Sir William Dunn School, University of Oxford, Interested in genome stability, homologous recombination, chromosome, centromeres https://esashilab.wordpress.com/
This study, conceived eight years ago, was made possible by a global collaboration across the UK, USA, Japan and Turkey. The dedicated team efforts of Emily and Lucia, relayed by Brian, Jacob, Emoke and Ramazan, and invaluable assistance from many others, brought this research to life.
February 25, 2025 at 5:56 PM
This study, conceived eight years ago, was made possible by a global collaboration across the UK, USA, Japan and Turkey. The dedicated team efforts of Emily and Lucia, relayed by Brian, Jacob, Emoke and Ramazan, and invaluable assistance from many others, brought this research to life.
Note that the phenotype varies between cell lines (HCT116 vs RPE1), but in the big picture, we propose that homologous recombination and mismatch repair factors engage in a ‘tug of war’ at centromeres to maintain their functional resilience.
February 25, 2025 at 5:56 PM
Note that the phenotype varies between cell lines (HCT116 vs RPE1), but in the big picture, we propose that homologous recombination and mismatch repair factors engage in a ‘tug of war’ at centromeres to maintain their functional resilience.