Lipid transfer proteins are an evolutionary-conserved families of proteins that transfer lipids at sites of contacts between the membrane of distinct organelles and contribute to the regulation of org...

Jean-François Morot-Gaudry (1943–2024): A Life Devoted to Plant Science, Leadership, and Humanity

The plant cell wall regulates development through spatiotemporal modulation of its chemical and mechanical properties. Pectin methylesterification is recognized as a rheological switch controlling wal...

Evolutionary conservation of plant receptor structure allowed for generation of new variants of wheat and barley nucleotide-binding leucine-rich repeat receptors (NLRs) that recognize AvrSr35 of the w...

Transbilayer asymmetry is a structural hallmark of biological membranes. Here, the authors show that phosphoinositide asymmetry represents a key feature facilitating FGF2-induced membrane pore formati...

The emergence of cell compartmentalization depends on membrane fission to create the endomembrane compartments. In eukaryotes, membrane fission is commonly executed by ESCRT-III, a protein complex con...

Through synchronized cargo traffic experiments, the authors explore the role of raft partitioning in ER efflux. Raft-preferring cargos show specific preferences for ER exit sites and exit faster than ...

Nature Communications - Through synchronized cargo traffic experiments, the authors explore the role of raft partitioning in ER efflux. Raft-preferring cargos show specific preferences for ER exit...

The early 20th-century artist Robert Delaunay began painting at a pivotal moment in art history, namely during the chemical industry revolution, when the number of pigments available on the market increased. Today scientists are trying to solve the mystery of the painter’s colours, his purples in particular. One of the objectives of this research is to generate knowledge essential to conserving the works.

Léna, cinq ans, pose la question au micro des P’tits bateaux. Et c’est le chercheur François Parcy, spécialiste des fleurs, qui lui répond et lui décrit cette énorme plante que l'on retrouve dans les ...

The ER exit site is a portal on the endoplasmic reticulum where secretory proteins depart. Here, the authors revealed that a balanced phosphorylation state of the ER exit site proteins TANGO1 and Sec1...

La science ouverte va-t-elle prendre un nouveau tournant à l’heure d’un contexte international tendu et d’une IA en plein essor pour le meilleur comme pour le

Is open science on the cusp of taking a new turn in the current context of international tension twinned with AI's rapid rise, for better or for worse?

Epithelial cell polarization is essential for many physiological processes, including tissue morphogenesis, nutrient absorption, barrier integrity, and directional secretion. A defining feature of suc...

Bruno Guillotin has joined the IPS2 unit (Institute of Plant Sciences Paris-Saclay) as a CNRS Research Scientist. He was recruited in February 2025.   After studying Plant Biology and Physiology, he completed his PhD between 2013 and 2016 at the Plant Science Research Laboratory (LRSV – Toulouse) under the supervision of Guillaume Bécard and Jean-Philippe Combier. His doctoral work focused on the autoregulation of arbuscular mycorrhizal symbiosis in Medicago truncatula.   Following his PhD, he turned his attention to the study of root development in various plant species as a postdoctoral researcher in Kenneth Birnbaum’s group at New York University. There, supported by a Human Frontiers Long-Term Fellowship, he developed numerous protocols for single-cell transcriptomics (single-cell RNA-seq), which he implemented to study gene evolution across agronomically relevant species (maize, sorghum, millet), as well as to investigate cell regeneration in the roots of Arabidopsis thaliana.   In 2025, he was appointed as a CNRS Research Scientist and was also awarded the CNRS–INSERM ATIP-Avenir grant. At IPS2, Bruno Guillotin’s research focuses on understanding how plant cells communicate through plasmodesmata, aiming to identify which proteins and peptides move from one cell to another and contribute to organ morphogenesis in plants. His work combines single-cell RNA-seq, proteomics, genomics, and bioinformatics approaches.   Contact email : [email protected]