Cecilia Zaza
@ceciliazaza.bsky.social
Physicist from 🇦🇷 interested in single molecule localization microscopy. HFSP fellow at Simoncelli's lab at UCL, London. (She/her)
👏Congrats to the whole team! Megan D. Joseph, Olivia LP Dalby, Rhian Walther, Karol Kołątaj, German Chiarelli, @fpichaud.bsky.social, Guillermo Acuna and Sabrina Simoncelli.
Special thanks to @healthcare.nikon.com and @lmcb-ucl.bsky.social Imaging facility for their support.
Special thanks to @healthcare.nikon.com and @lmcb-ucl.bsky.social Imaging facility for their support.
May 30, 2025 at 3:17 PM
👏Congrats to the whole team! Megan D. Joseph, Olivia LP Dalby, Rhian Walther, Karol Kołątaj, German Chiarelli, @fpichaud.bsky.social, Guillermo Acuna and Sabrina Simoncelli.
Special thanks to @healthcare.nikon.com and @lmcb-ucl.bsky.social Imaging facility for their support.
Special thanks to @healthcare.nikon.com and @lmcb-ucl.bsky.social Imaging facility for their support.
🔬 We believe this advancement will unlock new biological questions at scales and resolutions previously unattainable.
🧬 What systems would you explore with this level of detail?
🧬 What systems would you explore with this level of detail?
May 30, 2025 at 3:14 PM
🔬 We believe this advancement will unlock new biological questions at scales and resolutions previously unattainable.
🧬 What systems would you explore with this level of detail?
🧬 What systems would you explore with this level of detail?
✨ And yes—we go 3D.
We achieve:
✅ sub-10 nm localization precision at 9 μm depth in whole cells 🦠
✅ ~12 nm precision in complex tissues (like the Drosophila eye 👁)
Think about that: near-molecular detail, deep inside tissues.
We achieve:
✅ sub-10 nm localization precision at 9 μm depth in whole cells 🦠
✅ ~12 nm precision in complex tissues (like the Drosophila eye 👁)
Think about that: near-molecular detail, deep inside tissues.
May 30, 2025 at 3:13 PM
✨ And yes—we go 3D.
We achieve:
✅ sub-10 nm localization precision at 9 μm depth in whole cells 🦠
✅ ~12 nm precision in complex tissues (like the Drosophila eye 👁)
Think about that: near-molecular detail, deep inside tissues.
We achieve:
✅ sub-10 nm localization precision at 9 μm depth in whole cells 🦠
✅ ~12 nm precision in complex tissues (like the Drosophila eye 👁)
Think about that: near-molecular detail, deep inside tissues.
✨ We push further:
🌈 Multicolour imaging and 🎯 #RESI = repetitive imaging → ultra-high resolution.
This opens complex multiplexed experiments inside cells, where precision matters.
🌈 Multicolour imaging and 🎯 #RESI = repetitive imaging → ultra-high resolution.
This opens complex multiplexed experiments inside cells, where precision matters.
May 30, 2025 at 3:12 PM
✨ We push further:
🌈 Multicolour imaging and 🎯 #RESI = repetitive imaging → ultra-high resolution.
This opens complex multiplexed experiments inside cells, where precision matters.
🌈 Multicolour imaging and 🎯 #RESI = repetitive imaging → ultra-high resolution.
This opens complex multiplexed experiments inside cells, where precision matters.
✅ On a commercial microscope, we achieve sub-10 nm resolution on DNA origami across a 76 x76 μm2 field of view!
✅ We apply this in cells to resolve nuclear pore complex protein pairs inside the cellular context.
This is true protein-level imaging, across large scales.
✅ We apply this in cells to resolve nuclear pore complex protein pairs inside the cellular context.
This is true protein-level imaging, across large scales.
May 30, 2025 at 3:11 PM
✅ On a commercial microscope, we achieve sub-10 nm resolution on DNA origami across a 76 x76 μm2 field of view!
✅ We apply this in cells to resolve nuclear pore complex protein pairs inside the cellular context.
This is true protein-level imaging, across large scales.
✅ We apply this in cells to resolve nuclear pore complex protein pairs inside the cellular context.
This is true protein-level imaging, across large scales.