Quantum Alchemist
@quantum-alchemist.bsky.social
Lapsed organic chemist. Core instrumentation lab director. I love science, technology, and ingenious solutions to problems great and small.
Long time no post and this is very off topic, but I have to give respect to the people assembling these G502X mice for Logitech. Most mice have electronics on the shell. Here we’ve got everything on a central frame and the buttons weave through that frame. Some of my instruments are simpler.
July 31, 2025 at 4:21 PM
Long time no post and this is very off topic, but I have to give respect to the people assembling these G502X mice for Logitech. Most mice have electronics on the shell. Here we’ve got everything on a central frame and the buttons weave through that frame. Some of my instruments are simpler.
Reposted by Quantum Alchemist
For International Women's Day, here are twelve more women from chemistry history, with achievements ranging from developing antifungal medicines to creating milk substitutes for people with lactose intolerance 👩🏽🔬👩🏻🔬
www.compoundchem.com/2025/03/07/i...
#IWD2025 #ChemSky 🧪
www.compoundchem.com/2025/03/07/i...
#IWD2025 #ChemSky 🧪
March 8, 2025 at 9:39 AM
For International Women's Day, here are twelve more women from chemistry history, with achievements ranging from developing antifungal medicines to creating milk substitutes for people with lactose intolerance 👩🏽🔬👩🏻🔬
www.compoundchem.com/2025/03/07/i...
#IWD2025 #ChemSky 🧪
www.compoundchem.com/2025/03/07/i...
#IWD2025 #ChemSky 🧪
Reposted by Quantum Alchemist
Reddit: Iowa State Chemistry withdrawing international PhD admissions
chemsky 🧪⚗️
www.reddit.com/r/gradadmiss...
chemsky 🧪⚗️
www.reddit.com/r/gradadmiss...
EunochRon's comment on "Offer Withdrawal!! What the actual hell is this??!!!!💀💀"
Explore this conversation and more from the gradadmissions community
www.reddit.com
March 6, 2025 at 10:17 PM
Reddit: Iowa State Chemistry withdrawing international PhD admissions
chemsky 🧪⚗️
www.reddit.com/r/gradadmiss...
chemsky 🧪⚗️
www.reddit.com/r/gradadmiss...
Reposted by Quantum Alchemist
This new piece showcases 100 natural products. Many of the syntheses of these compounds have had significant impacts in organic synthesis.
There are many different structural and functional motifs that have required amazing innovations in synthesis. And one of mine is in there too! #chemsky #sciart
There are many different structural and functional motifs that have required amazing innovations in synthesis. And one of mine is in there too! #chemsky #sciart
March 6, 2025 at 2:36 PM
Reposted by Quantum Alchemist
18F was doing exactly the type of work that DOGE claims to want – yet we were eliminated shortly after midnight. Read our letter to the American people:
18f.org
18f.org
We're not done yet | 18F
18f.org
March 1, 2025 at 11:38 PM
18F was doing exactly the type of work that DOGE claims to want – yet we were eliminated shortly after midnight. Read our letter to the American people:
18f.org
18f.org
Reposted by Quantum Alchemist
Reposted by Quantum Alchemist
#Medsky
🧪
Great news.
I remember when the family with a mutation in a sodium channel was discovered.
This follows my general rule: it often takes 25 years to go from new mechanistic discovery to first approved medicine.
Drug development is HARD
🧪
Great news.
I remember when the family with a mutation in a sodium channel was discovered.
This follows my general rule: it often takes 25 years to go from new mechanistic discovery to first approved medicine.
Drug development is HARD
On Thursday, the US Food and Drug Administration approved suzetrigine for short-term pain management, making it the first non-opioid pain drug given a regulatory nod in more than 20 years.
https://go.nature.com/40SKITt
https://go.nature.com/40SKITt
US drug agency approves potent painkiller — the first non-opioid in decades
The FDA’s nod for suzetrigine bolsters confidence in the pharmaceutical industry’s strategy to target sodium channels.
go.nature.com
January 31, 2025 at 12:47 PM
#Medsky
🧪
Great news.
I remember when the family with a mutation in a sodium channel was discovered.
This follows my general rule: it often takes 25 years to go from new mechanistic discovery to first approved medicine.
Drug development is HARD
🧪
Great news.
I remember when the family with a mutation in a sodium channel was discovered.
This follows my general rule: it often takes 25 years to go from new mechanistic discovery to first approved medicine.
Drug development is HARD
Reposted by Quantum Alchemist
Saddened to learn today of Martin Karplus’ passing over the weekend. He was an absolute luminary and founding force in computational chemistry and biophysics. His influence will be felt for many generations of scientists. May he rest in peace.
#chemsky #compchemsky
#chemsky #compchemsky
December 31, 2024 at 11:38 PM
Saddened to learn today of Martin Karplus’ passing over the weekend. He was an absolute luminary and founding force in computational chemistry and biophysics. His influence will be felt for many generations of scientists. May he rest in peace.
#chemsky #compchemsky
#chemsky #compchemsky
TIL there are automated melting point apparatus. And here I thought I was fancy because ours had a built in oil bath and a vintage mercury thermometer.
Has anyone in #chemsky had luck with buying an automated melting point apparatus? I keep thinking about getting one, and then back off at the price tag. If you have recommendations, or hate them, let me know!
December 17, 2024 at 3:48 AM
TIL there are automated melting point apparatus. And here I thought I was fancy because ours had a built in oil bath and a vintage mercury thermometer.
Reposted by Quantum Alchemist
I wanna do a natural products piece of art. What are your favorite natural products or total syntheses?
I love the sesquiterpines from Maimone, pleuromutilin from Reisman, ryanodol from Inoue, axinellamines from Baran, and ET-743 from Fukuyama #ChemSky
I love the sesquiterpines from Maimone, pleuromutilin from Reisman, ryanodol from Inoue, axinellamines from Baran, and ET-743 from Fukuyama #ChemSky
December 16, 2024 at 8:49 PM
I wanna do a natural products piece of art. What are your favorite natural products or total syntheses?
I love the sesquiterpines from Maimone, pleuromutilin from Reisman, ryanodol from Inoue, axinellamines from Baran, and ET-743 from Fukuyama #ChemSky
I love the sesquiterpines from Maimone, pleuromutilin from Reisman, ryanodol from Inoue, axinellamines from Baran, and ET-743 from Fukuyama #ChemSky
Reposted by Quantum Alchemist
Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the #ChemSky community - more to follow soon!
December 10, 2024 at 1:54 PM
Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the #ChemSky community - more to follow soon!
Beats egg nog every time.
Day 7 of #ChemAdvent24 🍷
Mulled wine contains several spices, including cloves, nutmeg and cinnamon. Cinnamon contains cinnamaldehyde, which is antimicrobial, the eugenol in cloves is mildly anaesthetic, and nutmeg contains myristicin, which is hallucinogenic in very high doses. Quite the cocktail!
Mulled wine contains several spices, including cloves, nutmeg and cinnamon. Cinnamon contains cinnamaldehyde, which is antimicrobial, the eugenol in cloves is mildly anaesthetic, and nutmeg contains myristicin, which is hallucinogenic in very high doses. Quite the cocktail!
December 7, 2024 at 2:06 PM
Beats egg nog every time.
Reposted by Quantum Alchemist
Not being a lawyer, I never thought I'd have to correct an error in one of my favorite podcasts, @strictscrutiny.bsky.social , but oh well!
S6E10 "Gender-affirming care in the court" had an error that stopped me on my dog walk and there's a great American story in the correction.
#biosky #chemsky /1
S6E10 "Gender-affirming care in the court" had an error that stopped me on my dog walk and there's a great American story in the correction.
#biosky #chemsky /1
December 5, 2024 at 6:21 PM
Not being a lawyer, I never thought I'd have to correct an error in one of my favorite podcasts, @strictscrutiny.bsky.social , but oh well!
S6E10 "Gender-affirming care in the court" had an error that stopped me on my dog walk and there's a great American story in the correction.
#biosky #chemsky /1
S6E10 "Gender-affirming care in the court" had an error that stopped me on my dog walk and there's a great American story in the correction.
#biosky #chemsky /1
There really needs to be a conversation about right to repair for scientific instruments.
Configuration parameters hidden behind service codes.
Manufacturers refusing to sell components because they are “service only”
This all raises the cost of research.
#chemsky
Configuration parameters hidden behind service codes.
Manufacturers refusing to sell components because they are “service only”
This all raises the cost of research.
#chemsky
December 5, 2024 at 3:22 PM
There really needs to be a conversation about right to repair for scientific instruments.
Configuration parameters hidden behind service codes.
Manufacturers refusing to sell components because they are “service only”
This all raises the cost of research.
#chemsky
Configuration parameters hidden behind service codes.
Manufacturers refusing to sell components because they are “service only”
This all raises the cost of research.
#chemsky
Acquity Classic SM repair. Intermittent split peaks, inconsistent injection volumes, and failure to reproducibly calibrate sample loop volume traced back to a faulty vacuum pump. The pump is behind the Peltier chiller module, but mounting screws were under the power supply 🤷 #chemsky
December 3, 2024 at 6:10 PM
Acquity Classic SM repair. Intermittent split peaks, inconsistent injection volumes, and failure to reproducibly calibrate sample loop volume traced back to a faulty vacuum pump. The pump is behind the Peltier chiller module, but mounting screws were under the power supply 🤷 #chemsky
