ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
@nizet.bsky.social
Physician-scientist at UC San Diego, Microbiology, Immunology, Novel Drug and Vaccine Discovery, #IDSky, Mentoring and Supporting STEM Career Development.
Enjoy exploring the outdoors, world cultures, sports, comedy, community.
http://nizetlab.ucsd.edu
Enjoy exploring the outdoors, world cultures, sports, comedy, community.
http://nizetlab.ucsd.edu
see this guy regularly here in San Diego
December 1, 2025 at 12:35 AM
see this guy regularly here in San Diego
November 28, 2025 at 2:53 PM
Still frame of the Osprey
November 27, 2025 at 6:37 PM
Still frame of the Osprey
Some real "Mutual of Omaha's Wild Kingdom" action this Thanksgiving morning on a light pole one block from my house — a magnificent Osprey with his half-eaten fish and a crow that thinks he should share — watch the video with the sound on to hear them haggle it out
November 27, 2025 at 6:36 PM
Some real "Mutual of Omaha's Wild Kingdom" action this Thanksgiving morning on a light pole one block from my house — a magnificent Osprey with his half-eaten fish and a crow that thinks he should share — watch the video with the sound on to hear them haggle it out
though not as common as
Graham-negative crackers,
Graham-positive ones are the
most tasty
Graham-negative crackers,
Graham-positive ones are the
most tasty
November 26, 2025 at 12:21 PM
though not as common as
Graham-negative crackers,
Graham-positive ones are the
most tasty
Graham-negative crackers,
Graham-positive ones are the
most tasty
hyaluronic acid has been a significant player in the cosmetic market in recent years — so now it seems sialic acid is giving it a shot #glycotime
November 25, 2025 at 6:29 PM
hyaluronic acid has been a significant player in the cosmetic market in recent years — so now it seems sialic acid is giving it a shot #glycotime
Zengler Lab @UCSan Diego
coralME, a next-gen tool that rapidly builds genome-scale models for 495 gut microbes—models revealing what each microbe eats, what it produces, and how diet and disease reshape microbiome chemistry—clear mechanistic window into biology of IBD
www.cell.com/action/showP...
coralME, a next-gen tool that rapidly builds genome-scale models for 495 gut microbes—models revealing what each microbe eats, what it produces, and how diet and disease reshape microbiome chemistry—clear mechanistic window into biology of IBD
www.cell.com/action/showP...
November 24, 2025 at 11:55 AM
Zengler Lab @UCSan Diego
coralME, a next-gen tool that rapidly builds genome-scale models for 495 gut microbes—models revealing what each microbe eats, what it produces, and how diet and disease reshape microbiome chemistry—clear mechanistic window into biology of IBD
www.cell.com/action/showP...
coralME, a next-gen tool that rapidly builds genome-scale models for 495 gut microbes—models revealing what each microbe eats, what it produces, and how diet and disease reshape microbiome chemistry—clear mechanistic window into biology of IBD
www.cell.com/action/showP...
A REAL PHAGE TURNER
Great work in Nat Comm from the UC San Diego laboratories of David Pride and Justin Meyer—experimental evolution of bacteriophage to successfully expand their host range against MDR strains of the critical threat pathogen Klebsiella pneumoniae.
www.nature.com/articles/s41...
Great work in Nat Comm from the UC San Diego laboratories of David Pride and Justin Meyer—experimental evolution of bacteriophage to successfully expand their host range against MDR strains of the critical threat pathogen Klebsiella pneumoniae.
www.nature.com/articles/s41...
November 22, 2025 at 10:05 PM
A REAL PHAGE TURNER
Great work in Nat Comm from the UC San Diego laboratories of David Pride and Justin Meyer—experimental evolution of bacteriophage to successfully expand their host range against MDR strains of the critical threat pathogen Klebsiella pneumoniae.
www.nature.com/articles/s41...
Great work in Nat Comm from the UC San Diego laboratories of David Pride and Justin Meyer—experimental evolution of bacteriophage to successfully expand their host range against MDR strains of the critical threat pathogen Klebsiella pneumoniae.
www.nature.com/articles/s41...
Wonderful celebration of the illustrious UCSD career of beloved scientist and mentor 𝐏𝐀𝐋𝐌𝐄𝐑 𝐓𝐀𝐘𝐋𝐎𝐑, 𝐏𝐡𝐃—former Chair of Pharmacology and Founding & Emeritus Dean of our Skaggs School of Pharmacy—two day symposium of trainees and collaborators culminating with paella + acetylcholine cake chez Taylor!
November 19, 2025 at 12:10 AM
Wonderful celebration of the illustrious UCSD career of beloved scientist and mentor 𝐏𝐀𝐋𝐌𝐄𝐑 𝐓𝐀𝐘𝐋𝐎𝐑, 𝐏𝐡𝐃—former Chair of Pharmacology and Founding & Emeritus Dean of our Skaggs School of Pharmacy—two day symposium of trainees and collaborators culminating with paella + acetylcholine cake chez Taylor!
Lionfish at the Birch Aquarium of our Scripps Institution of Oceanography, here at the University of California, San Diego. Very beautiful and very venomous.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
November 15, 2025 at 10:29 PM
Lionfish at the Birch Aquarium of our Scripps Institution of Oceanography, here at the University of California, San Diego. Very beautiful and very venomous.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
Important update below on the eligibility criteria for the current round of funding from CARB-X, the hugely impactful accelerator for novel therapeutics, preventatives, and diagnostics to confront the AMR crisis. CARB-X can provide not only funding, but deep expertise to help companies succeed.
November 13, 2025 at 6:27 PM
Important update below on the eligibility criteria for the current round of funding from CARB-X, the hugely impactful accelerator for novel therapeutics, preventatives, and diagnostics to confront the AMR crisis. CARB-X can provide not only funding, but deep expertise to help companies succeed.
Most wildlife crimes vs gulls committed by men
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
November 13, 2025 at 4:47 PM
Most wildlife crimes vs gulls committed by men
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
Human macrophage membrane-derived drug candidate CTI-111 sequesters soluble microbial toxins, drivers of inflammation, and pro-inflammatory cytokines from multiple sources. Therapeutic administration of CTI-111 reduces inflammation and improves survival in multiple murine sepsis models
🧵 3/4
🧵 3/4
November 11, 2025 at 11:25 PM
Human macrophage membrane-derived drug candidate CTI-111 sequesters soluble microbial toxins, drivers of inflammation, and pro-inflammatory cytokines from multiple sources. Therapeutic administration of CTI-111 reduces inflammation and improves survival in multiple murine sepsis models
🧵 3/4
🧵 3/4
In the United States, sepsis results in the hospitalization of more than one million patients annually and accounts for nearly one in three hospital deaths. Despite decades of efforts to develop immunoregulatory sepsis therapies, no clinically approved treatments exist.
🧵2/4
🧵2/4
November 11, 2025 at 11:25 PM
In the United States, sepsis results in the hospitalization of more than one million patients annually and accounts for nearly one in three hospital deaths. Despite decades of efforts to develop immunoregulatory sepsis therapies, no clinically approved treatments exist.
🧵2/4
🧵2/4
Pleased to share our new work, spearheaded by Drs. Alex Hoffman and Elisabet Bjånes—in collaboration with the Liangfang Zhang Lab, Cellics Therapeutics, and CARB-X—debuting CTI-111, a biomimetic macrophage membrane-coated nanoparticle and candidate broad-spectrum adjunctive therapy for sepsis
🧵 1/4
🧵 1/4
November 11, 2025 at 11:25 PM
Pleased to share our new work, spearheaded by Drs. Alex Hoffman and Elisabet Bjånes—in collaboration with the Liangfang Zhang Lab, Cellics Therapeutics, and CARB-X—debuting CTI-111, a biomimetic macrophage membrane-coated nanoparticle and candidate broad-spectrum adjunctive therapy for sepsis
🧵 1/4
🧵 1/4
A visit to the University of Lausanne (UNIL) allowed me to drop in on my close colleague and former sabbatical professor Jan-Willem Veening's lab in the Department of Fundamental Microbiology, Biophore Building.
The view is not too bad!
The view is not too bad!
November 10, 2025 at 7:33 PM
A visit to the University of Lausanne (UNIL) allowed me to drop in on my close colleague and former sabbatical professor Jan-Willem Veening's lab in the Department of Fundamental Microbiology, Biophore Building.
The view is not too bad!
The view is not too bad!
Millie is a cream colored version of our dog Peanut
November 9, 2025 at 11:05 PM
Millie is a cream colored version of our dog Peanut
impact factor is the drug, and we scientists, our institutions, and funding bodies have become addicted
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
November 2, 2025 at 1:49 PM
impact factor is the drug, and we scientists, our institutions, and funding bodies have become addicted
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
DIPPIN' DOTS were never the future but maybe this is
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
November 2, 2025 at 12:16 PM
DIPPIN' DOTS were never the future but maybe this is
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
Great Egret (Ardea alba) in same spot that I saw blue heron last week. These guys are 3 feet tall with 5 foot wingspan but only weigh 2.5 to 3 pounds. Pure biological efficiency. #birds 🪶
November 1, 2025 at 3:20 PM
Great Egret (Ardea alba) in same spot that I saw blue heron last week. These guys are 3 feet tall with 5 foot wingspan but only weigh 2.5 to 3 pounds. Pure biological efficiency. #birds 🪶
very stately coyote I just met on a canyon trail near our home
October 31, 2025 at 1:35 AM
very stately coyote I just met on a canyon trail near our home