Vincent Aucagne
@ucagne.bsky.social
Synthetic organic chemist and chemical biologist @CNRS
Reposted by Vincent Aucagne
Very happy to share our collaborative project on FAM118 proteins - noncanonical sirtuins that form filaments and process NAD in human and other vertebrate cells.
Filament formation and NAD processing by noncanonical human FAM118 sirtuins
Nature Structural & Molecular Biology - Baretić and Missoury et al. identify vertebrate proteins FAM118B and FAM118A as sirtuins similar to bacterial antiphage enzymes and show that...
rdcu.be
November 17, 2025 at 11:37 AM
Very happy to share our collaborative project on FAM118 proteins - noncanonical sirtuins that form filaments and process NAD in human and other vertebrate cells.
Reposted by Vincent Aucagne
SUMO interactions: the 1st of two reviews which Aanchal (@origichals.bsky.social), El Hadji, and I have recently written on non-covalent interactions of SUMO is now out. The 1st covers interactions with E1, E2, and deSUMOylating enzymes; the 2nd - on interactions with SIMs etc. - will appear soon.
Non-covalent SUMO interactions with (de)conjugation enzymes
SUMOylation – a protein post-translational modification (PTM) related to ubiquitylation – involves the reversible covalent attachment of the small ubiquitin-like modifier (SUMO) to proteins. During th...
portlandpress.com
November 5, 2025 at 1:44 PM
SUMO interactions: the 1st of two reviews which Aanchal (@origichals.bsky.social), El Hadji, and I have recently written on non-covalent interactions of SUMO is now out. The 1st covers interactions with E1, E2, and deSUMOylating enzymes; the 2nd - on interactions with SIMs etc. - will appear soon.
Reposted by Vincent Aucagne
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Profiling the proteome-wide selectivity of diverse electrophiles - Nature Chemistry
Covalent inhibitors are powerful entities in drug discovery. Now the amino acid selectivity and reactivity of a diverse electrophile library have been assessed proteome-wide using an unbiased workflow...
www.nature.com
October 30, 2025 at 10:27 AM
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Reposted by Vincent Aucagne
A big thank you to all the speakers, poster presenters, volunteers, chairs, exhibitors, sponsors, and participants who made the conference #ChemBioParis2025 such a success!
@icbschembio.bsky.social
@euchem.bsky.social
@eu-openscreen.bsky.social
#ChemBio
@icbschembio.bsky.social
@euchem.bsky.social
@eu-openscreen.bsky.social
#ChemBio
Feeling grateful after an extraordinary #ChemBioParis2025.
Thanks to all keynotes, speakers, trainees, organizers, volunteers, sponsors, and exhibitors for uniting science and spirit in Paris.
The conversations, discoveries, and friendships this week remind us why we love chemical biology. 💫🔬
Thanks to all keynotes, speakers, trainees, organizers, volunteers, sponsors, and exhibitors for uniting science and spirit in Paris.
The conversations, discoveries, and friendships this week remind us why we love chemical biology. 💫🔬
October 14, 2025 at 1:46 PM
A big thank you to all the speakers, poster presenters, volunteers, chairs, exhibitors, sponsors, and participants who made the conference #ChemBioParis2025 such a success!
@icbschembio.bsky.social
@euchem.bsky.social
@eu-openscreen.bsky.social
#ChemBio
@icbschembio.bsky.social
@euchem.bsky.social
@eu-openscreen.bsky.social
#ChemBio
Reposted by Vincent Aucagne
Feeling grateful after an extraordinary #ChemBioParis2025.
Thanks to all keynotes, speakers, trainees, organizers, volunteers, sponsors, and exhibitors for uniting science and spirit in Paris.
The conversations, discoveries, and friendships this week remind us why we love chemical biology. 💫🔬
Thanks to all keynotes, speakers, trainees, organizers, volunteers, sponsors, and exhibitors for uniting science and spirit in Paris.
The conversations, discoveries, and friendships this week remind us why we love chemical biology. 💫🔬
October 14, 2025 at 11:19 AM
Feeling grateful after an extraordinary #ChemBioParis2025.
Thanks to all keynotes, speakers, trainees, organizers, volunteers, sponsors, and exhibitors for uniting science and spirit in Paris.
The conversations, discoveries, and friendships this week remind us why we love chemical biology. 💫🔬
Thanks to all keynotes, speakers, trainees, organizers, volunteers, sponsors, and exhibitors for uniting science and spirit in Paris.
The conversations, discoveries, and friendships this week remind us why we love chemical biology. 💫🔬
Reposted by Vincent Aucagne
I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.
September 5, 2025 at 5:41 AM
I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.
Reposted by Vincent Aucagne
Excited to share our latest: we engineered the reactivity of a bacterial E1-like enzyme for ATP-driven modification of C termini. Our tool mimics the logic of peptide bond formation in biology for precision modification of proteins in vitro. 🧪https://rdcu.be/ewN7C
Engineered reactivity of a bacterial E1-like enzyme enables ATP-driven modification of protein and peptide C termini
Nature Chemistry - In living systems, ATP provides an energetic driving force for protein synthesis and modification. Now, an engineered enzymatic tool has been developed for high-yield, ATP-driven...
rdcu.be
July 18, 2025 at 2:40 PM
Excited to share our latest: we engineered the reactivity of a bacterial E1-like enzyme for ATP-driven modification of C termini. Our tool mimics the logic of peptide bond formation in biology for precision modification of proteins in vitro. 🧪https://rdcu.be/ewN7C
Reposted by Vincent Aucagne
⚠️ Seats are going fast!
#ChemBioParis2025 is almost sold out.
Join the biggest event ever in chemical biology — or risk missing out.
🗓️ Oct 6–9 | Paris
🎟️ Register now: chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025 #ScienceConference
#ChemBioParis2025 is almost sold out.
Join the biggest event ever in chemical biology — or risk missing out.
🗓️ Oct 6–9 | Paris
🎟️ Register now: chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025 #ScienceConference
June 29, 2025 at 11:19 AM
⚠️ Seats are going fast!
#ChemBioParis2025 is almost sold out.
Join the biggest event ever in chemical biology — or risk missing out.
🗓️ Oct 6–9 | Paris
🎟️ Register now: chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025 #ScienceConference
#ChemBioParis2025 is almost sold out.
Join the biggest event ever in chemical biology — or risk missing out.
🗓️ Oct 6–9 | Paris
🎟️ Register now: chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025 #ScienceConference
Reposted by Vincent Aucagne
⏳ Imagine it’s 22:07 on June 24...
You’ve got less than 2 hours to:
💳 Lock in early-bird registration
📝 Submit your abstract
🎯 Or… miss the deadline, and pay €100 more to register.
⚠️ No extensions. No second chances.
Avoid the stress — do it now → chembioparis2025.com
#ChemBioParis2025
You’ve got less than 2 hours to:
💳 Lock in early-bird registration
📝 Submit your abstract
🎯 Or… miss the deadline, and pay €100 more to register.
⚠️ No extensions. No second chances.
Avoid the stress — do it now → chembioparis2025.com
#ChemBioParis2025
June 22, 2025 at 8:07 AM
⏳ Imagine it’s 22:07 on June 24...
You’ve got less than 2 hours to:
💳 Lock in early-bird registration
📝 Submit your abstract
🎯 Or… miss the deadline, and pay €100 more to register.
⚠️ No extensions. No second chances.
Avoid the stress — do it now → chembioparis2025.com
#ChemBioParis2025
You’ve got less than 2 hours to:
💳 Lock in early-bird registration
📝 Submit your abstract
🎯 Or… miss the deadline, and pay €100 more to register.
⚠️ No extensions. No second chances.
Avoid the stress — do it now → chembioparis2025.com
#ChemBioParis2025
Reposted by Vincent Aucagne
🧪 Just 7 days left!
Early bird & abstract deadline for #ChemBioParis2025 is June 24 (Paris time).
⚠️ No extension this time — don’t miss it.
📍 Paris | 🗓 Oct 6–9, 2025
🔗 chembioparis2025.com
#ChemicalBiology #DrugDiscovery #DeadlineAlert
Early bird & abstract deadline for #ChemBioParis2025 is June 24 (Paris time).
⚠️ No extension this time — don’t miss it.
📍 Paris | 🗓 Oct 6–9, 2025
🔗 chembioparis2025.com
#ChemicalBiology #DrugDiscovery #DeadlineAlert
June 17, 2025 at 8:36 PM
🧪 Just 7 days left!
Early bird & abstract deadline for #ChemBioParis2025 is June 24 (Paris time).
⚠️ No extension this time — don’t miss it.
📍 Paris | 🗓 Oct 6–9, 2025
🔗 chembioparis2025.com
#ChemicalBiology #DrugDiscovery #DeadlineAlert
Early bird & abstract deadline for #ChemBioParis2025 is June 24 (Paris time).
⚠️ No extension this time — don’t miss it.
📍 Paris | 🗓 Oct 6–9, 2025
🔗 chembioparis2025.com
#ChemicalBiology #DrugDiscovery #DeadlineAlert
Reposted by Vincent Aucagne
We have another postdoc position available to work on interplay between ADP-ribosylation and ubiquitination in regulation of genome stability. For this post expertise in cell biology is required.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
'
my.corehr.com
June 6, 2025 at 4:48 AM
We have another postdoc position available to work on interplay between ADP-ribosylation and ubiquitination in regulation of genome stability. For this post expertise in cell biology is required.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Reposted by Vincent Aucagne
⏳ Don’t miss out!
Early bird registration for #ChemBioParis2025 closes on June 10 🐦
Secure your spot now for reduced rates and join us in Paris for an exciting scientific program! 🇫🇷
🔗 chembioparis2025.com
#ChemBioEvent #ICBS2025 #ECBS2025
Early bird registration for #ChemBioParis2025 closes on June 10 🐦
Secure your spot now for reduced rates and join us in Paris for an exciting scientific program! 🇫🇷
🔗 chembioparis2025.com
#ChemBioEvent #ICBS2025 #ECBS2025
June 5, 2025 at 11:19 AM
⏳ Don’t miss out!
Early bird registration for #ChemBioParis2025 closes on June 10 🐦
Secure your spot now for reduced rates and join us in Paris for an exciting scientific program! 🇫🇷
🔗 chembioparis2025.com
#ChemBioEvent #ICBS2025 #ECBS2025
Early bird registration for #ChemBioParis2025 closes on June 10 🐦
Secure your spot now for reduced rates and join us in Paris for an exciting scientific program! 🇫🇷
🔗 chembioparis2025.com
#ChemBioEvent #ICBS2025 #ECBS2025
Reposted by Vincent Aucagne
🎉 The #ChemBioParis2025 scientific program is now online!
Check it out, register, and don’t forget to submit your abstract by June 10!
🔗 chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025
@icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social
Check it out, register, and don’t forget to submit your abstract by June 10!
🔗 chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025
@icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social
ChemBioParis2025 | Approaching Biology through Chemistry
The International Chemical Biology Society, the EuChemS Division of Chemical Biology and Chemistry in Life Sciences, EU-OPENSCREEN and SCF-ChemBio are pleased to announce that the ChemBioParis, a…
chembioparis2025.com
May 28, 2025 at 11:19 AM
🎉 The #ChemBioParis2025 scientific program is now online!
Check it out, register, and don’t forget to submit your abstract by June 10!
🔗 chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025
@icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social
Check it out, register, and don’t forget to submit your abstract by June 10!
🔗 chembioparis2025.com
#ChemicalBiology #ICBS2025 #ECBS2025
@icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social
Reposted by Vincent Aucagne
We are thrilled to welcome @alessiociulli.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
May 27, 2025 at 11:19 AM
We are thrilled to welcome @alessiociulli.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
Reposted by Vincent Aucagne
A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for someone with experience in structural biology and biochemistry. The application deadline is June 20th.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
'
my.corehr.com
May 24, 2025 at 5:29 AM
A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for someone with experience in structural biology and biochemistry. The application deadline is June 20th.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Reposted by Vincent Aucagne
🌍 Last week of reduced fees to be part of the global spotlight at #ChemBioParis2025 — the premier Chemical Biology event of 2025 at Sorbonne Université, Paris.
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Hurry to get a partnership kit: chembioparis2025.com
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Hurry to get a partnership kit: chembioparis2025.com
May 26, 2025 at 11:19 AM
🌍 Last week of reduced fees to be part of the global spotlight at #ChemBioParis2025 — the premier Chemical Biology event of 2025 at Sorbonne Université, Paris.
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Hurry to get a partnership kit: chembioparis2025.com
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Hurry to get a partnership kit: chembioparis2025.com
Reposted by Vincent Aucagne
We are thrilled to welcome Matthew Disney at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
May 22, 2025 at 11:19 AM
We are thrilled to welcome Matthew Disney at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
Reposted by Vincent Aucagne
We are thrilled to welcome Yimon Aye at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
May 20, 2025 at 11:19 AM
We are thrilled to welcome Yimon Aye at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
Reposted by Vincent Aucagne
We are thrilled to welcome Daniel Nomura at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
May 15, 2025 at 11:19 AM
We are thrilled to welcome Daniel Nomura at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
Reposted by Vincent Aucagne
We are thrilled to welcome @hargrovelab.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
May 8, 2025 at 11:19 AM
We are thrilled to welcome @hargrovelab.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
Reposted by Vincent Aucagne
🌍 Be part of the global spotlight at #ChemBioParis2025 — the premier Chemical Biology event of 2025 at Sorbonne Université, Paris.
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Get our partnership kit: chembioparis2025.com
#ICBS2025 #ECBS2025 #ChemBio
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Get our partnership kit: chembioparis2025.com
#ICBS2025 #ECBS2025 #ChemBio
May 9, 2025 at 12:20 PM
🌍 Be part of the global spotlight at #ChemBioParis2025 — the premier Chemical Biology event of 2025 at Sorbonne Université, Paris.
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Get our partnership kit: chembioparis2025.com
#ICBS2025 #ECBS2025 #ChemBio
💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists!
📩 Get our partnership kit: chembioparis2025.com
#ICBS2025 #ECBS2025 #ChemBio
Reposted by Vincent Aucagne
We are thrilled to welcome @christhechang.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
May 6, 2025 at 11:19 AM
We are thrilled to welcome @christhechang.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent
Reposted by Vincent Aucagne
📢 Registration is NOW OPEN for ICBS / ECBS 2025!
🔗 chembioparis2025.com
📍 Paris, France
📅 October 6–9, 2025
Join us for the premier event in chemical biology 🌍🧪
#ICBS2025 #ECBS2025 #ChemBioParis2025 #ChemicalBiology
🔗 chembioparis2025.com
📍 Paris, France
📅 October 6–9, 2025
Join us for the premier event in chemical biology 🌍🧪
#ICBS2025 #ECBS2025 #ChemBioParis2025 #ChemicalBiology
May 5, 2025 at 11:00 AM
📢 Registration is NOW OPEN for ICBS / ECBS 2025!
🔗 chembioparis2025.com
📍 Paris, France
📅 October 6–9, 2025
Join us for the premier event in chemical biology 🌍🧪
#ICBS2025 #ECBS2025 #ChemBioParis2025 #ChemicalBiology
🔗 chembioparis2025.com
📍 Paris, France
📅 October 6–9, 2025
Join us for the premier event in chemical biology 🌍🧪
#ICBS2025 #ECBS2025 #ChemBioParis2025 #ChemicalBiology
Reposted by Vincent Aucagne
#ChemBioParis2025 is THE hub for networking & advancing chemical biology! 🚀 Don’t miss this chance to connect with global leaders & rising stars. Secure your spot: chembioparis2025.com #ChemBio2025 #ChemicalBiology
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ChemBioParis2025 | Approaching Biology through Chemistry
chembioparis2025.com
May 4, 2025 at 7:13 PM
#ChemBioParis2025 is THE hub for networking & advancing chemical biology! 🚀 Don’t miss this chance to connect with global leaders & rising stars. Secure your spot: chembioparis2025.com #ChemBio2025 #ChemicalBiology
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Reposted by Vincent Aucagne
Present your work at #ChemBioParis2025! 📊
Submit abstracts by June 10, 2025. Register by June 10 for early bird discounts. Be part of this chemical biology milestone in Paris! chembioparis2025.com #ICBS2025 #ECBS2025
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Submit abstracts by June 10, 2025. Register by June 10 for early bird discounts. Be part of this chemical biology milestone in Paris! chembioparis2025.com #ICBS2025 #ECBS2025
[6/7]
ChemBioParis2025 | Approaching Biology through Chemistry
chembioparis2025.com
May 4, 2025 at 7:13 PM
Present your work at #ChemBioParis2025! 📊
Submit abstracts by June 10, 2025. Register by June 10 for early bird discounts. Be part of this chemical biology milestone in Paris! chembioparis2025.com #ICBS2025 #ECBS2025
[6/7]
Submit abstracts by June 10, 2025. Register by June 10 for early bird discounts. Be part of this chemical biology milestone in Paris! chembioparis2025.com #ICBS2025 #ECBS2025
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