Sophia Davidson
sciencesophie.bsky.social
Sophia Davidson
@sciencesophie.bsky.social
Innate Immunologist interested in upsetting cells enough to drive inflammation (especially type I Interferons!)
When you complain so much on socials the science man himself, @drshanerrr.bsky.social invites you over for a chat 🤩🤩🤩

#einsteinagogo #3tripleR
October 12, 2025 at 12:01 AM
If you care about the future of Australian health + innovation, please make a submission to #NHMRC

⚔️Protect🛡️discovery science 🔬🧪🤯
🌟Make it a priority and fund it properly🌟

Submissions due this Wednesday, 8th of October: consultations.health.gov.au/health-economi…#ValueFundamentalSciencece
https://consultations.health.gov.au/health-economi…
October 6, 2025 at 9:27 PM
Australia has a vibrant, brilliant discovery science community. It deserves to be nurtured, not left to starve while everything is rebranded “translation.”

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
October 6, 2025 at 9:27 PM
So what changes do I suggest?

🌟Add a specific goal for discovery/basic science

🌟Guarantee a ring-fenced % of funds for it

🌟Block funding for institutes so scientists aren’t living grant to grant

🌟Ensure national platforms are accessible beyond home institutes
October 6, 2025 at 9:27 PM
Don’t get me wrong, I love translational research, I hope my research will one day be translated

I want to see a #NHMRCStratergy that ensures there's Australian grown discoveries to be translated for better health outcomes for all Australians 🌏🇦🇺
October 6, 2025 at 9:27 PM
If we cut discovery science, we cut these returns

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
October 6, 2025 at 9:27 PM
And let’s be clear, funding discovery research is not charity, it's not just about keeping weirdos like me off the streets, IT PAYS FOR ITSELF

AAMRI/KPMG found that every $1 invested in Australian medical research returns $3.90 to the economy
October 6, 2025 at 9:27 PM
👏Translation 👏dries up 👏if you stop feeding 👏the pipeline 👏of discovery👏

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
October 6, 2025 at 9:27 PM
In the 1990s–2000s, Japan and the UK shifted funding away from basic research

Their biomedical sectors became reliant on discoveries made elsewhere, and despite big translational investments💰, patent returns and innovation declined (OECD 2016: bit.ly/3UwzMrv) 💸💸💸
bit.ly
October 6, 2025 at 9:27 PM
You think I’m being dramatic 🎭, but it’s happened before:

OECD’s Science, Tech & Innovation Outlook (2016) found that when countries shifted funding from basic to short-term translational research, high-impact papers and patents declined 👇⏬📉⬇️
October 6, 2025 at 9:27 PM
The discovery of #GMCSF and #IFNε didn't stem from translational projects, hey came from years of scientists chasing fundamental questions

Under the #NHMRCDraftStrategy, research like this will be sidelined… and the next life-changing therapy could be lost before it even begins
October 6, 2025 at 9:27 PM
Another example, close to the #HudsonInstitute’s ❤️ is the discovery of #IFNε, an antiviral cytokine found almost exclusively in the female reproductive tract

Long overlooked, IFNε is now known to play keys role in protection from #ovariancancer and progression of #endometriosis
October 6, 2025 at 9:27 PM
A fun example of this (which is highlighted in the draft strategy) is the discovery of #GMCSF

GM-CSF is now standard care in cancer and bone marrow transplants, but started out as Prof Don Metcalf making a PhD student look for cool new proteins in human urine...
October 6, 2025 at 9:27 PM
Every goal in the #NHMRCdraftStratergy: #translation, #patents, #AI, #resilience, all depend on novel discoveries made through years (sometimes decades) of curiosity driven research 🧪🔬🧫

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience
October 6, 2025 at 9:27 PM
My major note? It completely leaves out fundamental research as a priority 🤯

Which is wild, #NHMRC’s job is to "support the highest-quality research, from 👉BASIC science👈 through to clinical, public health and services research" (NHMRC Corporate Plan: nhmrc.gov.au)
nhmrc.gov.au
October 6, 2025 at 9:27 PM
Professor Si Ming Man, CSL Centenary Fellow and NHMRC Leadership Fellow (ANU), focuses on how innate immune activation protects us from infections and toxins. Prof Man will illuminate his latest findings on innate immune sensing of danger signals and cell death.
May 25, 2025 at 6:39 AM
Professor Kate Schroder, leader of the Inflammasome Lab at IMB (UQ) and a Clarivate Highly Cited Researcher, will excite your academic and practical imagination with TWO talks—on her favourite inflammasomes and her path through academia and industry.
May 25, 2025 at 6:37 AM