Nathan Harmston
@nharmston.bsky.social
Lecturer - Computational biologist. Bit of a muppet. Interested in genome architecture, gene regulation and WNT signalling. Addicted to tea! All views my own
interested in understanding non-coding conservation and genome evolution? I have a PhD position in my group looking at the evolution of regulatory domains in annelids ... www.swbio.ac.uk/files/2025/1... .... 100% computational biology PhD ... e-mail me if you're interested / want to discuss further
www.swbio.ac.uk
November 4, 2025 at 9:39 AM
interested in understanding non-coding conservation and genome evolution? I have a PhD position in my group looking at the evolution of regulatory domains in annelids ... www.swbio.ac.uk/files/2025/1... .... 100% computational biology PhD ... e-mail me if you're interested / want to discuss further
give me aircon or give me death!
August 12, 2025 at 4:43 PM
give me aircon or give me death!
Congrats to Daniel Aron Ang - another great piece of work from his PhD. In this study, he identified that the non-canonical NF-kB factor, p52, can interact with ATF4 to activate oncogenic enhancers through p300/CBP recruitment.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
www.sciencedirect.com
April 17, 2025 at 9:04 PM
Congrats to Daniel Aron Ang - another great piece of work from his PhD. In this study, he identified that the non-canonical NF-kB factor, p52, can interact with ATF4 to activate oncogenic enhancers through p300/CBP recruitment.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Nathan Harmston
A wonderful reminder that my time spent comparing all the ecDNAs in organoids from the @RFitzgerald_lab added new insight to how we can use tumour organoids as a model to study ecDNA.
The future of tumor organoids in precision therapy: Trends in Cancer www.cell.com/trends/cance...
The future of tumor organoids in precision therapy: Trends in Cancer www.cell.com/trends/cance...
The future of tumor organoids in precision therapy
Tumoroids are cultures of patient-derived tumor cells, which are grown in 3D in the
presence of an extracellular matrix extract and specific growth factors. Tumoroids
can be generated from adult as we...
www.cell.com
April 9, 2025 at 2:43 PM
A wonderful reminder that my time spent comparing all the ecDNAs in organoids from the @RFitzgerald_lab added new insight to how we can use tumour organoids as a model to study ecDNA.
The future of tumor organoids in precision therapy: Trends in Cancer www.cell.com/trends/cance...
The future of tumor organoids in precision therapy: Trends in Cancer www.cell.com/trends/cance...
New preprint describing and testing a potential mechanism for how Wnt signalling represses target gene expression ..
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Identification of Wnt regulated genes that are repressed by, or independent of, β-catenin
Wnt signaling regulates metazoan development and homeostasis, in part by β-catenin dependent activation and repression of a large number of genes. However, Wnt signaling also regulates genes independe...
www.biorxiv.org
April 8, 2025 at 6:02 AM
New preprint describing and testing a potential mechanism for how Wnt signalling represses target gene expression ..
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Nathan Harmston
Reposted by Nathan Harmston
Aaron Swartz was surveilled, stopped, indicted and driven to suicide for downloading academic papers to liberate knowledge.
Yet, while the jury is out, model providers must be considered in good faith as they still appropriate copyrighted content for a profit.
Selective application masterpiece.
Yet, while the jury is out, model providers must be considered in good faith as they still appropriate copyrighted content for a profit.
Selective application masterpiece.
"Meta torrented "at least 81.7 terabytes of data across multiple shadow libraries through the site Anna’s Archive, including at least 35.7 terabytes of data from Z-Library and LibGen" arstechnica.com/tech-policy/...
”Torrenting from a corporate laptop doesn’t feel right”: Meta emails unsealed
Meta’s alleged torrenting and seeding of pirated books complicates copyright case.
arstechnica.com
February 7, 2025 at 1:17 AM
Aaron Swartz was surveilled, stopped, indicted and driven to suicide for downloading academic papers to liberate knowledge.
Yet, while the jury is out, model providers must be considered in good faith as they still appropriate copyrighted content for a profit.
Selective application masterpiece.
Yet, while the jury is out, model providers must be considered in good faith as they still appropriate copyrighted content for a profit.
Selective application masterpiece.
YNC moves towards its final days - ending not with a bang but a slow decay into entropy
www.scmp.com/week-asia/ar...
www.scmp.com/week-asia/ar...
‘Everything will be gone’: Singapore’s Yale-NUS closure stirs student ire
With courses changed and faculty departing, students and ex-tutors lament the demise of the city state’s first liberal arts college.
www.scmp.com
January 13, 2025 at 12:40 PM
YNC moves towards its final days - ending not with a bang but a slow decay into entropy
www.scmp.com/week-asia/ar...
www.scmp.com/week-asia/ar...
Reposted by Nathan Harmston
for more information on applying please see - www.findaphd.com/phds/project...
Developing methods for differential mRNA secondary structure analysis at Cardiff University on FindAPhD.com
PhD Project - Developing methods for differential mRNA secondary structure analysis at Cardiff University, listed on FindAPhD.com
www.findaphd.com
November 25, 2024 at 9:57 AM
for more information on applying please see - www.findaphd.com/phds/project...
I currently have a PhD position open through SWBIO DTP to design statistical methods to identify and test for differences between RNA secondary structure using HTS data - bpb-eu-w2.wpmucdn.com/blogs.bristo... ... let me know if it sounds interesting and we can chat. Deadline - Midnight, Wed 11 Dec.
bpb-eu-w2.wpmucdn.com
November 18, 2024 at 10:46 AM
I currently have a PhD position open through SWBIO DTP to design statistical methods to identify and test for differences between RNA secondary structure using HTS data - bpb-eu-w2.wpmucdn.com/blogs.bristo... ... let me know if it sounds interesting and we can chat. Deadline - Midnight, Wed 11 Dec.