Peter Andolfatto
@pandolfatto.bsky.social
Evolution/Ecology meets Genetics @ Columbia University. We use a variety of organisms (🪰🦋🐸🪲) and approaches (mol evo and pop gen, mol bio, experimental evo, genetic engineering) to better understand constraints on adaptation.
Reposted by Peter Andolfatto
Join your local protest on April 19th. Spread the word.
April 14, 2025 at 12:58 AM
Join your local protest on April 19th. Spread the word.
Reposted by Peter Andolfatto
NYC, it’s time to take to the streets again.
We’re joining over 40 cosponsors to protest authoritarianism, and march for a planet where we place people over profit.
📅 Saturday, April 19
⏰ 12pm
📍 Bryant Park
We’ll see you in the streets.
We’re joining over 40 cosponsors to protest authoritarianism, and march for a planet where we place people over profit.
📅 Saturday, April 19
⏰ 12pm
📍 Bryant Park
We’ll see you in the streets.
April 13, 2025 at 11:00 PM
NYC, it’s time to take to the streets again.
We’re joining over 40 cosponsors to protest authoritarianism, and march for a planet where we place people over profit.
📅 Saturday, April 19
⏰ 12pm
📍 Bryant Park
We’ll see you in the streets.
We’re joining over 40 cosponsors to protest authoritarianism, and march for a planet where we place people over profit.
📅 Saturday, April 19
⏰ 12pm
📍 Bryant Park
We’ll see you in the streets.
Reposted by Peter Andolfatto
1. For the past thirty years I've had the best job in the world.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
March 19, 2025 at 7:32 PM
1. For the past thirty years I've had the best job in the world.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
Reposted by Peter Andolfatto
📢 Institut Jacques Monod Seminar
📅 February 14th
📍 Institut Jacques Monod
Next Friday, @pandolfatto.bsky.social , will give the IJM Seminar "The evolution of toxin-resistant Na+,K+-ATPases: new insights from frogs and fireflies"
➡️ https://buff.ly/40wHF1R
📅 February 14th
📍 Institut Jacques Monod
Next Friday, @pandolfatto.bsky.social , will give the IJM Seminar "The evolution of toxin-resistant Na+,K+-ATPases: new insights from frogs and fireflies"
➡️ https://buff.ly/40wHF1R
February 10, 2025 at 9:00 AM
📢 Institut Jacques Monod Seminar
📅 February 14th
📍 Institut Jacques Monod
Next Friday, @pandolfatto.bsky.social , will give the IJM Seminar "The evolution of toxin-resistant Na+,K+-ATPases: new insights from frogs and fireflies"
➡️ https://buff.ly/40wHF1R
📅 February 14th
📍 Institut Jacques Monod
Next Friday, @pandolfatto.bsky.social , will give the IJM Seminar "The evolution of toxin-resistant Na+,K+-ATPases: new insights from frogs and fireflies"
➡️ https://buff.ly/40wHF1R
Reposted by Peter Andolfatto
“The distribution of highly deleterious variants across human ancestry groups”. Preprint with Anastasia Stolyarova and @gcbias.bsky.social: www.biorxiv.org/content/10.1...
The distribution of highly deleterious variants across human ancestry groups
A major focus of human genetics is to map severe disease mutations. Increasingly that goal is understood as requiring huge numbers of people to be sequenced from every broadly-defined genetic ancestry...
www.biorxiv.org
February 2, 2025 at 7:00 PM
“The distribution of highly deleterious variants across human ancestry groups”. Preprint with Anastasia Stolyarova and @gcbias.bsky.social: www.biorxiv.org/content/10.1...
Reposted by Peter Andolfatto
Although it feels bizarre to be posting about research with what has been going on in the US this week, I want to highlight new work from graduate student @nemovrobles.bsky.social whose first-first author paper on mitonuclear incompatibilities in swordtails just posted on bioRxiv. shorturl.at/gC71V
Admixture mapping reveals evidence for multiple mitonuclear incompatibilities in swordtail fish hybrids
How barriers to gene flow arise between closely related species is one of the oldest questions in evolutionary biology. Classic models in evolutionary biology predict that negative epistatic interacti...
shorturl.at
February 1, 2025 at 11:17 PM
Although it feels bizarre to be posting about research with what has been going on in the US this week, I want to highlight new work from graduate student @nemovrobles.bsky.social whose first-first author paper on mitonuclear incompatibilities in swordtails just posted on bioRxiv. shorturl.at/gC71V
Reposted by Peter Andolfatto
"We describe a #mtDNA variant that confers protection against variety of pathogens in #Drosophila. This protection was at least partially caused by enhanced cell-mediated innate #immunity, including higher numbers of immune cells prior to and during infection."
journals.plos.org/plosgenetics...
journals.plos.org/plosgenetics...
A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila
Author summary The strength of immune response and the disease symptoms vary among individuals even when exposed to the same pathogen. Much of this variation is due to the genes directly involved in a...
journals.plos.org
December 11, 2024 at 8:10 PM
"We describe a #mtDNA variant that confers protection against variety of pathogens in #Drosophila. This protection was at least partially caused by enhanced cell-mediated innate #immunity, including higher numbers of immune cells prior to and during infection."
journals.plos.org/plosgenetics...
journals.plos.org/plosgenetics...
Reposted by Peter Andolfatto
This year I always had my camera and a small photo box to hand when I was gardening. My children are always finding caterpillars outside, and I wanted to document that a bit this year. With the exception of the garden tiger moth (Arctia caja), they all came from my garden.
December 9, 2024 at 8:21 PM
This year I always had my camera and a small photo box to hand when I was gardening. My children are always finding caterpillars outside, and I wanted to document that a bit this year. With the exception of the garden tiger moth (Arctia caja), they all came from my garden.
Reposted by Peter Andolfatto
Want to perform HIGH EFFICIENCY Homology Directed Repair in Drosophila spp? Try Atalanta plasmids. About 10X higher efficiency than other methods!
Tag or delete genes, invert chromosome regions, make scarless site-specific modifications. All with easy cloning.
This paper is proudly bioRxiv only!
Tag or delete genes, invert chromosome regions, make scarless site-specific modifications. All with easy cloning.
This paper is proudly bioRxiv only!
December 7, 2024 at 1:10 AM
Want to perform HIGH EFFICIENCY Homology Directed Repair in Drosophila spp? Try Atalanta plasmids. About 10X higher efficiency than other methods!
Tag or delete genes, invert chromosome regions, make scarless site-specific modifications. All with easy cloning.
This paper is proudly bioRxiv only!
Tag or delete genes, invert chromosome regions, make scarless site-specific modifications. All with easy cloning.
This paper is proudly bioRxiv only!
Reposted by Peter Andolfatto
📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you.
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
November 25, 2024 at 11:19 AM
📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you.
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
Reposted by Peter Andolfatto
Just posting this to #popgen
Here's a link to my notes on population & quantitative genetics:
github.com/cooplab/popg...
Hoping to extend it more after the winter holidays, as I'm just finishing up teaching the undergrad version of class.
Here's a link to my notes on population & quantitative genetics:
github.com/cooplab/popg...
Hoping to extend it more after the winter holidays, as I'm just finishing up teaching the undergrad version of class.
Releases · cooplab/popgen-notes
Population genetics notes. Contribute to cooplab/popgen-notes development by creating an account on GitHub.
github.com
November 19, 2024 at 11:37 PM
Just posting this to #popgen
Here's a link to my notes on population & quantitative genetics:
github.com/cooplab/popg...
Hoping to extend it more after the winter holidays, as I'm just finishing up teaching the undergrad version of class.
Here's a link to my notes on population & quantitative genetics:
github.com/cooplab/popg...
Hoping to extend it more after the winter holidays, as I'm just finishing up teaching the undergrad version of class.
Reposted by Peter Andolfatto
Please share widely: The 2025 Speciation Gordon Research Conference (March 2-7 2025) is now open for registration to anyone. If you wish to attend, apply here:
www.grc.org/speciation-c...
Attendees can present posters, and there are a couple open talk slots to be filled from poster abstracts.
www.grc.org/speciation-c...
Attendees can present posters, and there are a couple open talk slots to be filled from poster abstracts.
2025 Speciation Conference GRC
The 2025 Gordon Research Conference on Speciation will be held in Ventura, California. Apply today to reserve your spot.
www.grc.org
September 3, 2024 at 1:58 PM
Please share widely: The 2025 Speciation Gordon Research Conference (March 2-7 2025) is now open for registration to anyone. If you wish to attend, apply here:
www.grc.org/speciation-c...
Attendees can present posters, and there are a couple open talk slots to be filled from poster abstracts.
www.grc.org/speciation-c...
Attendees can present posters, and there are a couple open talk slots to be filled from poster abstracts.
Reposted by Peter Andolfatto
A really nice News and Views about our paper by @tollkuhn.bsky.social 🙏🏽
www.nature.com/articles/d41...
www.nature.com/articles/d41...
May 15, 2024 at 6:30 PM
A really nice News and Views about our paper by @tollkuhn.bsky.social 🙏🏽
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Peter Andolfatto
How do animals know when it’s their turn to communicate during a conversation?
In our latest preprint, we study the behavior and neurobiology of aggressive visual turn-taking of Siamese fighting (betta) fish to find out.
Work lead by Claire Everett
🧵 1/8
www.biorxiv.org/content/10.1...
In our latest preprint, we study the behavior and neurobiology of aggressive visual turn-taking of Siamese fighting (betta) fish to find out.
Work lead by Claire Everett
🧵 1/8
www.biorxiv.org/content/10.1...
May 2, 2024 at 8:33 PM
How do animals know when it’s their turn to communicate during a conversation?
In our latest preprint, we study the behavior and neurobiology of aggressive visual turn-taking of Siamese fighting (betta) fish to find out.
Work lead by Claire Everett
🧵 1/8
www.biorxiv.org/content/10.1...
In our latest preprint, we study the behavior and neurobiology of aggressive visual turn-taking of Siamese fighting (betta) fish to find out.
Work lead by Claire Everett
🧵 1/8
www.biorxiv.org/content/10.1...
Reposted by Peter Andolfatto
Nice write up in Science Magazine about our ivory lncRNA color patterning preprints! Way to go @hwkmthcrspr.bsky.social, @lucalivraghi.bsky.social, and Tian Shen!
www.science.org/content/arti...
www.science.org/content/arti...
Surprise RNAs solve mystery of how butterfly wings get their colorful patterns
Understudied means of regulating genes likely widespread in butterflies—and perhaps other animals
www.science.org
February 29, 2024 at 11:18 PM
Nice write up in Science Magazine about our ivory lncRNA color patterning preprints! Way to go @hwkmthcrspr.bsky.social, @lucalivraghi.bsky.social, and Tian Shen!
www.science.org/content/arti...
www.science.org/content/arti...
Reposted by Peter Andolfatto
Excited to share a new pre-print from our lab that demonstrates surprisingly repeatable genome evolution in replicated Xiphophorus hybrid populations! Led by former postdoc Quinn Langdon with substantial contributions from Jeff Groh from @gcbias.bsky.social's lab: www.biorxiv.org/content/10.1...
December 23, 2023 at 11:23 PM
Excited to share a new pre-print from our lab that demonstrates surprisingly repeatable genome evolution in replicated Xiphophorus hybrid populations! Led by former postdoc Quinn Langdon with substantial contributions from Jeff Groh from @gcbias.bsky.social's lab: www.biorxiv.org/content/10.1...
Reposted by Peter Andolfatto
Zach Baker's paper modeling the rapid evolution of PRDM9 is now out in eLife: elifesciences.org/articles/83769
December 14, 2023 at 11:48 PM
Zach Baker's paper modeling the rapid evolution of PRDM9 is now out in eLife: elifesciences.org/articles/83769
Reposted by Peter Andolfatto
This is me trying out Blusky! I am interested in #viruses #genomes #Drosophila #evolution and #popgen.
Here is a pretty picture of some flies from the UK, as an attention-grabber (visit obbard.bio.ed.ac.uk/photos.html for more!)
Here is a pretty picture of some flies from the UK, as an attention-grabber (visit obbard.bio.ed.ac.uk/photos.html for more!)
December 5, 2023 at 5:58 PM
This is me trying out Blusky! I am interested in #viruses #genomes #Drosophila #evolution and #popgen.
Here is a pretty picture of some flies from the UK, as an attention-grabber (visit obbard.bio.ed.ac.uk/photos.html for more!)
Here is a pretty picture of some flies from the UK, as an attention-grabber (visit obbard.bio.ed.ac.uk/photos.html for more!)