#NeuroDegeneration preprints
@prepub-neurodegen.bsky.social
feeds: biorxiv, medrxiv, arxiv.q-bio, arxiv.cs, arxiv.math, Research Square
regex: "(neurodegeneration|Alzheimer|Parkinson's|Huntington|amyloid lateral sclerosis|multiple sclerosis|Apoe4)"
All contacts to @willmacnair :)
regex: "(neurodegeneration|Alzheimer|Parkinson's|Huntington|amyloid lateral sclerosis|multiple sclerosis|Apoe4)"
All contacts to @willmacnair :)
A Functional Resting-State Network Atlas Based on 420 Older Adults with Hypertension #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690831v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690831v1
December 2, 2025 at 8:01 AM
A Functional Resting-State Network Atlas Based on 420 Older Adults with Hypertension #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690831v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690831v1
GPR34 regulation of disease-associated microglial states and responses to physiological stimuli #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690816v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690816v1
December 2, 2025 at 8:01 AM
GPR34 regulation of disease-associated microglial states and responses to physiological stimuli #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690816v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690816v1
Intranigral injection of Alpha-Synuclein pre-formed fibrils leads to BBB compromise and Bilateral Dopaminergic Neurodegeneration in A53T Alpha-Synuclein transgenic mice. #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690780v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690780v1
December 2, 2025 at 8:01 AM
Intranigral injection of Alpha-Synuclein pre-formed fibrils leads to BBB compromise and Bilateral Dopaminergic Neurodegeneration in A53T Alpha-Synuclein transgenic mice. #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690780v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690780v1
Early, sex-dependent and progressive proteomic imbalance in the amygdala during Alzheimers disease progression #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690815v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690815v1
December 2, 2025 at 8:01 AM
Early, sex-dependent and progressive proteomic imbalance in the amygdala during Alzheimers disease progression #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690815v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690815v1
Proteomic Analysis in Alzheimer's Disease with Psychosis Reveals Separate Molecular Signatures for Core AD Proteinopathy and Postsynaptic Density Disruption #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690872v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690872v1
December 2, 2025 at 8:01 AM
Proteomic Analysis in Alzheimer's Disease with Psychosis Reveals Separate Molecular Signatures for Core AD Proteinopathy and Postsynaptic Density Disruption #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.26.690872v1
https://www.biorxiv.org/content/10.1101/2025.11.26.690872v1
Modeling Temporal Dependencies and Feature Interactions Reveal Novel Clinical and Molecular Insights into Alzheimer's Disease Progression #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.690894v1
https://www.biorxiv.org/content/10.1101/2025.11.27.690894v1
December 2, 2025 at 8:01 AM
Modeling Temporal Dependencies and Feature Interactions Reveal Novel Clinical and Molecular Insights into Alzheimer's Disease Progression #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.690894v1
https://www.biorxiv.org/content/10.1101/2025.11.27.690894v1
Amyloid-β 42-carrying extracellular vesicles are associated with neurodegeneration and neuroinflammation in Alzheimer's disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.690912v1
https://www.biorxiv.org/content/10.1101/2025.11.27.690912v1
December 2, 2025 at 8:01 AM
Amyloid-β 42-carrying extracellular vesicles are associated with neurodegeneration and neuroinflammation in Alzheimer's disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.690912v1
https://www.biorxiv.org/content/10.1101/2025.11.27.690912v1
Longitudinal Proteomic Profiling Defines Robust Molecular Subtypes Underlying the Heterogeneity of Parkinson's Disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.691036v1
https://www.biorxiv.org/content/10.1101/2025.11.27.691036v1
December 2, 2025 at 8:01 AM
Longitudinal Proteomic Profiling Defines Robust Molecular Subtypes Underlying the Heterogeneity of Parkinson's Disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.691036v1
https://www.biorxiv.org/content/10.1101/2025.11.27.691036v1
Reevaluating the Role of Beta2-Microglobulin: New Insights on Selective Vulnerability in ALS Pathology #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.690988v1
https://www.biorxiv.org/content/10.1101/2025.11.27.690988v1
December 2, 2025 at 8:01 AM
Reevaluating the Role of Beta2-Microglobulin: New Insights on Selective Vulnerability in ALS Pathology #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.690988v1
https://www.biorxiv.org/content/10.1101/2025.11.27.690988v1
Nuclear RNA Clusters Are Dynamic Structural Entities in Huntington's Disease. #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.691003v1
https://www.biorxiv.org/content/10.1101/2025.11.27.691003v1
December 2, 2025 at 8:01 AM
Nuclear RNA Clusters Are Dynamic Structural Entities in Huntington's Disease. #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.27.691003v1
https://www.biorxiv.org/content/10.1101/2025.11.27.691003v1
Protein Compositional Ratio Representation (PCRR)Systematically Improves Human Disease Prediction #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.29.691286v1
https://www.biorxiv.org/content/10.1101/2025.11.29.691286v1
December 2, 2025 at 8:01 AM
Protein Compositional Ratio Representation (PCRR)Systematically Improves Human Disease Prediction #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.29.691286v1
https://www.biorxiv.org/content/10.1101/2025.11.29.691286v1
Forecasting Alzheimer’s Disease Progression via Identity-preserved Denoising Diffusion Generative Adversarial Network #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7846693/latest
https://www.researchsquare.com/article/rs-7846693/latest
December 1, 2025 at 5:02 PM
Forecasting Alzheimer’s Disease Progression via Identity-preserved Denoising Diffusion Generative Adversarial Network #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7846693/latest
https://www.researchsquare.com/article/rs-7846693/latest
Impact of fasting status and storage time on plasma Amyloid-β 42 and 40, p-tau181, p-tau231, GFAP and NfL measurements #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8107685/latest
https://www.researchsquare.com/article/rs-8107685/latest
December 1, 2025 at 5:02 PM
Impact of fasting status and storage time on plasma Amyloid-β 42 and 40, p-tau181, p-tau231, GFAP and NfL measurements #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8107685/latest
https://www.researchsquare.com/article/rs-8107685/latest
Distributional genetic effects reveal context-dependent molecular regulation in human brain aging and Alzheimer’s disease #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8219833/latest
https://www.researchsquare.com/article/rs-8219833/latest
December 1, 2025 at 5:02 PM
Distributional genetic effects reveal context-dependent molecular regulation in human brain aging and Alzheimer’s disease #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8219833/latest
https://www.researchsquare.com/article/rs-8219833/latest
Dynamic Neurocognitive Adaptation: Childhood and Adult-Midlife Engagement Predict Later-Life Brain Structure and Cognition in Older Adults with and without Cognitive Impairment #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7971358/latest
https://www.researchsquare.com/article/rs-7971358/latest
December 1, 2025 at 5:02 PM
Dynamic Neurocognitive Adaptation: Childhood and Adult-Midlife Engagement Predict Later-Life Brain Structure and Cognition in Older Adults with and without Cognitive Impairment #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7971358/latest
https://www.researchsquare.com/article/rs-7971358/latest
Liver X Receptor activation protects Huntington’s disease knock-in mice from behavioral and neuropathological impairments #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8155849/latest
https://www.researchsquare.com/article/rs-8155849/latest
December 1, 2025 at 5:02 PM
Liver X Receptor activation protects Huntington’s disease knock-in mice from behavioral and neuropathological impairments #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8155849/latest
https://www.researchsquare.com/article/rs-8155849/latest
Electrocardiographic Indices Predicting Disability in Relapsing- Remitting Multiple Sclerosis: A Cross-Sectional Study #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7924456/latest
https://www.researchsquare.com/article/rs-7924456/latest
December 1, 2025 at 5:02 PM
Electrocardiographic Indices Predicting Disability in Relapsing- Remitting Multiple Sclerosis: A Cross-Sectional Study #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7924456/latest
https://www.researchsquare.com/article/rs-7924456/latest
Prognostic value of retinal neurodegeneration markers for the progression of diabetic retinopathy: a systematic review and meta-analysis #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8149687/latest
https://www.researchsquare.com/article/rs-8149687/latest
December 1, 2025 at 5:02 PM
Prognostic value of retinal neurodegeneration markers for the progression of diabetic retinopathy: a systematic review and meta-analysis #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8149687/latest
https://www.researchsquare.com/article/rs-8149687/latest
Microvascular pathology in the spinal cord of severe spinal muscular atrophy patients #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8085055/latest
https://www.researchsquare.com/article/rs-8085055/latest
December 1, 2025 at 5:02 PM
Microvascular pathology in the spinal cord of severe spinal muscular atrophy patients #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8085055/latest
https://www.researchsquare.com/article/rs-8085055/latest
Correlations of CSF Biomarkers of Alzheimer’s Disease with Cognitive Measures in MCI and AD Dementia: A Cross-Sectional Analysis #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8168314/latest
https://www.researchsquare.com/article/rs-8168314/latest
December 1, 2025 at 5:02 PM
Correlations of CSF Biomarkers of Alzheimer’s Disease with Cognitive Measures in MCI and AD Dementia: A Cross-Sectional Analysis #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8168314/latest
https://www.researchsquare.com/article/rs-8168314/latest
Duration of contact sports play associated with aberrant DNA methylation in human frontal cortex #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7861173/latest
https://www.researchsquare.com/article/rs-7861173/latest
December 1, 2025 at 5:02 PM
Duration of contact sports play associated with aberrant DNA methylation in human frontal cortex #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7861173/latest
https://www.researchsquare.com/article/rs-7861173/latest
AETA peptide drives Alzheimer’s disease signature of synapse dysfunction #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8192959/latest
https://www.researchsquare.com/article/rs-8192959/latest
December 1, 2025 at 5:02 PM
AETA peptide drives Alzheimer’s disease signature of synapse dysfunction #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8192959/latest
https://www.researchsquare.com/article/rs-8192959/latest
Inflammatory CADASIL: the cross-link between CADASIL and multiple sclerosis: a report of two cases and systematic review of literature #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8070069/latest
https://www.researchsquare.com/article/rs-8070069/latest
December 1, 2025 at 5:02 PM
Inflammatory CADASIL: the cross-link between CADASIL and multiple sclerosis: a report of two cases and systematic review of literature #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8070069/latest
https://www.researchsquare.com/article/rs-8070069/latest
Plasma pTau-181 Exhibits Flat Longitudinal Trajectories and Weak Cognitive Correlation in UK Biobank: Implications for Anti-Tau Antibody Trial Failures #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8204349/latest
https://www.researchsquare.com/article/rs-8204349/latest
December 1, 2025 at 5:02 PM
Plasma pTau-181 Exhibits Flat Longitudinal Trajectories and Weak Cognitive Correlation in UK Biobank: Implications for Anti-Tau Antibody Trial Failures #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8204349/latest
https://www.researchsquare.com/article/rs-8204349/latest
RNA interactions drive structural and functional diversification of alpha-synuclein fibrils #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.30.691421v1
https://www.biorxiv.org/content/10.1101/2025.11.30.691421v1
December 1, 2025 at 5:01 PM
RNA interactions drive structural and functional diversification of alpha-synuclein fibrils #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.30.691421v1
https://www.biorxiv.org/content/10.1101/2025.11.30.691421v1