Sarah Lambert's Lab
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lambertsarahlab.bsky.social
Sarah Lambert's Lab
@lambertsarahlab.bsky.social
Our team investigates the mechanisms ensuring genome maintenance in response to DNA insults and DNA replication failures.
Reposted by Sarah Lambert's Lab
👏 Félicitations au Dr Enzo Poirier, chargé de recherche @inserm.fr et chef d'équipe à l’Institut Curie qui a reçu le prix de la Fondation Joannidès de l'@academiesciences.bsky.social, saluant ses travaux de recherche sur l'immunité innée.
November 26, 2025 at 4:21 PM
Reposted by Sarah Lambert's Lab
I'd also like to highlight a recent publication by @audeber.bsky.social, @enzopoirier.bsky.social, and colleagues showing FAM118B, which they term "SIRal", is essential for innate immune response in mammalian cellular models; they also have great phylogenetic analysis and insights into biochemistry.
A human homolog of SIR2 antiphage proteins mediates immunity via the Toll-like receptor pathway
Key actors of mammalian immunity originated from bacterial antiphage systems. The full extent of immune system conservation between bacteria and eukaryotes is unknown. Here, we show that the silent in...
www.science.org
November 17, 2025 at 2:16 PM