Josh Waitzman
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jwaitz.bsky.social
Josh Waitzman
@jwaitz.bsky.social
Kidney doc, biochemist, and dad, taking life one kinesin-sized step at a time. He/him. Employed by Vertex Pharmaceuticals | BIDMC Nephrology | opinions my own
Tissue is the issue #nephjc
a pink box of soft tissues with flowers on it
ALT: a pink box of soft tissues with flowers on it
media.tenor.com
October 29, 2025 at 1:52 AM
2 years? I think we need a plan for a 2 week update!

Should we have continuously updated recs based on when new evidence comes out? I think NCCN cancer guidelines are like this

#nephjc
October 29, 2025 at 1:51 AM
I have a hard time seeing how we progress from a smorgasbord of individually good therapies to a systematic approach as to which one(s) is (are) best for an individual patient

It’s a good problem but a problem nonetheless

#nephjc
October 29, 2025 at 1:44 AM
I think it we need trials with bi-pronged approaches; it’s tough when no one company (until maybe recently) has therapies in both the immune-modulatory and general nephron preserving camps.

#nephjc
October 29, 2025 at 1:25 AM
Seems like presence/absence of diabetes belongs somewhere in this algorithm?

#nephjc
October 29, 2025 at 1:16 AM
Complement inhibitor had been published on a year before the guidelines were released!

And who knows what’s going to happen at #kidneywk?

Is there a plan for a v2025.2?

#nephjc
October 29, 2025 at 1:14 AM
Really important point here; what is the south Asian representation in trials v real world in IgA? #nephjc
October 29, 2025 at 1:12 AM
Povetacicept! I’m excited to see some new IgA data from everyone at #kidneywk but ApoL1 is still my one true love

#nephjc
October 29, 2025 at 1:07 AM
Josh Waitzman—I work full-time for Vertex and part-time at BIDMC.

COI: Vertex has an ongoing trial of a BAFF/APRIL inhibitor.

Opinions are my own and I only know what’s public.

#nephjc
October 29, 2025 at 1:02 AM
Stoners against kidney stones?
October 13, 2025 at 6:07 PM