Gabriele Zaffagnini
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gzaffagnini.bsky.social
Gabriele Zaffagnini
@gzaffagnini.bsky.social
870 followers 1.7K following 110 posts
Group Leader at CECAD, University of Cologne.
Interested in reproductive aging, protein homeostasis in oocytes, and super-organelles.
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gzaffagnini.bsky.social
The #cellbio2025 is starting this week! I’ll be giving a talk on the first 1st day, in the session organized by @iaincheeseman.bsky.social and @abbybuch.bsky.social (Thx for the invitation!). If you’re interested in #oocytes, #proteostasis, and #aging come by to attend! @ascbiology.bsky.social
December 1, 2025 at 8:29 AM
gzaffagnini.bsky.social
Happy Sunday egg-ficionados! Here comes the latest issue of #cebooc, full of Christmas atmosphere and great papers!

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41308649/ by @yanivelkouby.bsky.social

Thanks @biomednews.bsky.social for preselecting!
November 30, 2025 at 8:32 AM
gzaffagnini.bsky.social
Ho ho ho, happy Sunday egg-ficionados! Here is another great issue of #cebooc: biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41241715/
Runner-up: pubmed.ncbi.nlm.nih.gov/41271398/

Thanks @biomednews.bsky.social for preselecting!
November 23, 2025 at 8:01 AM
gzaffagnini.bsky.social
It's Sunday again and a new issue of #cebooc is out!
biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41223274/ on the maternal #mitochondria selection

Runner-up: pubmed.ncbi.nlm.nih.gov/41210958/

Thanks @biomednews.bsky.social for preselecting!
November 16, 2025 at 8:27 AM
gzaffagnini.bsky.social
What an egg-cellent Sunday for oocyte papers! This week we have even TWO highlights:

pubmed.ncbi.nlm.nih.gov/41188464/ by T. Kitajima

and pubmed.ncbi.nlm.nih.gov/41184483/ by @binyammogessie.bsky.social

Read the full issue here: biomed.news/bims-cebooc/...

#cebooc
@biomednews.bsky.social
November 9, 2025 at 9:24 AM
gzaffagnini.bsky.social
Happy Sunday egg-ficionados! Here comes a new issue of #cebooc!

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41173887/ on the role of mechanical forces in ovarian follicles development.

As always, thanks to @biomednews.bsky.social for preselecting!
November 2, 2025 at 8:41 AM
gzaffagnini.bsky.social
Happy Sunday ovo-lovers! A new issue of #cebooc is here!

biomed.news/bims-cebooc/...

This week 2 stunning highlights: pubmed.ncbi.nlm.nih.gov/41129643/ and pubmed.ncbi.nlm.nih.gov/41131150/

Thanks @biomednews.bsky.social for preselecting!
October 26, 2025 at 8:04 AM
gzaffagnini.bsky.social
Happy Sunday egg-ficionados! The latest issue of #Cebooc is here!

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41102564/

Thanks @biomednews.bsky.social for preselecting!
October 19, 2025 at 8:23 AM
gzaffagnini.bsky.social
Happy Sunday!! Ready for a new spectacular issue of #cebooc?👇🏽

biomed.news/bims-cebooc/...

Highlight: PMID 41066539 on the comparison between human and mouse ovarian aging

Special mention to PMID 41066576 by @frisophagy.bsky.social on mitochondrial selection by mitophagy in the early embryo
October 12, 2025 at 6:41 AM
gzaffagnini.bsky.social
Happy Sunday egg-ficionados! Here come the latest papers on #oocyte cell biology:

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41027914/

Thanks @biomednews.bsky.social for preselecting! #cebooc
October 5, 2025 at 8:08 AM
gzaffagnini.bsky.social
Happy Autumn! Here comes a very rich issue of #cebooc, read all the latest #papers on oocyte cell #biology here:

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/40993317/

Kudos to @biomednews.bsky.social for preselecting!
September 28, 2025 at 7:40 AM
gzaffagnini.bsky.social
It was great to attend and give a talk at the Groningen-Jena Aging Meeting (G-JAM)! Very nice conference in a great historical location! Thanks a lot to the organisers @mariaermolaeva.bsky.social and Alessandro Cellerino for the invitation! @leibnizfli.bsky.social @uni-jena.de
September 26, 2025 at 11:02 AM
gzaffagnini.bsky.social
Happy Sunday! Ready for the latest papers on #oocyte cell biology?

Here they come! biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/40973727/ by @abalboula.bsky.social and @ejsm9.bsky.social

Thanks @biomednews.bsky.social for preselecting!
September 21, 2025 at 7:25 AM
gzaffagnini.bsky.social
Happy Sunday! Here is a new issue of #cebooc, featuring the latest papers on #oocyte cell biology, enjoy!

biomed.news/bims-cebooc/...

Thanks to @biomednews.bsky.social for preselecting!
September 14, 2025 at 9:28 AM
gzaffagnini.bsky.social
Happy Monday eggficionados, #cebooc is back! Ready for a new year of exciting papers on oocyte cell biology? Start now! 👇🏽

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/40902605/

Thanks @biomednews.bsky.social for preselecting
September 8, 2025 at 6:52 AM
gzaffagnini.bsky.social
Here we go again! Our paper on #proteostasis in human oocytes appeared on the latest @embojournal.org cover! A great collaboration with Dexeus Mujer @bokelab.bsky.social ! 🥂👏🏻💪🏻
August 18, 2025 at 12:35 PM
gzaffagnini.bsky.social
Happy Sunday! Here is today's issue of #cebooc with the latest papers on #oocyte biology!

biomed.news/bims-cebooc/...

Highlight: PMID 40803772 by @idajentoft.bsky.social @schuhlab.bsky.social in @annualreviews.bsky.social

Powered by @biomednews.bsky.social

PS: #cebooc goes on 🏖️, cu in Sept!
August 17, 2025 at 7:06 AM
gzaffagnini.bsky.social
Happy Sunday! Here is another great issue of #cebooc, bringing to you the latest papers on #oocyte cell biology!

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/40768572/ on how human oocytes don't accumulate mtDNA mutations with age.

powered by @biomednews.bsky.social.
August 10, 2025 at 7:33 AM
gzaffagnini.bsky.social
Happy August egg-ficionados! Enjoy this spectacular issue of #cebooc with a lot of useful methods papers!

biomed.news/bims-cebooc/...

Highlight: Iterative oocyte immunofluorescence by
@adelaljord.bsky.social, super useful! pubmed.ncbi.nlm.nih.gov/40736799/

Powered by
@biomednews.bsky.social
August 3, 2025 at 9:31 AM
gzaffagnini.bsky.social
Happy Sunday! A new issue of #cebooc is here, check it out!

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/40696105/ on the metabolic regulation of embryogenesis

Thanks @biomednews.bsky.social for preselecting!
July 27, 2025 at 8:19 AM
gzaffagnini.bsky.social
Happy Sunday egg-ficionados! Don't miss today's golden issue of #cebooc, the manually curated list of papers on #oocyte cell biology!

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/40664214/ by @takashiakeralab.bsky.social

Thanks @biomednews.bsky.social for preselecting!
July 20, 2025 at 7:31 AM
gzaffagnini.bsky.social
Overall, our study provides a reference for future research on #aged oocytes and from #infertility #patients. With our previous work, our results further highlight how oocytes from different mammalian species adopt different strategies to regulate #proteostasis during their extended #life.

9/
July 16, 2025 at 11:36 AM
gzaffagnini.bsky.social
And what about protein #aggregates? While mouse oocytes store them in large endolysosomal vesicular asseblies (ELVAs), human oocytes seem to sequester them inside individual enlarged lysosomes (similar to what some quiescent stem cells do).

8/
July 16, 2025 at 11:36 AM
gzaffagnini.bsky.social
In most MIIs, mitochondria also start to surround clusters of ER membranes below the cell cortex. Another super-organelle awaiting to be studied maybe?? 🤩

7/
July 16, 2025 at 11:36 AM
gzaffagnini.bsky.social
We also found that organelles undergo a dramatic redistribution from GVs to MIIs: while #lysosomes undergo exocytosis, as highlighted by the appearance of LAMP1 on the cell surface, #mitochondria spread throughout the cytoplasm

6/
July 16, 2025 at 11:36 AM