Nathaniel Blalock
@nathanielblalock.bsky.social
Graduate Research Assistant in Dr. Philip Romero's Lab at Duke/Wisconsin Reinforcement and Deep Learning for Protein Redesign | He/him
Pinned
We are excited in the @philromero.bsky.social lab to share our new preprint introducing RLXF for the functional alignment of protein language models (pLMs) with experimentally derived notions of biomolecular function!
Reposted by Nathaniel Blalock
Reinforcement learning with experimental feedback (RLXF) shifts protein language models so that they generate sequences with improved properties
@nathanielblalock.bsky.social @philromero.bsky.social
www.biorxiv.org/content/10.1...
@nathanielblalock.bsky.social @philromero.bsky.social
www.biorxiv.org/content/10.1...
May 10, 2025 at 1:46 AM
Reinforcement learning with experimental feedback (RLXF) shifts protein language models so that they generate sequences with improved properties
@nathanielblalock.bsky.social @philromero.bsky.social
www.biorxiv.org/content/10.1...
@nathanielblalock.bsky.social @philromero.bsky.social
www.biorxiv.org/content/10.1...
We are excited in the @philromero.bsky.social lab to share our new preprint introducing RLXF for the functional alignment of protein language models (pLMs) with experimentally derived notions of biomolecular function!
May 8, 2025 at 6:02 PM
We are excited in the @philromero.bsky.social lab to share our new preprint introducing RLXF for the functional alignment of protein language models (pLMs) with experimentally derived notions of biomolecular function!
Great article, simple reminder about the value of higher education! engineering.wisc.edu/blog/why-we-...
Why we do research - College of Engineering - University of Wisconsin-Madison
At a time when the role and value of higher education are being questioned, it's imperative to reflect on the important benefits of research.
engineering.wisc.edu
April 4, 2025 at 3:41 PM
Great article, simple reminder about the value of higher education! engineering.wisc.edu/blog/why-we-...
Reposted by Nathaniel Blalock
🎉Congrats to Chase on her new preprint! She developed OMEGA--a simple method for assembling custom gene panels for as little as $1.50 per gene. Big step forward protein engineering and design!🧬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Scalable and cost-efficient custom gene library assembly from oligopools
Advances in metagenomics, deep learning, and generative protein design have enabled broad in silico exploration of sequence space, but experimental characterization is still constrained by the cost an...
www.biorxiv.org
March 24, 2025 at 4:50 PM
🎉Congrats to Chase on her new preprint! She developed OMEGA--a simple method for assembling custom gene panels for as little as $1.50 per gene. Big step forward protein engineering and design!🧬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Nathaniel Blalock
Post the amazing science things you have done with federal funding.
January 28, 2025 at 8:51 PM
Post the amazing science things you have done with federal funding.
My 1st NeurIPS was a wonderful experience - incredible to see so much research in protein design and reinforcement learning. Here are my favorite papers (and favorite places I got food in Vancouver 😋):
December 20, 2024 at 4:42 PM
My 1st NeurIPS was a wonderful experience - incredible to see so much research in protein design and reinforcement learning. Here are my favorite papers (and favorite places I got food in Vancouver 😋):
Reposted by Nathaniel Blalock
Three BioML starter packs now!
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
December 3, 2024 at 3:27 AM
Three BioML starter packs now!
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)
Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok
DM if you want to be included (or nominate people who should be!)