Graydon Hoare
graydon-pub.bsky.social
Graydon Hoare
@graydon-pub.bsky.social
extremely dubious of "everything is public" social network
I do not believe a word of anything from the US administration. Tylenol was in the news and I took the opportunity to remind people it's Actually Dangerous. To wit: hundreds of thousands of people wind up in hospital annually, and thousands die. My father among them. I was not "dooped" about that.
September 24, 2025 at 7:31 PM
agreed
September 24, 2025 at 7:22 PM
great, cool, I'll tell that to the hundreds of thousands of hospitalizations and thousands of accidental deaths every year (including my father).
September 24, 2025 at 7:22 PM
I mentioned it because (a) I was experiencing a flood of people saying it's a super safe med and (b) it literally killed my father.

sorry this doesn't fit your beat-timing preferences. I tried hard to make it clear I was not saying anything at all about pregnancy.
September 24, 2025 at 7:20 PM
like ibuprofen can cause stomach bleeds, and if your health status puts you at risk of those, ibuprofen can be a terrible and even deadly choice too. a lot of drugs used very casually have serious caveats about dosing or interactions. that's all I meant to point out. a fact often learned too late.
September 24, 2025 at 8:02 AM
yeah not trying to speak to pregnancy at all. pregnancy is dangerous in a lot of dimensions; from a quick literature search it seems the consensus (narrow) safest path for pregnancy actually _is_ tylenol. I was speaking more generally, like "consider other nsaids if they're safe for your situation."
September 24, 2025 at 7:56 AM
Reposted by Graydon Hoare
"Clean Indoor air is a gap in our public health frameworks. We need to close that gap."
September 23, 2025 at 8:28 PM
like your Erdős number but backwards
September 23, 2025 at 10:04 PM
I guess there's this line people draw between condemning people's actions vs. inherent nature, a person's redeemability, guilt-vs-shame, etc. Sure, whatever. But like if your whole life's work is to embody a given moral project, is it doing a lot to split that particular hair?
September 23, 2025 at 9:49 PM
Reposted by Graydon Hoare
At this point I have seen so many people with medical tragedies that at long last boil down to either "mis-dosed drug" or "drug side effect" or "drug interaction" that it's now the first thing I ask about when discussing health issues. "Do you by any chance have some medication you take regularly?"
September 23, 2025 at 8:32 PM
At this point I have seen so many people with medical tragedies that at long last boil down to either "mis-dosed drug" or "drug side effect" or "drug interaction" that it's now the first thing I ask about when discussing health issues. "Do you by any chance have some medication you take regularly?"
September 23, 2025 at 8:32 PM
Yeah exactly. It's like decades of mom and apple pie marketing makes everyone think it's totally harmless. Which it mostly is, right up until it suddenly kills you.
September 23, 2025 at 8:28 PM
(Or see also my other friend who also nearly lost their liver because they had a strenuous and painful manual labour job and would often down a beer and a tylenol in the same couple hours after work. People just do not know! It is like taking a restorative nap on a railroad track.)
September 23, 2025 at 8:27 PM
Also key fact if you happen to have an ageing boomer parent who likes an occasional drink in the evenings and maybe also has some arthritis: alcohol in your blood makes the effects on the liver dramatically higher.
September 23, 2025 at 8:21 PM
np! I would be thrilled if it was generally understood as having A Strict Limit everywhere. I like healthy livers.
September 23, 2025 at 8:19 PM
yes exactly. you can't fix a failed liver. you get a transplant or more likely you just die.
September 23, 2025 at 8:12 PM
i'm not a pharmacist but my experience is that the general public is deeply unaware of the consequences of exceeding standard dosage, and take it like pain-relief candy rather than potentially liver shredding power tool.
September 23, 2025 at 8:11 PM
I mean, personal tragedy time: tylenol killed my dad. Everyone thinks this is a fairly harmless drug to take a lot of and it absolutely is not. Sorry! Please don't involve pregnant people or autistic people in this story though. Just internalize en.wikipedia.org/wiki/Paracet... and pick safer drugs.
Paracetamol poisoning - Wikipedia
en.wikipedia.org
September 23, 2025 at 8:06 PM
US .. envoy .. to Syria!
September 23, 2025 at 7:55 PM