innovative new collaboration to drastically reduce the healthcare sector’s environmental impact on our planet 🌍

www.manchester.ac.uk/about/news/u...
University of Manchester and Bupa combine to affect change on environmental impact of healthcare sector
The University of Manchester and Bupa have announced an innovative new collaboration to develop new methods and strategies to drastically reduce the healthcare sector’s environmental impact upon our p...
www.manchester.ac.uk
3 7

by Michael Veale — Reposted by Matthew I. Gibson, Elizabeth Stokoe, Du Plessis , and 9 more

michae.lv
Self-inflicted embarrassment for the University of Warwick — first it rebrands hyper-generically, then someone totally unhinged decides the *front page of the uni website* should say ‘Learn more about our Brand’.
Front page of Warwick.ac.uk
78 100 520

by Matthew I. Gibson

Reposted by Matthew I. Gibson

Reposted by Matthew I. Gibson

Reposted by Matthew I. Gibson

by Matthew I. Gibson

labgibson.bsky.social
Was a fun meeting and nice to catch up with so many colleagues and collaborators.
2

Reposted by Matthew I. Gibson

by Matthew I. Gibson

labgibson.bsky.social
Our latest work is out. Glyconanoparticles with complex branched glycans to interrogate influenza binding, with no labels in a microplate. Nice academic/industry collaboration @uommib.bsky.social with Iceni and AZ, and Rob Field. onlinelibrary.wiley.com/doi/10.1002/...
Label‐Free and Microplate‐Based Dissection of Glycan‐Virus Interactions Using Polymer‐Tethered Glyconanoparticles
This work demonstrates the use of polymer-tethered glycosylated gold nanoparticles for the label-free evaluation of influenza virus binding in a simple microplate. Sialylated linear and branched glyc...
onlinelibrary.wiley.com
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by Matthew I. Gibson

labgibson.bsky.social
Our team's dedicated microscopy platform for (live) cell imaging is set up @uommib.bsky.social : spinning disk confocal + high-content microscopes, + flow cytometer. This will accelerate our biomaterials discovery for cryo/glyco sciences. Credit to @akalabyabissoyi.bsky.social for hard work!
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by Matthew I. Gibson

labgibson.bsky.social
Today I’ll be visiting my Alma Mater, Durham Chemistry, as part of my Corday-Morgan lecture series. I’ll present our latest advances in (macro)molecules for cryobiology.
2

by Matthew I. Gibson

labgibson.bsky.social
Registration is now open for the Annual MacroGroupUK Symposia and Medal Award Lectures, hosted @uommib.bsky.social 8/9th September. Fabulous line up of speakers. Thanks to sponsors, we have poster prizes and low registration including all refreshments .
www.eventbrite.co.uk/e/2025-macro...
2025 MacroGroup Annual Symposia and Medal Lectures
Get ready for two jam-packed days of talks, discussions, and prestigious medal lectures at the 2025 MacroGroup Annual Symposia!
www.eventbrite.co.uk
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Reposted by Matthew I. Gibson

Reposted by Matthew I. Gibson

by Matthew I. Gibson

labgibson.bsky.social
This will let us explore the benefits of PVAylation, which is not only ice-binding, water soluble, low toxicity, but is also degradable in the environment

by Matthew I. Gibson

labgibson.bsky.social
This has been a challenge for us, due to lability of the RAFT end-group after deprotection giving us low conversion. Using a photo-reduction, we can cap the reactive end group and install bio-conjugation functionality at the other end.
1

by Matthew I. Gibson

labgibson.bsky.social
Our latest from Doug is out @chemicalscience.rsc.org @uommib.bsky.social . We introduce #PVAylation: site specific bioconjugation of PVA to proteins, bringing unique ice-binding capability as well as other benefits of polymer-conjugation. pubs.rsc.org/en/content/a...
PVAylation: precision end-functionalized poly(vinyl alcohol) for site-selective bioconjugation
The (bio)conjugation of polymers onto proteins enhances their pharmacokinetics and stability, most commonly using PEG (polyethylene glycol), but there is a need for alternatives. Poly(vinyl alcohol), ...
pubs.rsc.org
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Reposted by Matthew I. Gibson

by Matthew I. Gibson

Reposted by Matthew I. Gibson, Michael S. Rosenberg, Mark E. Schaffer , and 3 more

oregonthedm.bsky.social
Biggest commitment to a 3 second joke I've ever seen
880 28K 89K

Reposted by Matthew I. Gibson

Reposted by Matthew I. Gibson

by Matthew I. Gibson

labgibson.bsky.social
We have 3 talks #ACSSpring2025 from the team. Glycodiagnostics, covalent glycocalyx-targeting gene delivery and new poly(oxazoline) materials.
1

by Matthew I. Gibson

Reposted by Matthew I. Gibson

by Matthew I. Gibson

labgibson.bsky.social
We have another #postdoc vacancy @uommib.bsky.social . Join us to explore new applications of glycan-nanodiagnostics, with our partners Iceni Glycoscience and Field Lab. #glycotime We have world-class facilities in great environment. Pls RT.
www.jobs.manchester.ac.uk/Job/JobDetai...
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by Matthew I. Gibson

References

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