Protein structures are not inherently robust, but natural proteins are substantially more robust than random sequences, representing a clear signature of adaptation. Mutational robustness is relatively low in newborn and viral proteins, and provides a new perspective on protein evolution.

RNA structures are inherently evolvable and robust to mutations: random RNA molecules already show the same level of robustness and a similar distribution of secondary structures as natural RNA molecules. Hence, it is difficult to detect signatures of selection on the distribution of RNA structures.

We have found before, including in different models, that evolutionary conflict leads to better adaptive solutions. These challenges best expose the creativity of evolutionary processes. Or, borrowing from Nietzsche: "What doesn't kill you makes you stronger" (at the population level)!

Our main finding: Mixing of endosymbionts (sex) is dangerous but can stimulate beneficial regulatory integration of host and symbiont!

In our study, we found that genome organization emerges, in which the positions of regulatory genes along the chromosome correlate with their temporal activity during the cell cycle...

I would really appreciate a wide sharing of this post, as the candidate profile I am looking for is outside of my regular circle. Thank you so much. More info and how to apply here: uu.varbi.com/se/what:job/... (2/2)

Hope that helps?