Robust design:
✔️ Two independent radiologists read the scans blindly
✔️ High agreement between them
✔️ Consensus team validated all findings

We analysed 255 MS scans.
🔍 Compared two post-contrast sequences: Turbo Spin Echo (TSE) vs Turbo Field Echo (TFE).
📈 TSE showed almost twice as many enhancing lesions as TFE.

Early detection of active lesions can facilitate timely and effective treatments, potentially improving clinical outcomes for MS patients. 🕒💡(4/5)

This combination notably boosts agreement among radiologists, especially helpful for less experienced readers, ensuring consistency and reliability in lesion detection. (3/5)

🧵Excited to share our latest publication in Clinical Neuroradiology! 🚀🧠 We show that adding post-contrast susceptibility-weighted imaging (SWI+C) significantly enhances the detection of active lesions in multiple sclerosis (MS). (1/5)

Frontal Aslant Tract. Vertical associative fiber pre-supplementary motor area to IFG. Important role in language production and motor This patient for example had a met with edema englobing the tract and had trouble initiating speech. Resolved after anti-edema drugs and resection

Damage to the corticospinal tract can cause permanent motor damage! Especially damage to pre-central fibers.

Corticospinal tract. Most important projection fiber tract. Contains motor and sensory fibers from pre-motor, precentral (primary motor) and post-central cortices via the posterior limb of the internal capsule all the way to the spinal cord. Most fibers decussate in the medulla.

Cingulum. Part of the limbic system, surrounds the corpus callosum medial to other associative and projection fibers. At the level of the splenium an narrow extension of white-matter tract through the parahippocampal gyrus extends to the amygdala.

Uncinate fasciculus. Part of the indirect ventral stream and also part of the limbic system. Connects prefrontal regions to temporal pole via the temporal stem.

Inferior Longitudinal Fasciculus. Along with Uncinate fasciculus, it is part of the indirect ventral associative stream. Connects anterior temporal pole to occipital pole. Courses immediately infero-lateral to IFOF.

IFOF superficial (yellow) and deep (orange segments). Longest associative tract connects prefrontal areas to parietal (superficial segment) and occipital (deep segment) lobes via the infeiror external capsule and posterior temporal white-matter.

Ventral associative stream. WHAT pathway. Language role. Words -> meaning.
- Direct pathway: Inferior fronto-occipital fasciculus (IFOF)
- Indirect pathway:
- Uncinate (fronto-temporal)
- Inferior longitudinal fasciculus (ILF) (temporo-occipital)

RED: Long segment of arcuate: Inferior frontal gyrus (IFG) to posterior lateral temporal region
GREEN: Horizontal Short segment of arcuate: IFG to inferior parietal lobe.
YELLOW: Short vertical segment of arcuate: Inferior parietal lobe to posterior lateral temporal region.

Dorsal associative stream. WHERE pathway. Language role: Speech articulation and phonological processing.
Arcuate /superior longitudinal fasciculus composed of 3 segments.
- Long (fronto-temp) - classical arcuate
- Short horizontal (fronto-pariet)
- Short vertical (pariet-temp)

Brief anatomic-functional review of main white-matter tracts! Open Thread.
Covering corticospinal, ventral and dorsal associative streams, frontal aslant, and cingulum.
#neurorad #FOAMrad #neurosurg

Why is the "T1 DARK RIM" a big deal in #MultipleSclerosis #MRI?

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