#microsky #phagesky
A DNA-mimicking protein antagonises #phage SPbeta’s repressor and connects SOS response to the control of lysis-lysogeny
www.biorxiv.org/content/10.1...
A DNA-mimicking protein antagonises #phage SPbeta’s repressor and connects SOS response to the control of lysis-lysogeny
www.biorxiv.org/content/10.1...
An unprecedented DNA recognition–mimicry switch governs induction in arbitrium phages
Temperate phages integrate multiple information sources to regulate lysis-lysogeny transitions. SPBeta-like phages use arbitrium signalling and DNA damage to control repressor activity during lytic in...
www.biorxiv.org
December 3, 2025 at 8:27 PM
#microsky #phagesky
A DNA-mimicking protein antagonises #phage SPbeta’s repressor and connects SOS response to the control of lysis-lysogeny
www.biorxiv.org/content/10.1...
A DNA-mimicking protein antagonises #phage SPbeta’s repressor and connects SOS response to the control of lysis-lysogeny
www.biorxiv.org/content/10.1...
Excited to share our latest work with @albertomarina.bsky.social and @avigdoreldar.bsky.social labs, where we decipher the mechanism by which SPβ-like phages sense the SOS response to control the lysis–lysogeny switch. www.biorxiv.org/content/10.1...
An unprecedented DNA recognition–mimicry switch governs induction in arbitrium phages
Temperate phages integrate multiple information sources to regulate lysis-lysogeny transitions. SPBeta-like phages use arbitrium signalling and DNA damage to control repressor activity during lytic in...
www.biorxiv.org
December 2, 2025 at 9:31 AM
Excited to share our latest work with @albertomarina.bsky.social and @avigdoreldar.bsky.social labs, where we decipher the mechanism by which SPβ-like phages sense the SOS response to control the lysis–lysogeny switch. www.biorxiv.org/content/10.1...
I will be defending on Dec 8th at 1pm Eastern Time! I will be sharing both published and new work. If filamentous phages, Pseudomonas aeruginosa, evolution, and active lysogeny sound cool:
It is hybrid, and the zoom link info can be found on the webpage. 🔗
calendar.pitt.edu/event/filame...
It is hybrid, and the zoom link info can be found on the webpage. 🔗
calendar.pitt.edu/event/filame...
Filamentous Prophage as Drivers of Rapid Bacterial and Phage Evolution
calendar.pitt.edu
November 4, 2025 at 2:54 PM
I will be defending on Dec 8th at 1pm Eastern Time! I will be sharing both published and new work. If filamentous phages, Pseudomonas aeruginosa, evolution, and active lysogeny sound cool:
It is hybrid, and the zoom link info can be found on the webpage. 🔗
calendar.pitt.edu/event/filame...
It is hybrid, and the zoom link info can be found on the webpage. 🔗
calendar.pitt.edu/event/filame...
Our latest work reveals that arbitrium phages cross-communicate across species! These tiny viruses “listen” to signals from others, coordinating lysis-lysogeny decisions across species.
Original idea from @albertomarina.bsky.social and, as usual, he was right.
www.biorxiv.org/content/10.1...
Original idea from @albertomarina.bsky.social and, as usual, he was right.
www.biorxiv.org/content/10.1...
Phages communicate across species to shape microbial ecosystems
Arbitrium is a communication system that helps bacteriophages decide between lysis and lysogeny via secreted peptides. In arbitrium, the AimP peptide binds its cognate AimR receptor to repress aimX ex...
www.biorxiv.org
October 14, 2025 at 1:36 PM
Our latest work reveals that arbitrium phages cross-communicate across species! These tiny viruses “listen” to signals from others, coordinating lysis-lysogeny decisions across species.
Original idea from @albertomarina.bsky.social and, as usual, he was right.
www.biorxiv.org/content/10.1...
Original idea from @albertomarina.bsky.social and, as usual, he was right.
www.biorxiv.org/content/10.1...
Julia Pollack, In Fragments No Longer, 2023 #sciart
Digital print depicting Lysogeny broth (LB) plates that hold the personal microbes of Pollack and Claudia Lutz.
Digital print depicting Lysogeny broth (LB) plates that hold the personal microbes of Pollack and Claudia Lutz.
October 14, 2025 at 1:27 PM
Julia Pollack, In Fragments No Longer, 2023 #sciart
Digital print depicting Lysogeny broth (LB) plates that hold the personal microbes of Pollack and Claudia Lutz.
Digital print depicting Lysogeny broth (LB) plates that hold the personal microbes of Pollack and Claudia Lutz.
Good morning Phage [Ph]ans! I'm so stoked to share my first preprint with the @jrpenades.bsky.social lab! We show that phages can use the arbitrium system to crosstalk and regulate lysis-lysogeny, which has huge implications in how phages shape microbial communities!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Phages communicate across species to shape microbial ecosystems
Arbitrium is a communication system that helps bacteriophages decide between lysis and lysogeny via secreted peptides. In arbitrium, the AimP peptide binds its cognate AimR receptor to repress aimX ex...
www.biorxiv.org
October 14, 2025 at 11:59 AM
Good morning Phage [Ph]ans! I'm so stoked to share my first preprint with the @jrpenades.bsky.social lab! We show that phages can use the arbitrium system to crosstalk and regulate lysis-lysogeny, which has huge implications in how phages shape microbial communities!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
They isolated the MulchMansion-MulchRoom system, relatives of the MindFlayer-MiniFlayer system. Their satellite (MulchRoom) is temperate, as you would expect from a satellite (it should be able to lay dormant until the helper enters the host). Instead, MiniFlayer lacks the lysogeny module. [4/n]
November 12, 2023 at 4:57 AM
They isolated the MulchMansion-MulchRoom system, relatives of the MindFlayer-MiniFlayer system. Their satellite (MulchRoom) is temperate, as you would expect from a satellite (it should be able to lay dormant until the helper enters the host). Instead, MiniFlayer lacks the lysogeny module. [4/n]
Hard to consider classical pseudo-lysogeny, since bacteria were grown to be sequenced and purely non-replicative phages should have been washed out. And they do not seem to be phage-plasmids. This work suggests virulent phages may persist for some time in small clonal non-structured populations.
January 3, 2025 at 9:56 AM
Hard to consider classical pseudo-lysogeny, since bacteria were grown to be sequenced and purely non-replicative phages should have been washed out. And they do not seem to be phage-plasmids. This work suggests virulent phages may persist for some time in small clonal non-structured populations.
2/ Lwoff's discovery built on his work in the early 1950s to understand lysogeny. This is when some genes of some viruses, bacteriophages (phage), get incorporated into the genetic material of a bacteria but remain latent until the formation of a new phage triggered by a particular event.
May 8, 2025 at 11:01 AM
2/ Lwoff's discovery built on his work in the early 1950s to understand lysogeny. This is when some genes of some viruses, bacteriophages (phage), get incorporated into the genetic material of a bacteria but remain latent until the formation of a new phage triggered by a particular event.
An Eco-evolutionary Model on Surviving Lysogeny Through Grounding and Accumulation of Prophages rd.springer.com/article/10.1... #jcampubs
An Eco-evolutionary Model on Surviving Lysogeny Through Grounding and Accumulation of Prophages - Mi...
Temperate phages integrate into the bacterial genomes propagating along with the bacterial genomes. Multiple phage elements, representing diverse prophages, are present in most bacterial genomes. The ...
rd.springer.com
October 16, 2023 at 12:58 PM
An Eco-evolutionary Model on Surviving Lysogeny Through Grounding and Accumulation of Prophages rd.springer.com/article/10.1... #jcampubs
Lysogeny destabilizes computationally simulated microbiomes https://www.biorxiv.org/content/10.1101/2023.10.23.563560v1
Lysogeny destabilizes computationally simulated microbiomes https://www.biorxiv.org/content/10.1101/2023.10.23.563560v1
Background: The Anna Karenina Principle predicts that stability in host-associated microbiomes corre
www.biorxiv.org
October 25, 2023 at 3:31 AM
Lysogeny destabilizes computationally simulated microbiomes https://www.biorxiv.org/content/10.1101/2023.10.23.563560v1
Arbitrium phages can manipulate each other's lysis - lysogeny decisions https://www.biorxiv.org/content/10.1101/2025.10.13.681967v1
October 14, 2025 at 5:32 PM
Arbitrium phages can manipulate each other's lysis - lysogeny decisions https://www.biorxiv.org/content/10.1101/2025.10.13.681967v1
👉 Katharina Kohm receives the PhD award of the
@vaam-microbes.bsky.social at the annual congress in Bochum! Congratulations! 🥂🌹
She identified the key components involved in controlling lysis-lysogeny decisions of the Bacillus subtilis phage SPbeta.
@unihohenheim.bsky.social #subtiwiki
@vaam-microbes.bsky.social at the annual congress in Bochum! Congratulations! 🥂🌹
She identified the key components involved in controlling lysis-lysogeny decisions of the Bacillus subtilis phage SPbeta.
@unihohenheim.bsky.social #subtiwiki
March 26, 2025 at 10:13 AM
👉 Katharina Kohm receives the PhD award of the
@vaam-microbes.bsky.social at the annual congress in Bochum! Congratulations! 🥂🌹
She identified the key components involved in controlling lysis-lysogeny decisions of the Bacillus subtilis phage SPbeta.
@unihohenheim.bsky.social #subtiwiki
@vaam-microbes.bsky.social at the annual congress in Bochum! Congratulations! 🥂🌹
She identified the key components involved in controlling lysis-lysogeny decisions of the Bacillus subtilis phage SPbeta.
@unihohenheim.bsky.social #subtiwiki
Haha I read your message and then immediately bumped into my colleague Heather Allison (temperate phage expert)... She says she has seen everything — expressed by their own promoters during lysogeny, modulated by genomic location (controlled by host), and expressed during lytic phase.
November 3, 2023 at 9:32 AM
Haha I read your message and then immediately bumped into my colleague Heather Allison (temperate phage expert)... She says she has seen everything — expressed by their own promoters during lysogeny, modulated by genomic location (controlled by host), and expressed during lytic phase.
My auto-correct corrected misogyny into lysogeny
April 6, 2025 at 7:56 PM
My auto-correct corrected misogyny into lysogeny
What are the benefits of lysogeny for host & phage? When did lysogeny evolve, & how does it underpin divresity of disease caused by Strep? Love how @MarthaClokie’s talk feels like a nature documentary! #microbio18
April 10, 2018 at 11:05 AM
What are the benefits of lysogeny for host & phage? When did lysogeny evolve, & how does it underpin divresity of disease caused by Strep? Love how @MarthaClokie’s talk feels like a nature documentary! #microbio18
What was cut? The parts that seemed too difficult or unresolved, including
Cell modulation, including lysis, lysogeny, and virocells
The basis for and methods to measure viral diversity
Viral dynamics in explicit spatial contexts
& of course
Models of viruses, microbes & macro-organisms.
Cell modulation, including lysis, lysogeny, and virocells
The basis for and methods to measure viral diversity
Viral dynamics in explicit spatial contexts
& of course
Models of viruses, microbes & macro-organisms.
October 16, 2025 at 8:50 PM
What was cut? The parts that seemed too difficult or unresolved, including
Cell modulation, including lysis, lysogeny, and virocells
The basis for and methods to measure viral diversity
Viral dynamics in explicit spatial contexts
& of course
Models of viruses, microbes & macro-organisms.
Cell modulation, including lysis, lysogeny, and virocells
The basis for and methods to measure viral diversity
Viral dynamics in explicit spatial contexts
& of course
Models of viruses, microbes & macro-organisms.
Can it be this is the only Rizosphere #Virus talk in the conference?!
"Rhizosphere-triggered viral #lysogeny mediates microbial
metabolic reprogramming to enhance #arsenic oxidation
» Ms. Xinwei Song
✅ Check out:
Song et al, 2025, Nat. Communications
#Rhizosphere6 #Soil 🧪 🦠 #Arsenic #microbiome
"Rhizosphere-triggered viral #lysogeny mediates microbial
metabolic reprogramming to enhance #arsenic oxidation
» Ms. Xinwei Song
✅ Check out:
Song et al, 2025, Nat. Communications
#Rhizosphere6 #Soil 🧪 🦠 #Arsenic #microbiome
June 18, 2025 at 11:21 AM
Can it be this is the only Rizosphere #Virus talk in the conference?!
"Rhizosphere-triggered viral #lysogeny mediates microbial
metabolic reprogramming to enhance #arsenic oxidation
» Ms. Xinwei Song
✅ Check out:
Song et al, 2025, Nat. Communications
#Rhizosphere6 #Soil 🧪 🦠 #Arsenic #microbiome
"Rhizosphere-triggered viral #lysogeny mediates microbial
metabolic reprogramming to enhance #arsenic oxidation
» Ms. Xinwei Song
✅ Check out:
Song et al, 2025, Nat. Communications
#Rhizosphere6 #Soil 🧪 🦠 #Arsenic #microbiome
Arbitrium systems control lysis/lysogeny through the regulation of small antirepressor proteins https://www.biorxiv.org/content/10.1101/2025.11.23.689978v1
November 25, 2025 at 2:17 AM
Arbitrium systems control lysis/lysogeny through the regulation of small antirepressor proteins https://www.biorxiv.org/content/10.1101/2025.11.23.689978v1
Bacteriophage tRNA-dependent lysogeny: requirement of phage-encoded tRNA genes for establishment of lysogeny
mBio journal by Carlos Guerrero-Bustamante and Graham Hatfull
journals.asm.org/doi/10.1128/...
mBio journal by Carlos Guerrero-Bustamante and Graham Hatfull
journals.asm.org/doi/10.1128/...
January 18, 2024 at 3:03 PM
Bacteriophage tRNA-dependent lysogeny: requirement of phage-encoded tRNA genes for establishment of lysogeny
mBio journal by Carlos Guerrero-Bustamante and Graham Hatfull
journals.asm.org/doi/10.1128/...
mBio journal by Carlos Guerrero-Bustamante and Graham Hatfull
journals.asm.org/doi/10.1128/...
Lysogeny Broth. Jebiga, phage scientist here. A osim toga, tako ga je i Bertani nazvao kad ga je izmislio
www.ncbi.nlm.nih.gov/pmc/articles...
www.ncbi.nlm.nih.gov/pmc/articles...
September 16, 2023 at 6:44 AM
Lysogeny Broth. Jebiga, phage scientist here. A osim toga, tako ga je i Bertani nazvao kad ga je izmislio
www.ncbi.nlm.nih.gov/pmc/articles...
www.ncbi.nlm.nih.gov/pmc/articles...
Cool new Salmonella sRNAs that control phage replication & lysogeny. Nico Wenner will explain all - Poster 196 tomorrow #Microbio17
December 31, 2024 at 12:11 PM
Cool new Salmonella sRNAs that control phage replication & lysogeny. Nico Wenner will explain all - Poster 196 tomorrow #Microbio17
Arbitrium phages can manipulate each other's lysis - lysogeny decisions https://www.biorxiv.org/content/10.1101/2025.10.13.681967v1
October 14, 2025 at 5:32 PM
Arbitrium phages can manipulate each other's lysis - lysogeny decisions https://www.biorxiv.org/content/10.1101/2025.10.13.681967v1
Pretty interesting phage lysogeny during germination of B. subtilis spores
March 24, 2024 at 10:22 AM
Pretty interesting phage lysogeny during germination of B. subtilis spores
Tomorrow would have been the 88th birthday of molecular biologist Maharani Chakravorty, who worked in the fields of protein synthesis, unicellular metabolism, and the biochemistry of cell lysogeny. She passed away in 2015.
#WomenInSTEM #HistSci #BioSky 🧪
#WomenInSTEM #HistSci #BioSky 🧪
February 1, 2025 at 7:26 PM
Tomorrow would have been the 88th birthday of molecular biologist Maharani Chakravorty, who worked in the fields of protein synthesis, unicellular metabolism, and the biochemistry of cell lysogeny. She passed away in 2015.
#WomenInSTEM #HistSci #BioSky 🧪
#WomenInSTEM #HistSci #BioSky 🧪