Nikos Karaiskos
@nukappa.bsky.social
Spatial Transcriptomics • Bioinformatics • Comp Biology
Research Scientist @mdc-berlin.bsky.social
Research Scientist @mdc-berlin.bsky.social
Reposted by Nikos Karaiskos
We’re happy to share our new preprint form
@N_Rajewsky, with @tmpentimalli.bsky.social i.bsky.social @Ilan Theurillat
lab! 🎉
🧬 Spatiotemporal atlas of tumor–stroma crosstalk in a new TNBC model. Spatial transcriptomics (Open-ST), snRNA-seq, and functional validation.
🔗 biorxiv.org/content/10.1...
@N_Rajewsky, with @tmpentimalli.bsky.social i.bsky.social @Ilan Theurillat
lab! 🎉
🧬 Spatiotemporal atlas of tumor–stroma crosstalk in a new TNBC model. Spatial transcriptomics (Open-ST), snRNA-seq, and functional validation.
🔗 biorxiv.org/content/10.1...
Spatiotemporal dynamics of tumor microenvironment remodeling
During tumorigenesis, interactions between tumor and stromal cells progressively remodel the tumor microenvironment (TME) towards pro-tumoral functions. Understanding early TME remodeling dynamics is ...
biorxiv.org
July 22, 2025 at 9:48 AM
We’re happy to share our new preprint form
@N_Rajewsky, with @tmpentimalli.bsky.social i.bsky.social @Ilan Theurillat
lab! 🎉
🧬 Spatiotemporal atlas of tumor–stroma crosstalk in a new TNBC model. Spatial transcriptomics (Open-ST), snRNA-seq, and functional validation.
🔗 biorxiv.org/content/10.1...
@N_Rajewsky, with @tmpentimalli.bsky.social i.bsky.social @Ilan Theurillat
lab! 🎉
🧬 Spatiotemporal atlas of tumor–stroma crosstalk in a new TNBC model. Spatial transcriptomics (Open-ST), snRNA-seq, and functional validation.
🔗 biorxiv.org/content/10.1...
Reposted by Nikos Karaiskos
Our 3D study of the tumor microenvironment is finally out!
Play around with the data yourself at lung-3d-browser.mdc-berlin.de (Kudos to @danilexn.bsky.social👏 )
Many thanks to Nikolaus Rajewsky lab at @mdc-bimsb.bsky.social and everyone involved, it takes a village to raise a multimodal paper!
Play around with the data yourself at lung-3d-browser.mdc-berlin.de (Kudos to @danilexn.bsky.social👏 )
Many thanks to Nikolaus Rajewsky lab at @mdc-bimsb.bsky.social and everyone involved, it takes a village to raise a multimodal paper!
April 16, 2025 at 10:40 AM
Our 3D study of the tumor microenvironment is finally out!
Play around with the data yourself at lung-3d-browser.mdc-berlin.de (Kudos to @danilexn.bsky.social👏 )
Many thanks to Nikolaus Rajewsky lab at @mdc-bimsb.bsky.social and everyone involved, it takes a village to raise a multimodal paper!
Play around with the data yourself at lung-3d-browser.mdc-berlin.de (Kudos to @danilexn.bsky.social👏 )
Many thanks to Nikolaus Rajewsky lab at @mdc-bimsb.bsky.social and everyone involved, it takes a village to raise a multimodal paper!
Reposted by Nikos Karaiskos
🧬 Want to implement Open-ST in your lab?
We've published a detailed guide that takes you from tissue sections to 3D molecular maps
star-protocols.cell.com/protocols/3922
We've published a detailed guide that takes you from tissue sections to 3D molecular maps
star-protocols.cell.com/protocols/3922
January 10, 2025 at 12:38 PM
🧬 Want to implement Open-ST in your lab?
We've published a detailed guide that takes you from tissue sections to 3D molecular maps
star-protocols.cell.com/protocols/3922
We've published a detailed guide that takes you from tissue sections to 3D molecular maps
star-protocols.cell.com/protocols/3922
#SpatialTranscriptomics is revolutionizing gene expression profiling at subcellular resolution!
🔬These 'molecular microscopes' can unlock disease mechanisms & guide therapies... But how to bring ST to the clinic?
Our thoughts with T. Pentimalli and N. Rajewsky out @annualreviews.bsky.social 🧵👇
🔬These 'molecular microscopes' can unlock disease mechanisms & guide therapies... But how to bring ST to the clinic?
Our thoughts with T. Pentimalli and N. Rajewsky out @annualreviews.bsky.social 🧵👇
December 18, 2024 at 2:36 PM
#SpatialTranscriptomics is revolutionizing gene expression profiling at subcellular resolution!
🔬These 'molecular microscopes' can unlock disease mechanisms & guide therapies... But how to bring ST to the clinic?
Our thoughts with T. Pentimalli and N. Rajewsky out @annualreviews.bsky.social 🧵👇
🔬These 'molecular microscopes' can unlock disease mechanisms & guide therapies... But how to bring ST to the clinic?
Our thoughts with T. Pentimalli and N. Rajewsky out @annualreviews.bsky.social 🧵👇