Edward J Schenck
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edschenck.bsky.social
Edward J Schenck
@edschenck.bsky.social
Clinical translational pccm researcher. Love methods, history and learning more about how to practice medicine.
I’m really struggling to understand how we can assess the validity of ITE models. C for benefit requires some strong assumptions. Does anyone have a critical review?
January 13, 2025 at 4:55 PM
Reposted by Edward J Schenck
🦠We call a lot of things “sepsis”

🔎Our #AnnalsofIM study examined how broad this grab bag really is

⚠️Among ~75,000 patients with sepsis, we found remarkably wide spectrum of presentations & outcomes across infection source & organ dysfunction patterns

Thread ⬇️
#medsky #emimcc #idsky #pharmsky
December 17, 2024 at 4:08 PM
Reposted by Edward J Schenck
This Christmas, 5years on from the publication of the ICH E9 Addendum on #Estimands @suziecro.bsky.social & I describe a fictitious, festive #RCT conducted by Santa to answer the question: does a reindeer’s pre-flight meal impact performance? #trials #clinicaltrials link.springer.com/article/10.1...
All I want for Christmas…is a precisely defined research question - Trials
link.springer.com
December 16, 2024 at 7:59 AM