Eikan Mishima
@eikan-em.bsky.social
#Ferroptosis #HelmholtzMunich #TohokuUniv
We report a short commentary in @pnas.org highlighting that the MALT1 inhibitor MI-2 also inhibits GPX4—an off-target effect to consider in #ferroptosis studies.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
MALT1 inhibitor MI-2 induces ferroptosis by direct targeting of GPX4 | PNAS
MALT1 inhibitor MI-2 induces ferroptosis by direct targeting of GPX4
www.pnas.org
May 12, 2025 at 6:32 AM
We report a short commentary in @pnas.org highlighting that the MALT1 inhibitor MI-2 also inhibits GPX4—an off-target effect to consider in #ferroptosis studies.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Eikan Mishima
Keystone “Lipids in Cellular Function and Disease” is off to a terrific start with an awesome Keynote lecture from Marcus Conrad on #Ferroptosis! #KSLipids25 👏
April 7, 2025 at 10:25 PM
Keystone “Lipids in Cellular Function and Disease” is off to a terrific start with an awesome Keynote lecture from Marcus Conrad on #Ferroptosis! #KSLipids25 👏
Reposted by Eikan Mishima
👇
Important walkthrough for newcomers in the field
rdcu.be/eg58p
rdcu.be/eg58p
Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology - Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in...
rdcu.be
April 14, 2025 at 10:01 AM
👇
Reposted by Eikan Mishima
ICYMI: New Online! Recommendations for robust and reproducible research on ferroptosis
Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology, Published online: 09 April 2025; doi:10.1038/s41580-025-00843-2Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in disease. This Expert Recommendation article summarizes ferroptosis regulation and mechanisms and provides recommendations to increase the reproducibility and robustness of ferroptosis research.
bit.ly
April 12, 2025 at 8:03 PM
ICYMI: New Online! Recommendations for robust and reproducible research on ferroptosis
Reposted by Eikan Mishima
Important considerations while studying ferroptosis. A great starting point for anyone entering this field.
Important walkthrough for newcomers in the field
rdcu.be/eg58p
rdcu.be/eg58p
Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology - Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in...
rdcu.be
April 10, 2025 at 8:22 AM
Important considerations while studying ferroptosis. A great starting point for anyone entering this field.
Reposted by Eikan Mishima
New Online! Recommendations for robust and reproducible research on ferroptosis
Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology, Published online: 09 April 2025; doi:10.1038/s41580-025-00843-2Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in disease. This Expert Recommendation article summarizes ferroptosis regulation and mechanisms and provides recommendations to increase the reproducibility and robustness of ferroptosis research.
bit.ly
April 9, 2025 at 8:02 PM
New Online! Recommendations for robust and reproducible research on ferroptosis
Happy to share our new review on recommendations for #ferroptosis research, now out in NatRevMCB!
We cover recommended experimental models, tools, and common pitfalls in the field. Hope this will be a helpful resource for both new and experienced ferroptosis researchers.
rdcu.be/eg58p
We cover recommended experimental models, tools, and common pitfalls in the field. Hope this will be a helpful resource for both new and experienced ferroptosis researchers.
rdcu.be/eg58p
Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology - Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in...
rdcu.be
April 10, 2025 at 7:26 PM
Happy to share our new review on recommendations for #ferroptosis research, now out in NatRevMCB!
We cover recommended experimental models, tools, and common pitfalls in the field. Hope this will be a helpful resource for both new and experienced ferroptosis researchers.
rdcu.be/eg58p
We cover recommended experimental models, tools, and common pitfalls in the field. Hope this will be a helpful resource for both new and experienced ferroptosis researchers.
rdcu.be/eg58p
Happy to share our design was selected as cover art
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
December 6, 2024 at 6:17 AM
Happy to share our design was selected as cover art
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
in MolecularCell🎉
This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
Reposted by Eikan Mishima
PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization 🧪
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
Ito et al. highlight peroxiredoxin 6 (PRDX6) as a critical regulator of ferroptosis.
As a selenium-acceptor protein, PRDX6 aids in intracellular selenium utilization for
efficient selenoprotein biosyn...
www.cell.com
November 14, 2024 at 4:56 PM
PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization 🧪
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
🎉Excited to share our new paper – identifying PRDX6 as a key regulator of #ferroptosis, acting as a selenium-carrier protein. Now online in Mol Cell.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
Ito et al. highlight peroxiredoxin 6 (PRDX6) as a critical regulator of ferroptosis.
As a selenium-acceptor protein, PRDX6 aids in intracellular selenium utilization for
efficient selenoprotein biosyn...
www.cell.com
November 15, 2024 at 9:06 AM
🎉Excited to share our new paper – identifying PRDX6 as a key regulator of #ferroptosis, acting as a selenium-carrier protein. Now online in Mol Cell.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...