Engelhardt Research Group
@thebeehive.bsky.social
Engelhardt Research Group at Stanford University and Gladstone Institutes. Statistical genomics, live-cell imaging, wearable data, cancer immunology, reproductive health.
Super excited to tell you about our preprint on Neighborhood Nonnegative Matrix Factorization (NNMF) for spatially-aware dimension reduction in spatial transcriptomics, led by Ragnhild Laursen in collaboration with Karin Pelka @pelkalab.bsky.social and her lab!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Neighborhood nonnegative matrix factorization identifies patterns and spatially-variable genes in large-scale spatial transcriptomics data
Tissues consist of multi-cellular neighborhoods in which different cell types express correlated gene programs due to shared signaling environments. Methods for identifying these spatial neighborhoods...
www.biorxiv.org
April 29, 2025 at 10:21 PM
Super excited to tell you about our preprint on Neighborhood Nonnegative Matrix Factorization (NNMF) for spatially-aware dimension reduction in spatial transcriptomics, led by Ragnhild Laursen in collaboration with Karin Pelka @pelkalab.bsky.social and her lab!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Exciting update!! @bioimagearchive.bsky.social is now hosting the first publicly available Incucyte data! If you have live-cell imaging data, please consider uploading to this amazing repository!! Thanks to Julia Carnevale and Alex Marson for experimental data —
www.ebi.ac.uk/biostudies/b...
www.ebi.ac.uk/biostudies/b...
January 21, 2025 at 1:33 AM
Exciting update!! @bioimagearchive.bsky.social is now hosting the first publicly available Incucyte data! If you have live-cell imaging data, please consider uploading to this amazing repository!! Thanks to Julia Carnevale and Alex Marson for experimental data —
www.ebi.ac.uk/biostudies/b...
www.ebi.ac.uk/biostudies/b...
First post in the Good Place! Our preprint on cellular behavior analysis in TCR T cells & cancer cell live-cell imaging data is out! This 3-year collaboration led by pd Archit Verma w/ Alex Marson & Julia Carnevale, with segmentation & tracking by @davidvv & team! www.biorxiv.org/content/10.1...
Cellular behavior analysis from live-cell imaging of TCR T cell–cancer cell interactions
T cell therapies, such as chimeric antigen receptor (CAR) T cells and T cell receptor (TCR) T cells, are a growing class of anti-cancer treatments. However, expansion to novel indications and beyond l...
www.biorxiv.org
November 26, 2024 at 2:01 AM
First post in the Good Place! Our preprint on cellular behavior analysis in TCR T cells & cancer cell live-cell imaging data is out! This 3-year collaboration led by pd Archit Verma w/ Alex Marson & Julia Carnevale, with segmentation & tracking by @davidvv & team! www.biorxiv.org/content/10.1...