Ilya Pletenev
@pletenev.bsky.social
PhD student at Skoltech, bioinformatician interested in 3D genomics
Excited to share our lab's latest preprint: www.biorxiv.org/content/10.1...
Using publicly available single-cell brain atlases of 3D chromatin interactions, we provide evidence that Polycomb contacts are involved in regulating transcription in neuronal subtypes by repressing "wrong" identity genes.
Using publicly available single-cell brain atlases of 3D chromatin interactions, we provide evidence that Polycomb contacts are involved in regulating transcription in neuronal subtypes by repressing "wrong" identity genes.
Ultra-long-range Polycomb-coupled interactions underlie subtype identity of human cortical neurons
Regulation of gene expression by Polycomb group (PcG) proteins orchestrates neural development and cell-type specification. However, the mechanisms by which neural progenitor cells diversify into the ...
www.biorxiv.org
November 7, 2025 at 6:09 AM
Excited to share our lab's latest preprint: www.biorxiv.org/content/10.1...
Using publicly available single-cell brain atlases of 3D chromatin interactions, we provide evidence that Polycomb contacts are involved in regulating transcription in neuronal subtypes by repressing "wrong" identity genes.
Using publicly available single-cell brain atlases of 3D chromatin interactions, we provide evidence that Polycomb contacts are involved in regulating transcription in neuronal subtypes by repressing "wrong" identity genes.