Modernising Medical Microbiology
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modmedmicro.bsky.social
Modernising Medical Microbiology
@modmedmicro.bsky.social
Modernising Medical Microbiology is a research unit within @ox.ac.uk aiming to transform how we analyse and treat infections, to improve patient care.
These subpopulations also reveal whether resistance arose before or after infection. Our findings show why even small resistant groups matter—and how choosing the wrong antibiotic can help them take over. 💥

#TB #AMR #WAAW #WAAW2025 #AntibioticResistance @oxfordbrc.bsky.social
November 18, 2025 at 6:03 PM
In our study, we investigated how often such resistant minority populations occur in clinical TB samples, focusing on rifampicin (RIF). Including these minorities in resistance profiles significantly improved detection sensitivity. 🧪🔍
November 18, 2025 at 6:03 PM
Resistance testing often yields a single profile per infection. If most bacteria appear susceptible, the antibiotic is used. But this approach fails when a minority, even as little as 5%, are resistant. Those few can survive treatment and take over the infection. ⚔️
November 18, 2025 at 6:03 PM
Reposted by Modernising Medical Microbiology
More evidence to support best practice "water-safe" care in healthcare facilities is urgently needed. If you're interested please tap into the @hisinfection.bsky.social Wastewater and AMR Special Interest Collaborative (SPARC) - see you there!
Wastewater and AMR Special Interest Collaborative (SPARC)
www.his.org.uk
July 26, 2025 at 9:47 AM
Reposted by Modernising Medical Microbiology
Reposted by Modernising Medical Microbiology
This builds on the SinkBug group's earlier work in @thejhi.bsky.social www.journalofhospitalinfection.com/article/S019... where we showed that sink infrastructure in hospitals was common, highly varied, and that antibiotics were detected in a third of sink-traps.
Survey of healthcare-associated sink infrastructure, and sink trap antibiotic residues and biochemistry, in twenty-nine UK hospitals
Hospital sinks are linked to healthcare-associated infections. Antibiotics and chemicals in sink traps can select for pathogens and antimicrobial resistance (AMR). Optimizing sink design and usage can...
www.journalofhospitalinfection.com
July 26, 2025 at 9:47 AM