Structure-informed phylogenetic inference with FoldTree outperforms sequence-only trees on divergent proteins, and untangles RRNPPA quorum-sensing receptors across Gram-positive bacteria & phages. Work led by David Moi (www.linkedin.com/in/david-moi) Paper: doi.org/10.1038/s415...
October 23, 2025 at 6:13 AM
Structure-informed phylogenetic inference with FoldTree outperforms sequence-only trees on divergent proteins, and untangles RRNPPA quorum-sensing receptors across Gram-positive bacteria & phages. Work led by David Moi (www.linkedin.com/in/david-moi) Paper: doi.org/10.1038/s415...
Effectors weren't uniformly deployed across hosts. Minc18636, tested by Nguyen et al. 2018, showed no loss of virulence on tomato when silenced, and - surprisingly- was lowly expressed in my dataset. Silencing it did impact parasitism on Medicago. This is really exciting!
September 30, 2025 at 12:06 PM
Effectors weren't uniformly deployed across hosts. Minc18636, tested by Nguyen et al. 2018, showed no loss of virulence on tomato when silenced, and - surprisingly- was lowly expressed in my dataset. Silencing it did impact parasitism on Medicago. This is really exciting!
Our data show that the phylogenetic distance of plants did not influence the phenotype or transcriptome profile of Mincognita. More striking, we show that there is essentially no widespread core gall transcriptome at 25 dpi, prompting the proposal of a model best described as all roads lead to Rome
September 30, 2025 at 12:06 PM
Our data show that the phylogenetic distance of plants did not influence the phenotype or transcriptome profile of Mincognita. More striking, we show that there is essentially no widespread core gall transcriptome at 25 dpi, prompting the proposal of a model best described as all roads lead to Rome
Despite their differences, they share a similar regulatory network with lateral root development. This highlights the plasticity of plants and also how other organisms adapted to induce such remarkable changes in their tissues.
June 20, 2025 at 11:19 AM
Despite their differences, they share a similar regulatory network with lateral root development. This highlights the plasticity of plants and also how other organisms adapted to induce such remarkable changes in their tissues.
We explore how plants adapt their developmental programs to form specialized organs — nodules, galls, haustoria — enabling mutualistic or parasitic symbioses. Despite their differences, these organs share gene regulatory pathways, demonstrating the remarkable plasticity of plant development.
June 20, 2025 at 8:23 AM
We explore how plants adapt their developmental programs to form specialized organs — nodules, galls, haustoria — enabling mutualistic or parasitic symbioses. Despite their differences, these organs share gene regulatory pathways, demonstrating the remarkable plasticity of plant development.