see this guy regularly here in San Diego

Still frame of the Osprey

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CTI-111 binds multiple sepsis-associated human cytokines in the complex environment of ex vivo septic serum—highlighting its potential as a multifaceted sepsis therapy

Ongoing work is expanding CTI-111's utility to additional severe infectious or inflammatory conditions

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Article @ ACS Nano:

Human macrophage membrane-derived drug candidate CTI-111 sequesters soluble microbial toxins, drivers of inflammation, and pro-inflammatory cytokines from multiple sources. Therapeutic administration of CTI-111 reduces inflammation and improves survival in multiple murine sepsis models

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In the United States, sepsis results in the hospitalization of more than one million patients annually and accounts for nearly one in three hospital deaths. Despite decades of efforts to develop immunoregulatory sepsis therapies, no clinically approved treatments exist.

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