Peibo Xu | 许培博
@peibo.bsky.social
PhD in Neuroscience,
Current postdoctoral trainee @creminslab.bsky.social
#learn #sleep #memory
"学而时习之"
https://scholar.google.com/citations?user=c0EboOoAAAAJ&hl=en
Current postdoctoral trainee @creminslab.bsky.social
#learn #sleep #memory
"学而时习之"
https://scholar.google.com/citations?user=c0EboOoAAAAJ&hl=en
Pinned
Peibo Xu | 许培博
@peibo.bsky.social
· Nov 19
Look what came! Chinese Simplified translation of 'The Scientist's Guide to Writing'. Thanks to translator Peibo Xu @peibo.bsky.social.
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
So honored to spend time transplating this wonder book from Dr. Heard @stephenbheard.bsky.social during the quarantine time back to 2022!
Check out our lab's @creminslab.bsky.social new work! new computational method for imaging-based chromatin tracing data!
Introducing FISHnet, a graph-theory-based method for sensitive and specific identification of chromatin domains from single-cell sequential Oligopaints data.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
FISHnet: detecting chromatin domains in single-cell sequential Oligopaints imaging data - Nature Methods
FISHnet is a graph-theory-based method for sensitive and specific identification of 3D genome features in sequential Oligopaints data.
www.nature.com
May 15, 2025 at 2:38 PM
Check out our lab's @creminslab.bsky.social new work! new computational method for imaging-based chromatin tracing data!
Reposted by Peibo Xu | 许培博
Have changes in science over the past 50 years reduced the chances of trainees experiencing the joy of discovery?
elifesciences.org/articles/80711 – Eve Marder
elifesciences.org/articles/80711 – Eve Marder
April 26, 2025 at 3:50 PM
Have changes in science over the past 50 years reduced the chances of trainees experiencing the joy of discovery?
elifesciences.org/articles/80711 – Eve Marder
elifesciences.org/articles/80711 – Eve Marder
Reposted by Peibo Xu | 许培博
Celebrating 10 years of our lab with a new preprint:
www.biorxiv.org/content/10.1...
How does enhancer location within a TAD control transcriptional bursts from a cognate promoter?
Experiments by Jana Tünnermann and modelling by Gregory Roth
www.biorxiv.org/content/10.1...
How does enhancer location within a TAD control transcriptional bursts from a cognate promoter?
Experiments by Jana Tünnermann and modelling by Gregory Roth
March 29, 2025 at 12:46 PM
Celebrating 10 years of our lab with a new preprint:
www.biorxiv.org/content/10.1...
How does enhancer location within a TAD control transcriptional bursts from a cognate promoter?
Experiments by Jana Tünnermann and modelling by Gregory Roth
www.biorxiv.org/content/10.1...
How does enhancer location within a TAD control transcriptional bursts from a cognate promoter?
Experiments by Jana Tünnermann and modelling by Gregory Roth
Big congrats to @dingliu.bsky.social ! Glad to see this beautiful work is finally out.
Nice story on fabulous new work from @dingliu.bsky.social in my lab, just out today!...
Two dueling sets of hypothalamic neurons—one that responds to isolation and one to reunion—help maintain a mouse's social homeostasis, a new study reveals.
By @avaskham.bsky.social
#neuroskyence
www.thetransmitter.org/social-behav...
By @avaskham.bsky.social
#neuroskyence
www.thetransmitter.org/social-behav...
February 26, 2025 at 5:33 PM
Big congrats to @dingliu.bsky.social ! Glad to see this beautiful work is finally out.
Reposted by Peibo Xu | 许培博
Check out our latest preprint, where we cross-compared the molecular landscapes of immature neurons in the hippocampus in different mammalian species👨🐵🐷🐭, revealing specialized features in humans. www.biorxiv.org/content/10.1...
Comparative molecular landscapes of immature neurons in the mammalian dentate gyrus across species reveal special features in humans
Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis contribute to plasticity, learning and memory, but their evolutionary changes across species and specialized features...
www.biorxiv.org
February 19, 2025 at 7:10 AM
Check out our latest preprint, where we cross-compared the molecular landscapes of immature neurons in the hippocampus in different mammalian species👨🐵🐷🐭, revealing specialized features in humans. www.biorxiv.org/content/10.1...
Reposted by Peibo Xu | 许培博
I have been talking to the media, Time, Fortune, NBC, etc., to explain how the onslaught on science and NIH will impact the health of all Americans. Everyone knows someone who has cancer, heart disease, or depression. Spread the word about how cutting science impacts all.
time.com/7216299/nih-...
time.com/7216299/nih-...
Experts Call NIH Budget Cuts an 'Apocalypse' for Science
The reductions target indirect costs that cover administrative and equipment costs.
time.com
February 15, 2025 at 9:28 PM
I have been talking to the media, Time, Fortune, NBC, etc., to explain how the onslaught on science and NIH will impact the health of all Americans. Everyone knows someone who has cancer, heart disease, or depression. Spread the word about how cutting science impacts all.
time.com/7216299/nih-...
time.com/7216299/nih-...
Reposted by Peibo Xu | 许培博
Out today in @naturegenet.bsky.social -- PERFF-seq! With @tsionabay.bsky.social , @ronanchaligne.bsky.social, Bob Stickels, Meril Takizawa, + Ansu Satpathy, we describe this new assay to study rare populations with programmable nucleic acid cytometry. 1/n
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing - Nature Genetics
Programmable Enrichment via RNA FlowFISH by sequencing (PERFF-seq) isolates rare cells based on RNA marker transcripts for single-cell RNA sequencing profiling of complex tissues, with applicability t...
www.nature.com
January 8, 2025 at 1:30 PM
Out today in @naturegenet.bsky.social -- PERFF-seq! With @tsionabay.bsky.social , @ronanchaligne.bsky.social, Bob Stickels, Meril Takizawa, + Ansu Satpathy, we describe this new assay to study rare populations with programmable nucleic acid cytometry. 1/n
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Peibo Xu | 许培博
Knowing how to give a good talk is a crucial skill to have, but it's mostly not formally taught very well. Here's my strategy for how to prepare for the presentation, actually present it, and then answer the questions.
December 29, 2024 at 4:45 AM
Knowing how to give a good talk is a crucial skill to have, but it's mostly not formally taught very well. Here's my strategy for how to prepare for the presentation, actually present it, and then answer the questions.
Reposted by Peibo Xu | 许培博
Delighted to highlight our new paper in
@natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...
@natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...
Synaptic basis of feature selectivity in hippocampal neurons - Nature
A temporally asymmetric synaptic plasticity kernel results from bidirectional modifications of synaptic weights around the induction of a place field.
www.nature.com
December 18, 2024 at 10:00 PM
Delighted to highlight our new paper in
@natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...
@natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...
Reposted by Peibo Xu | 许培博
Congratulations to PhD student Rohan Patel @rohaniopatel.bsky.social: Awarded a new NIH F31 fellowship for his work to computationally explore chromatin patterns and mechanisms of loop extrusion in sequential oligopaints imaging data. doi.org/10.1101/2024...
x.com/PatelRohanD/...
x.com/PatelRohanD/...
December 5, 2024 at 12:49 PM
Congratulations to PhD student Rohan Patel @rohaniopatel.bsky.social: Awarded a new NIH F31 fellowship for his work to computationally explore chromatin patterns and mechanisms of loop extrusion in sequential oligopaints imaging data. doi.org/10.1101/2024...
x.com/PatelRohanD/...
x.com/PatelRohanD/...
Reposted by Peibo Xu | 许培博
December 4, 2024 at 4:34 PM
Reposted by Peibo Xu | 许培博
When Jerry Seinfeld is refining a joke, he works very hard to figure out what is the actual core funny part, so he knows what he can strip away. Same with your idea: you have to figure out what is its essence, to know what is the simplest form of it to work on. -Michael Fischbach @mfgrp.bsky.social
November 26, 2024 at 6:45 PM
When Jerry Seinfeld is refining a joke, he works very hard to figure out what is the actual core funny part, so he knows what he can strip away. Same with your idea: you have to figure out what is its essence, to know what is the simplest form of it to work on. -Michael Fischbach @mfgrp.bsky.social
Reposted by Peibo Xu | 许培博
Congratulations Dr. Chandrashekar 💐
Using human neurons homozygously-engineered with familial AD mutations, Harshini found a role for miswired promoter-enhancer multi-loops in dysregulated excitatory and inhibitory gene expression programs
doi.org/10.1101/2024...
Using human neurons homozygously-engineered with familial AD mutations, Harshini found a role for miswired promoter-enhancer multi-loops in dysregulated excitatory and inhibitory gene expression programs
doi.org/10.1101/2024...
November 25, 2024 at 11:05 AM
Congratulations Dr. Chandrashekar 💐
Using human neurons homozygously-engineered with familial AD mutations, Harshini found a role for miswired promoter-enhancer multi-loops in dysregulated excitatory and inhibitory gene expression programs
doi.org/10.1101/2024...
Using human neurons homozygously-engineered with familial AD mutations, Harshini found a role for miswired promoter-enhancer multi-loops in dysregulated excitatory and inhibitory gene expression programs
doi.org/10.1101/2024...
Reposted by Peibo Xu | 许培博
It's my great pleasure to present the next big preprint from SheqLab! An exciting application of our O-MAP platform that I hope will transform the study of nuclear architecture.
If you've ever wanted to dissect the subnuclear "neighborhood" around an individual locus, read on! (1/30)
If you've ever wanted to dissect the subnuclear "neighborhood" around an individual locus, read on! (1/30)
November 21, 2024 at 1:27 AM
It's my great pleasure to present the next big preprint from SheqLab! An exciting application of our O-MAP platform that I hope will transform the study of nuclear architecture.
If you've ever wanted to dissect the subnuclear "neighborhood" around an individual locus, read on! (1/30)
If you've ever wanted to dissect the subnuclear "neighborhood" around an individual locus, read on! (1/30)
Reposted by Peibo Xu | 许培博
In every project you end up getting to the "point of creative frustration", which leaves you with 3 options
November 20, 2024 at 12:12 AM
In every project you end up getting to the "point of creative frustration", which leaves you with 3 options
Reposted by Peibo Xu | 许培博
What separates the best research scientists from the rest, asks Keith Yamamoto (UCSF). There is no secret. The best scientists are simply reaching for the big discoveries. This means taking risks, which is really what's behind the joy of discovery.
www.youtube.com/watch?v=3-aH...
www.youtube.com/watch?v=3-aH...
Keith Yamamoto (UCSF): Taking Risks
YouTube video by iBiology Career and Professional Development
www.youtube.com
November 20, 2024 at 12:19 AM
What separates the best research scientists from the rest, asks Keith Yamamoto (UCSF). There is no secret. The best scientists are simply reaching for the big discoveries. This means taking risks, which is really what's behind the joy of discovery.
www.youtube.com/watch?v=3-aH...
www.youtube.com/watch?v=3-aH...
So honored to spend time transplating this wonder book from Dr. Heard @stephenbheard.bsky.social during the quarantine time back to 2022!
Look what came! Chinese Simplified translation of 'The Scientist's Guide to Writing'. Thanks to translator Peibo Xu @peibo.bsky.social.
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
November 19, 2024 at 2:48 PM
So honored to spend time transplating this wonder book from Dr. Heard @stephenbheard.bsky.social during the quarantine time back to 2022!
Reposted by Peibo Xu | 许培博
Look what came! Chinese Simplified translation of 'The Scientist's Guide to Writing'. Thanks to translator Peibo Xu @peibo.bsky.social.
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
November 19, 2024 at 2:40 PM
Look what came! Chinese Simplified translation of 'The Scientist's Guide to Writing'. Thanks to translator Peibo Xu @peibo.bsky.social.
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
I can add this to my growing shelf of translations of my books that I cannot understand 🙂🧪
Reposted by Peibo Xu | 许培博
There are many nuances regarding the structural neural plasticity associated with antidepressant drugs. 💊🧠
We share our thoughts here in a Nature Reviews Neuroscience article, led by Clara Liao with co-authors from Conor Liston’s lab at Weill Cornell.
www.nature.com/articles/s41...
We share our thoughts here in a Nature Reviews Neuroscience article, led by Clara Liao with co-authors from Conor Liston’s lab at Weill Cornell.
www.nature.com/articles/s41...
November 19, 2024 at 1:23 PM
There are many nuances regarding the structural neural plasticity associated with antidepressant drugs. 💊🧠
We share our thoughts here in a Nature Reviews Neuroscience article, led by Clara Liao with co-authors from Conor Liston’s lab at Weill Cornell.
www.nature.com/articles/s41...
We share our thoughts here in a Nature Reviews Neuroscience article, led by Clara Liao with co-authors from Conor Liston’s lab at Weill Cornell.
www.nature.com/articles/s41...
Reposted by Peibo Xu | 许培博
The New York Times reported on the rapid growth of @bsky.app. Today I also learned that Jay Graber, the CEO of Bluesky, is half Chinese, and her Chinese first name, Lantian (蓝天), literally means "blue sky."
www.nytimes.com/2024/11/17/t...
www.nytimes.com/2024/11/17/t...
How Bluesky, Alternative to X and Facebook, Is Handling Growth
The fledgling social media site has been flooded with new users since the election. It hasn’t all been easy.
www.nytimes.com
November 17, 2024 at 11:55 PM
The New York Times reported on the rapid growth of @bsky.app. Today I also learned that Jay Graber, the CEO of Bluesky, is half Chinese, and her Chinese first name, Lantian (蓝天), literally means "blue sky."
www.nytimes.com/2024/11/17/t...
www.nytimes.com/2024/11/17/t...
Reposted by Peibo Xu | 许培博
Download our database of 313 different postdoctoral fellowships.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
November 16, 2024 at 7:05 PM
Download our database of 313 different postdoctoral fellowships.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
Reposted by Peibo Xu | 许培博
Here are some free/open-source sites for the preparation of scientific illustrations, including icon libraries: bioicons.com, scidraw.io, bioart.niaid.nih.gov, inkscape.org, biogdp.com, reactome.org/icon-lib
November 17, 2024 at 4:04 PM
Here are some free/open-source sites for the preparation of scientific illustrations, including icon libraries: bioicons.com, scidraw.io, bioart.niaid.nih.gov, inkscape.org, biogdp.com, reactome.org/icon-lib