Rob Horne
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robertihorne.bsky.social
Rob Horne
@robertihorne.bsky.social
890 followers 1.4K following 16 posts
Drug discovery fellow @ D. E. Shaw Research focusing on cancer treatments 🧫 PhD from Uni of Cambridge working on inhibitors of neurodegenerative disease 🧠
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Reposted by Rob Horne
fly-broadcast.bsky.social
Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay
#Drosophila
Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
September 18, 2025 at 5:23 PM
Reposted by Rob Horne
aixbiobot.bsky.social
Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay [new]
Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay Figure 1 Figure 2 Figure 3
March 14, 2025 at 10:02 PM
robertihorne.bsky.social
Happy to have been able to contribute to this! @natcomms.nature.com

www.nature.com/articles/s41...
Sequence-based virtual screening using transformers - Nature Communications
Ligand-Transformer is a deep learning framework that predicts protein–ligand binding and conformational changes using only sequence and 2D-structure inputs, enabling efficient virtual screening and un...
www.nature.com
July 29, 2025 at 2:52 AM
robertihorne.bsky.social
New paper from @deshawresearch.com #cancer #vaccines

www.nature.com/articles/s41...
Design of immunogens to present a tumor-specific cryptic epitope - Scientific Reports
Scientific Reports - Design of immunogens to present a tumor-specific cryptic epitope
www.nature.com
April 3, 2025 at 1:21 AM
Reposted by Rob Horne
robertihorne.bsky.social
Would you like to learn about a cutting edge diagnostic/characterisation technique for #neurodegenerative disease? Check out our review here! @sarahesandler.bsky.social @natrevchem.bsky.social
@wyssinstitute.bsky.social
@chemlibcam.bsky.social
#nanopore

Full text: rdcu.be/ech4q
Detection of protein oligomers with nanopores  - Nature Reviews Chemistry
An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other emerging technologies including de...
www.nature.com
March 5, 2025 at 4:50 PM
Reposted by Rob Horne
natrevchem.nature.com
Meditations on mentorship and legacy
Nature Reviews Chemistry, Published online: 13 March 2025; doi:10.1038/s41570-025-00708-4Mary Garson is an Emerita Professor of the University of Queensland and President-elect of the International Union of Pure and Applied Chemistry (IUPAC). In 2024, The…
bit.ly
March 14, 2025 at 3:24 AM
Reposted by Rob Horne
deshawresearch.com
We welcome summer intern applications from undergrad and grad students for our CS, ML, and biochemistry efforts to work on projects such as developing ML models for drug discovery, ML kernels/infrastructure, and large-scale data management/analysis code. apply.deshawresearch.com/careers/Regi...
March 12, 2025 at 1:44 PM
Reposted by Rob Horne
natrevchem.nature.com
Detection of protein oligomers with nanopores

nature.com/articles/s41...

A new Review from @robertihorne.bsky.social @sarahesandler.bsky.social Michele Vendruscolo & Ulrich F. Keyser
Detection of protein oligomers with nanopores  - Nature Reviews Chemistry
An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other emerging technologies including de...
nature.com
March 6, 2025 at 1:56 PM
Reposted by Rob Horne
natrevchem.nature.com
Detection of protein oligomers with nanopores 
Nature Reviews Chemistry, Published online: 05 March 2025; doi:10.1038/s41570-025-00694-7An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other…
bit.ly
March 5, 2025 at 9:49 PM
robertihorne.bsky.social
Would you like to learn about a cutting edge diagnostic/characterisation technique for #neurodegenerative disease? Check out our review here! @sarahesandler.bsky.social @natrevchem.bsky.social
@wyssinstitute.bsky.social
@chemlibcam.bsky.social
#nanopore

Full text: rdcu.be/ech4q
Detection of protein oligomers with nanopores  - Nature Reviews Chemistry
An overview of the progress and potential of nanopore-based detection of oligomerizing proteins is presented, covering the latest advances and combination with other emerging technologies including de...
www.nature.com
March 5, 2025 at 4:50 PM
robertihorne.bsky.social
@srijitseal.com hey could you add me to the cheminformatics starter you set up?
November 30, 2024 at 5:52 PM
robertihorne.bsky.social
@pkpd-babe.bsky.social
Could I be added to Scientists + Clinicians in Neurodegeneration please?
November 30, 2024 at 5:46 PM