mspcf
@mspcf.bsky.social
Account run by the lab members of the Mass Spectrometry and Proteomics Core Facility of IRB Barcelona ( @irbbarcelona.org ).
Follow the link to know us!
https://www.irbbarcelona.org/en/research/mass-spectrometry-proteomics
Follow the link to know us!
https://www.irbbarcelona.org/en/research/mass-spectrometry-proteomics
(4/4) #XLMS results support the structural analyses done by Eva’s team, which uncovered how the #GlucocorticoidReceptor (GR) self-assembles into its active forms. This deepens into the understanding of disease-linked GR mutations and establishes a framework for designing selective GR modulators.
November 18, 2025 at 8:36 AM
(4/4) #XLMS results support the structural analyses done by Eva’s team, which uncovered how the #GlucocorticoidReceptor (GR) self-assembles into its active forms. This deepens into the understanding of disease-linked GR mutations and establishes a framework for designing selective GR modulators.
(3/4) We are happy to have contributed by generating the #CrossLinkingMS ( #XLMS ) data and also by using our custom data analysis workflow, which integrates the outputs of different #XLMS software like #MeroX, #xiSEARCH and #XlinkX. @irbbarcelona.org
November 18, 2025 at 8:36 AM
(3/4) We are happy to have contributed by generating the #CrossLinkingMS ( #XLMS ) data and also by using our custom data analysis workflow, which integrates the outputs of different #XLMS software like #MeroX, #xiSEARCH and #XlinkX. @irbbarcelona.org
(2/4) The job, entitled “The multimerization pathway of the glucocorticoid receptor” has been published in @narjournal.bsky.social. Have a look at it!
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
The multimerization pathway of the glucocorticoid receptor
Abstract. The glucocorticoid receptor (GR) is a leading drug target due to its antiinflammatory and immunosuppressive roles. The functional oligomeric conf
academic.oup.com
November 18, 2025 at 8:36 AM
(2/4) The job, entitled “The multimerization pathway of the glucocorticoid receptor” has been published in @narjournal.bsky.social. Have a look at it!
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
(5/5) As a result, the work lead by Frederic and Antònia shed a bit more light on #COX4I1 ( #UniProt link → www.uniprot.org/uniprotkb/P1... ), and its role in #LeighSyndrome, a condition that affects approximately 1 in 40,000 live births.
UniProt
UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.
www.uniprot.org
November 11, 2025 at 10:19 AM
(5/5) As a result, the work lead by Frederic and Antònia shed a bit more light on #COX4I1 ( #UniProt link → www.uniprot.org/uniprotkb/P1... ), and its role in #LeighSyndrome, a condition that affects approximately 1 in 40,000 live births.
(4/5) We contributed by generating the #Proteomics data and by combining our custom data analysis workflow with a supercool tool called #ProtRider (@gagneurlab.bsky.social), which has a strong potential to study #RareDiseases, or any other case in which the number of bioreps available is limited.
November 11, 2025 at 10:19 AM
(4/5) We contributed by generating the #Proteomics data and by combining our custom data analysis workflow with a supercool tool called #ProtRider (@gagneurlab.bsky.social), which has a strong potential to study #RareDiseases, or any other case in which the number of bioreps available is limited.
(3/5) Among these institutions → @hospitalclinic.bsky.social, @idibaps.bsky.social, @isciiisalud.bsky.social, @ub.edu, @irsantpau.bsky.social, Hospital Universitario Cruces, @um.es, @uab.cat and @irbbarcelona.org.
November 11, 2025 at 10:19 AM
(3/5) Among these institutions → @hospitalclinic.bsky.social, @idibaps.bsky.social, @isciiisalud.bsky.social, @ub.edu, @irsantpau.bsky.social, Hospital Universitario Cruces, @um.es, @uab.cat and @irbbarcelona.org.
(2/5) The job, entitled “Complex IV deficiency due to COX4I1 deep intronic and de novo variants results in progressive motor impairment and Leigh syndrome” has been possible thanks to the collaboration of multiple institutions.
November 11, 2025 at 10:19 AM
(2/5) The job, entitled “Complex IV deficiency due to COX4I1 deep intronic and de novo variants results in progressive motor impairment and Leigh syndrome” has been possible thanks to the collaboration of multiple institutions.
(2/2) Many thanks to Amanda Demeter, Fabiana Izaguirre & Guillermo Heins from the #Cellenion team for the great training and support! Still more to come and exciting science ahead… Stay tuned!
#MassSpectrometry #CoreFacilities
#MassSpectrometry #CoreFacilities
October 13, 2025 at 3:04 PM
(2/2) Many thanks to Amanda Demeter, Fabiana Izaguirre & Guillermo Heins from the #Cellenion team for the great training and support! Still more to come and exciting science ahead… Stay tuned!
#MassSpectrometry #CoreFacilities
#MassSpectrometry #CoreFacilities
(2/2) This year’s course was particularly special, as Alba Tomàs carried out her Master’s Project between @ibecbarcelona.eu and our MSPCF at @irbbarcelona.org . She did an outstanding job, focusing on the implementation of new data analysis methods for time-resolved quant #Proteomics. Congrats Alba!
September 10, 2025 at 6:53 PM
(2/2) This year’s course was particularly special, as Alba Tomàs carried out her Master’s Project between @ibecbarcelona.eu and our MSPCF at @irbbarcelona.org . She did an outstanding job, focusing on the implementation of new data analysis methods for time-resolved quant #Proteomics. Congrats Alba!