<em>Developmental Dynamics</em> is a developmental biology journal publishing novel discoveries that advance our understanding in development, morphology, evolution, and disease.

Tau pathology is increasingly recognized as a primary driver of white matter (WM) microstructural damage in tauopathies, particularly in Alzheimer's d…

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Degeneration of myelinating oligodendrocytes and the resulting breakdown of the myelin sheath are key drivers of neurodegeneration and disability across numerous central nervous system pathologies. Thus, a compelling strategy to preserve neuronal function is to promote endogenous myelin repair by oligodendrocyte precursor cells (OPCs). Extracellular vesicles (EVs) secreted by pro-regenerative microglia have been shown to enhance OPC maturation and remyelination across different experimental m...

A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.

Aspettarsi che una persona rimanga razionale quando è spaventata e confusa non è - appunto - per nulla razionale. Ed è in quei momenti che il rischio di cadere in un baratro di farmaci miracolosi e cu...

The brain is ready. It luxuriated in a solution of potassium bicarbonate for a year, and then in a thick mixture of nitrocellulose for another month and a half, and now it is finally ripe for the slic...

Park, Nicaise, Tsitsipatis, and colleagues discover transcriptional and epigenetic markers in human PMS iNSCs and fibroblasts that may underlie their senescent and inflammatory state. Novel DARGs with...

Myelin pathology in demyelinating diseases is accompanied by lipid remodeling that remains challenging to characterize at spatial level using traditio…