Phil Holliger
@philholliger.bsky.social
Program Leader and Head of PNAC division at MRC Laboratory of Molecular Biology, Cambridge, UK @mrclmb.bsky.social. Synthetic / Chemical biology and all things RNA
Reposted by Phil Holliger
Read this #preprint on @researchsquare: Base modifications reshape RNA folding landscapes and structure–function relationships in synthetic and natural RNAs
www.researchsquare.com/article/rs-6...
www.researchsquare.com/article/rs-6...
Base modifications reshape RNA folding landscapes and structure–function relationships in synthetic and natural RNAs
Modified bases such as 5-methylcytosine (5mC) and N1-methyl-pseudouridine (N1Ψ) are widely used to reduce the immunogenicity of and enhance the stability and translational efficiency of therapeutic RN...
www.researchsquare.com
May 29, 2025 at 10:58 PM
Read this #preprint on @researchsquare: Base modifications reshape RNA folding landscapes and structure–function relationships in synthetic and natural RNAs
www.researchsquare.com/article/rs-6...
www.researchsquare.com/article/rs-6...