Brian Krueger, PhD
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h2so4hurts.bsky.social
Brian Krueger, PhD
@h2so4hurts.bsky.social
Scientific strategist | Storyteller | Genomics, Lab diagnostic and high throughput automation | Coder | Comments are my own | Omic.ly
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I made a feed for all things Omics! Have your posts included in it by adding a 🧬plus any additional omics related emoji🧪🧫🔬🖥️💉🦠🥼. Anything Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, or Metagenomics related (or adjacent!) is welcome!
bsky.app/profile/h2so...
DNA is coded by 4 bases, but no one said that's how we have to sequence it. Ready to have your mind bent? 🧬 🧪
Fuzzy Sequencing: Sometimes close enough is good enough
DNA is coded by 4 bases, but no one said that's how we have to sequence it. Ready to have your mind bent?
www.omic.ly
July 15, 2025 at 5:00 PM
Having trouble sleeping? A new mutation has been discovered that allows people to feel well rested after as little as 4hrs of sleep! 🧬 🧪

www.omic.ly/a-gene-for-s...
A gene for short sleep duration
Having trouble sleeping? A new mutation has been discovered that allows people to feel well rested after as little as 4hrs of sleep!
www.omic.ly
May 20, 2025 at 2:03 PM
The most famous photo in the history of genetics wasn’t generated by Watson and Crick, but that didn’t stop them from using it to solve the structure of DNA. 🧬 🧪 #histSci

www.omic.ly/the-most-fam...
The most famous picture in the history of genetics
The most famous photo in the history of genetics wasn’t generated by Watson and Crick, but that didn’t stop them from using it to solve the structure of DNA.
www.omic.ly
May 17, 2025 at 3:00 PM
Mass Spec is leading the charge in bringing high-throughput proteomics to a lab near you. 🧬 🧪

www.omic.ly/mass-spec-is...
Mass spec is primed to lead the next proteomics revolution
Mass Spec is leading the charge in bringing high-throughput proteomics to a lab near you.
www.omic.ly
May 15, 2025 at 3:01 PM
There’s more to de novo mutations (DNMs) than just SNPs and indels. 🧬 🧪

www.omic.ly/de-novo-muta...
De novo mutations are more common than we previously thought
There’s more to de novo mutations (DNMs) than just SNPs and indels.
www.omic.ly
May 13, 2025 at 3:03 PM
Multiplex aptamer/antibody arrays are a gateway drug to get genetics people to embrace proteomics. 🧬 🧪
www.omic.ly/how-to-do-pr...
How to do proteomics using a high throughput sequencer
Multiplex aptamer/antibody arrays are a gateway drug to get genetics people to embrace proteomics.
www.omic.ly
May 1, 2025 at 5:00 PM
Approximately 2,000 people die every year waiting for a liver transplant. Pigs might help change that! 🧬 🧪

www.omic.ly/a-pig-liver-...
A pig liver makes its way into a human
Approximately 2,000 people die every year waiting for a liver transplant. Pigs might help change that!
www.omic.ly
April 29, 2025 at 3:04 PM
High throughput proteomics could revolutionize our understanding of human disease, but it's going to take some major innovations to get us there! 🧬 🧪

www.omic.ly/the-future-o...
The future of high throughput proteomics is unfolding right in front of us
High throughput proteomics could revolutionize our understanding of human disease, but it's going to take some major innovations to get us there!
www.omic.ly
April 24, 2025 at 3:01 PM
Ultima Genomics is put to the test in MRD 🧬 🧪

www.omic.ly/will-ultimas...
Will Ultima's ultra cheap bases be a major boon to MRD?
Ultima Genomics is put to the test in MRD
www.omic.ly
April 22, 2025 at 3:00 PM
Derek Lowe telling it like it is: No, AI isn't going to cure all disease
www.science.org/content/blog...
The End of Disease
www.science.org
April 21, 2025 at 9:22 PM
In 1994, an obscure jellyfish protein was stuck into a worm. It has enlightened biology and medicine ever since. 🧬 🧪 #HistSci

www.omic.ly/jelly-fish-p...
Jelly fish proteins started brightening up microscopy in 1994
In 1994, an obscure jellyfish protein was stuck into a worm. It has enlightened biology and medicine ever since.
www.omic.ly
April 18, 2025 at 3:01 PM
I made a feed for all things Omics! Have your posts included in it by adding a 🧬plus any additional omics related emoji🧪🧫🔬🖥️💉🦠🥼. Anything Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, or Metagenomics related (or adjacent!) is welcome!
bsky.app/profile/h2so...
April 18, 2025 at 1:02 PM
The importance of taking out the trash: An overview of cellular protein degradation pathways. 🧬 🧪

www.omic.ly/the-proteaso...
The proteasome and lysosome decide what proteins live or die
The importance of taking out the trash: An overview of cellular protein degradation pathways.
www.omic.ly
April 17, 2025 at 3:00 PM
HOT TAKE: Dire wolves are still very much extinct, Illumina is dumping its smallest sequencer, and PacBio finally sees the light

www.omic.ly/de-extincted...
De-extincted" Dire Wolves, A Discontinued Sequencer, and PacBio Goes Long
HOT TAKE: Dire wolves are still very much extinct, Illumina is dumping its smallest sequencer, and PacBio finally sees the light
www.omic.ly
April 16, 2025 at 3:02 PM
Deep brain structures play a key role in filtering out what we perceive 🧬 🧪

www.omic.ly/how-does-the...
How does the brain control perception of everything around us?
Deep brain structures play a key role in filtering out what we perceive
www.omic.ly
April 15, 2025 at 3:02 PM
Definitely a miracle of modern science.
No vaccine hesitancy here. Dropped by @krogerpharmacy.bsky.social for my first doses of shingles and pneumonia vaccines. Don't let anyone tell you they aren't modern miracles. Wonders of molecular biology. 🧪🧬🔬💉
April 14, 2025 at 10:56 PM
Maybe we should just learn to not believe tech bros when they pretend to know science?

cen.acs.org/biological-c...
Dire wolf debate raises concerns on scientific overhype
Even de-extinction advocates say that Colossal Biosciences’ claims are misleading
cen.acs.org
April 12, 2025 at 3:25 PM
The Lac Operon showed us that gene expression can be regulated 🧬 🧪 #histsci
The Lac Operon showed us that gene expression can be regulated
'If gene expression determines the function of a cell, it must be important to control that process?' Yes, very! Let me tell you about the PaJaMo experiment.
www.omic.ly
April 11, 2025 at 5:02 PM
Translating the Proteome: There’s more to making proteins than just transcribing DNA into mRNA. 🧬 🧪
Translation complicates the proteome, big time!
Translating the Proteome: There’s more to making proteins than just transcribing DNA into mRNA.
www.omic.ly
April 10, 2025 at 3:02 PM
In a development that should surprise no one, population scale exome screening finds actionable variants. 🧬 🧪
Sequencing exomes in healthy populations pays dividends
In a development that should surprise no one, population scale exome screening finds actionable variants.
www.omic.ly
April 9, 2025 at 3:02 PM
April 7, 2025 at 11:36 PM
Horseshoe crab blood is our first line of defense against endotoxin contamination of surgical tools and medical devices. Seriously. 🧬 🧪
Horseshoe crab blood to the rescue!
Horseshoe crab blood is our first line of defense against endotoxin contamination of surgical tools and medical devices. Seriously.
www.omic.ly
April 4, 2025 at 3:00 PM
Proteoforms: This is where things start to get complicated. 🧬 🧪
Proteoforms make proteomics infinitely more complicated than genomics
Proteoforms: This is where things start to get complicated.
www.omic.ly
April 3, 2025 at 5:01 PM