Niels Keijzer
@nkeijzer.bsky.social
PhD student at the Netherlands Cancer Institute | Biochemistry & Structural Biology
I figured the previous mysterious image deserved an upgrade!
USP1/UAF1's exo-cleavage mechanism, and its preference for polyubiquitinated PCNA, may drive DNA damage tolerance pathway choice by enriching for monoubiquitinated PCNA.
Read our preprint for our full analysis:
doi.org/10.1101/2024...
USP1/UAF1's exo-cleavage mechanism, and its preference for polyubiquitinated PCNA, may drive DNA damage tolerance pathway choice by enriching for monoubiquitinated PCNA.
Read our preprint for our full analysis:
doi.org/10.1101/2024...
December 20, 2024 at 1:55 PM
I figured the previous mysterious image deserved an upgrade!
USP1/UAF1's exo-cleavage mechanism, and its preference for polyubiquitinated PCNA, may drive DNA damage tolerance pathway choice by enriching for monoubiquitinated PCNA.
Read our preprint for our full analysis:
doi.org/10.1101/2024...
USP1/UAF1's exo-cleavage mechanism, and its preference for polyubiquitinated PCNA, may drive DNA damage tolerance pathway choice by enriching for monoubiquitinated PCNA.
Read our preprint for our full analysis:
doi.org/10.1101/2024...