Sanjay Narayanaswamy
@sanjay-n.bsky.social
Came for science. Staying for the memes. PhD student at @ulrichtechnau.bsky.social Lab, Uni Wien
Pinned
Happy to be presenting our story on Nematostella self-organization :) tune in if you like to hear what organizes the organizer in cnidarian gastruloids!
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Sanjay Narayanaswamy
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
Reposted by Sanjay Narayanaswamy
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
October 8, 2025 at 5:49 PM
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Reposted by Sanjay Narayanaswamy
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
October 1, 2025 at 6:21 PM
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
Reposted by Sanjay Narayanaswamy
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 24, 2025 at 3:12 PM
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Sanjay Narayanaswamy
Just came back from a great meeting in Tutzing on the biology of basal Metazoa. Excellent talks, fantastic posters and very kind and vital community. Thanks also to our keynote speaker, Cassandra Extavour. She was the highlight of the meeting. Thanks everyone for contributing.
September 27, 2025 at 9:20 PM
Just came back from a great meeting in Tutzing on the biology of basal Metazoa. Excellent talks, fantastic posters and very kind and vital community. Thanks also to our keynote speaker, Cassandra Extavour. She was the highlight of the meeting. Thanks everyone for contributing.
Reposted by Sanjay Narayanaswamy
We are excited to announce the first Western VGZT of Season 7! 🎉
🗓️ Thursday, October 2nd
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
Our speakers:
👉 Antonia Weberling (@a-weberling.bsky.social)
👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)
🗓️ Thursday, October 2nd
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
Our speakers:
👉 Antonia Weberling (@a-weberling.bsky.social)
👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)
September 25, 2025 at 2:17 PM
We are excited to announce the first Western VGZT of Season 7! 🎉
🗓️ Thursday, October 2nd
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
Our speakers:
👉 Antonia Weberling (@a-weberling.bsky.social)
👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)
🗓️ Thursday, October 2nd
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
Our speakers:
👉 Antonia Weberling (@a-weberling.bsky.social)
👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)
Happy to be presenting our story on Nematostella self-organization :) tune in if you like to hear what organizes the organizer in cnidarian gastruloids!
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
September 25, 2025 at 1:41 PM
Happy to be presenting our story on Nematostella self-organization :) tune in if you like to hear what organizes the organizer in cnidarian gastruloids!
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Sanjay Narayanaswamy
Hydra body axis balance: a fight between two transcription factors
This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis:
journals.biologists.com/dev/article/...
This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis:
journals.biologists.com/dev/article/...
September 16, 2025 at 10:27 AM
Hydra body axis balance: a fight between two transcription factors
This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis:
journals.biologists.com/dev/article/...
This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis:
journals.biologists.com/dev/article/...
Reposted by Sanjay Narayanaswamy
We knew that cnidarians have stunning regenerative capacities. But the molecular and cellular mechanisms underlying the self-organization of gastruloids of Nematostella surprised us. A story of cell sorting and Notch signaling. Please check out the work of Sanjay's PhD work: doi.org/10.1101/2025...
September 11, 2025 at 4:16 PM
We knew that cnidarians have stunning regenerative capacities. But the molecular and cellular mechanisms underlying the self-organization of gastruloids of Nematostella surprised us. A story of cell sorting and Notch signaling. Please check out the work of Sanjay's PhD work: doi.org/10.1101/2025...
🚨 Happy to share my PhD work! We set out to find what organizes the organizer in Nematostella gastruloids. While we knew Wnt1/3+ cells confer axial polarity, we identify the role of Notch signaling as partner in crime in polarising these organizers. How does it do it? www.biorxiv.org/cgi/content/...
September 12, 2025 at 4:49 AM
🚨 Happy to share my PhD work! We set out to find what organizes the organizer in Nematostella gastruloids. While we knew Wnt1/3+ cells confer axial polarity, we identify the role of Notch signaling as partner in crime in polarising these organizers. How does it do it? www.biorxiv.org/cgi/content/...
Reposted by Sanjay Narayanaswamy
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...
August 29, 2025 at 9:04 PM
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...
Reposted by Sanjay Narayanaswamy
Great opportunity! The Uni Vienna has launched a call (APART) for 4-funding for outstanding postdocs from a US institution. The host lab has to nominate by 1 August a candidate for further selection. Anyone interested in our work please contact me by email with CV/motivation letter. Hurry up!
July 26, 2025 at 2:30 PM
Great opportunity! The Uni Vienna has launched a call (APART) for 4-funding for outstanding postdocs from a US institution. The host lab has to nominate by 1 August a candidate for further selection. Anyone interested in our work please contact me by email with CV/motivation letter. Hurry up!
Nematostella butt valve!
We thought we were just studying mesoglea biogenesis…Turns out Nematostella has been hiding a sophisticated backup pressure valve! Work driven by the talented PhD student Soham Basu! @embl.org www.biorxiv.org/content/10.1...
May 28, 2025 at 6:57 PM
Nematostella butt valve!
Reposted by Sanjay Narayanaswamy
In which we discuss the homologies between amphibian and mammalian organizers from the perspective of #gastruloids with special relevance to recently described A and C gastruloids as containing Spemann/Mangold and Trunk/Tail organizers www.sciencedirect.com/science/arti...
May 23, 2025 at 10:35 AM
In which we discuss the homologies between amphibian and mammalian organizers from the perspective of #gastruloids with special relevance to recently described A and C gastruloids as containing Spemann/Mangold and Trunk/Tail organizers www.sciencedirect.com/science/arti...
We review self-organisation of organizers through the lens of Cnidarians (primarily Hydra and Nematostella) and propose an integrative Mechanochemical view for the same.
Happy to be part of the 100 year Mangold-Spemann special edition @cellsdev.bsky.social @ulrichtechnau.bsky.social
Happy to be part of the 100 year Mangold-Spemann special edition @cellsdev.bsky.social @ulrichtechnau.bsky.social
About 100 years the Mangold-Spemann organizer was published and this has been one of the most fruitful and inspiring concepts in Developmental Biology. But how can organizers self-organize? In this review we summarize the knowledge how cnidarians do that: doi.org/10.1016/j.cd...
Redirecting
doi.org
May 4, 2025 at 7:05 PM
We review self-organisation of organizers through the lens of Cnidarians (primarily Hydra and Nematostella) and propose an integrative Mechanochemical view for the same.
Happy to be part of the 100 year Mangold-Spemann special edition @cellsdev.bsky.social @ulrichtechnau.bsky.social
Happy to be part of the 100 year Mangold-Spemann special edition @cellsdev.bsky.social @ulrichtechnau.bsky.social
Reposted by Sanjay Narayanaswamy
About 100 years the Mangold-Spemann organizer was published and this has been one of the most fruitful and inspiring concepts in Developmental Biology. But how can organizers self-organize? In this review we summarize the knowledge how cnidarians do that: doi.org/10.1016/j.cd...
Redirecting
doi.org
April 30, 2025 at 12:03 PM
About 100 years the Mangold-Spemann organizer was published and this has been one of the most fruitful and inspiring concepts in Developmental Biology. But how can organizers self-organize? In this review we summarize the knowledge how cnidarians do that: doi.org/10.1016/j.cd...
Reposted by Sanjay Narayanaswamy
Here our model of how LME animal migration ends. I am happy to see this work out! As for cell migration in vivo, the path of this journey hasn’t always been straightforward. It is the closing of a chapter, and I look forward to what the future will bring.
March 12, 2025 at 1:01 PM
Here our model of how LME animal migration ends. I am happy to see this work out! As for cell migration in vivo, the path of this journey hasn’t always been straightforward. It is the closing of a chapter, and I look forward to what the future will bring.
Happy to have presented our evolving story at #DevStem2025. Exciting stuff on the way :)
Kick-off of the late afternoon session at the #DevStem2025 meeting. Sanjay Narayanaswamy @sanjay-n.bsky.social from @ulrichtechnau.bsky.social lab discusses germ layer biology in #Nematostella, exploring a powerful gastruloid system. For a primer on gastruloids, see doi.org/10.1016/j.cd...
April 4, 2025 at 5:21 PM
Happy to have presented our evolving story at #DevStem2025. Exciting stuff on the way :)
Reposted by Sanjay Narayanaswamy
Kick-off of the late afternoon session at the #DevStem2025 meeting. Sanjay Narayanaswamy @sanjay-n.bsky.social from @ulrichtechnau.bsky.social lab discusses germ layer biology in #Nematostella, exploring a powerful gastruloid system. For a primer on gastruloids, see doi.org/10.1016/j.cd...
April 4, 2025 at 3:05 PM
Kick-off of the late afternoon session at the #DevStem2025 meeting. Sanjay Narayanaswamy @sanjay-n.bsky.social from @ulrichtechnau.bsky.social lab discusses germ layer biology in #Nematostella, exploring a powerful gastruloid system. For a primer on gastruloids, see doi.org/10.1016/j.cd...
Reposted by Sanjay Narayanaswamy
We’re looking for PhD students to join the lab! 🧫🧑🔬
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
PhD Program
Empowering Curious Researchers at the Vienna BioCenter PhD Program
Are you a curious and motivated student looking to launch a successful scientific career? Look no further than the Vienna BioCenter P...
training.vbc.ac.at
April 1, 2025 at 1:00 PM
We’re looking for PhD students to join the lab! 🧫🧑🔬
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
Reposted by Sanjay Narayanaswamy
Unexpected role of β-catenin signaling in germ layer specification
In this 'Show and tell' post, @genikhovich.bsky.social and @tclebedeva.bsky.social tell us about their video of a GFP-β-catenin knock-in Nematostella embryo from their latest paper:
🎥 thenode.biologists.com/unexpected-r...
In this 'Show and tell' post, @genikhovich.bsky.social and @tclebedeva.bsky.social tell us about their video of a GFP-β-catenin knock-in Nematostella embryo from their latest paper:
🎥 thenode.biologists.com/unexpected-r...
March 31, 2025 at 3:49 PM
Unexpected role of β-catenin signaling in germ layer specification
In this 'Show and tell' post, @genikhovich.bsky.social and @tclebedeva.bsky.social tell us about their video of a GFP-β-catenin knock-in Nematostella embryo from their latest paper:
🎥 thenode.biologists.com/unexpected-r...
In this 'Show and tell' post, @genikhovich.bsky.social and @tclebedeva.bsky.social tell us about their video of a GFP-β-catenin knock-in Nematostella embryo from their latest paper:
🎥 thenode.biologists.com/unexpected-r...
Beautiful!
And... it's live! In situ hybridization has been foundational for sea urchin developmental biology. Here we report a fully automated method to probe more than a hundred genes using a general purpose liquid handler.https://www.biorxiv.org/content/10.1101/2025.03.23.644641v1
March 25, 2025 at 11:28 PM
Beautiful!
Arguably the most significant step forward in discovery dissemination.
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
March 25, 2025 at 12:11 PM
Arguably the most significant step forward in discovery dissemination.
Reposted by Sanjay Narayanaswamy
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
March 25, 2025 at 11:21 AM
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Reposted by Sanjay Narayanaswamy
How many cells do you need to establish PCP? The magic number is 3! Beautiful work by Lena Basta in Danelle Devenport's lab. Happy to have contributed. www.science.org/doi/10.1126/...
Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous
For cells to polarize collectively along a tissue plane, asymmetrically localized planar cell polarity (PCP) complexes must form intercellular contacts between neighboring cells. Yet, it is unknown wh...
www.science.org
March 22, 2025 at 1:47 AM
How many cells do you need to establish PCP? The magic number is 3! Beautiful work by Lena Basta in Danelle Devenport's lab. Happy to have contributed. www.science.org/doi/10.1126/...