bioRxiv Genetics
@biorxiv-genetic.bsky.social
Brain-wide Genome Editing via STEP-RNPs for Treatment of Angelman Syndrome https://www.biorxiv.org/content/10.1101/2025.11.13.684643v1
November 14, 2025 at 4:00 PM
Brain-wide Genome Editing via STEP-RNPs for Treatment of Angelman Syndrome https://www.biorxiv.org/content/10.1101/2025.11.13.684643v1
PRISM: ancestry-aware integration of tissue-specific genomic annotations enhances the transferability of polygenic scores https://www.biorxiv.org/content/10.1101/2025.11.13.688144v1
November 14, 2025 at 8:31 AM
PRISM: ancestry-aware integration of tissue-specific genomic annotations enhances the transferability of polygenic scores https://www.biorxiv.org/content/10.1101/2025.11.13.688144v1
Sequence context and methylation interact to shape germline mutation rate variation at CpG sites https://www.biorxiv.org/content/10.1101/2025.11.13.688199v1
November 14, 2025 at 4:32 AM
Sequence context and methylation interact to shape germline mutation rate variation at CpG sites https://www.biorxiv.org/content/10.1101/2025.11.13.688199v1
Signaling by RasG12V depends on EGFR activity in vivo https://www.biorxiv.org/content/10.1101/2025.11.12.687982v1
November 13, 2025 at 5:33 PM
Signaling by RasG12V depends on EGFR activity in vivo https://www.biorxiv.org/content/10.1101/2025.11.12.687982v1
Characterization of Endogenous and Epitope-Tagged Ubiquitin Expression and Ubiquitination Patterns at Drosophila Neuromuscular Junctions https://www.biorxiv.org/content/10.1101/2025.11.11.687520v1
November 13, 2025 at 3:31 PM
Characterization of Endogenous and Epitope-Tagged Ubiquitin Expression and Ubiquitination Patterns at Drosophila Neuromuscular Junctions https://www.biorxiv.org/content/10.1101/2025.11.11.687520v1
Environmental DNA monitoring of waterfowl reveals community changes during migration https://www.biorxiv.org/content/10.1101/2025.11.11.687912v1
November 13, 2025 at 3:30 PM
Environmental DNA monitoring of waterfowl reveals community changes during migration https://www.biorxiv.org/content/10.1101/2025.11.11.687912v1
Selection History Models in a Population under Ongoing Directional Selection https://www.biorxiv.org/content/10.1101/2025.11.11.687909v1
November 13, 2025 at 7:33 AM
Selection History Models in a Population under Ongoing Directional Selection https://www.biorxiv.org/content/10.1101/2025.11.11.687909v1
High-efficiency targeted integration of extrachromosomal arrays in C. elegans using PhiC31 integrase https://www.biorxiv.org/content/10.1101/2025.11.11.687718v1
November 13, 2025 at 2:32 AM
High-efficiency targeted integration of extrachromosomal arrays in C. elegans using PhiC31 integrase https://www.biorxiv.org/content/10.1101/2025.11.11.687718v1
Machine Learning Identifies Common Risk Variants and Implicates Abnormal Vision Physiology in ASD https://www.biorxiv.org/content/10.1101/2025.11.11.687806v1
November 12, 2025 at 10:32 PM
Machine Learning Identifies Common Risk Variants and Implicates Abnormal Vision Physiology in ASD https://www.biorxiv.org/content/10.1101/2025.11.11.687806v1
Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics https://www.biorxiv.org/content/10.1101/2025.11.10.687605v1
November 12, 2025 at 12:33 AM
Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics https://www.biorxiv.org/content/10.1101/2025.11.10.687605v1
Tobacco twin and single spots result from genome instability, chromosome breaks, and translocations https://www.biorxiv.org/content/10.1101/2025.11.09.687472v1
November 11, 2025 at 3:35 AM
Tobacco twin and single spots result from genome instability, chromosome breaks, and translocations https://www.biorxiv.org/content/10.1101/2025.11.09.687472v1
Metagenomes and Metagenome-Assembled Genomes from Microbial Communities in a Biological Nutrient Removal Plant Operated at Los Angeles County Sanitation District (LACSD) with High and Low Dissolved Oxygen Conditions https://www.biorxiv.org/content/10.1101/2025.11.10.687646v1
November 11, 2025 at 3:35 AM
Metagenomes and Metagenome-Assembled Genomes from Microbial Communities in a Biological Nutrient Removal Plant Operated at Los Angeles County Sanitation District (LACSD) with High and Low Dissolved Oxygen Conditions https://www.biorxiv.org/content/10.1101/2025.11.10.687646v1
Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression https://www.biorxiv.org/content/10.1101/2025.11.10.687584v1
November 11, 2025 at 2:33 AM
Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression https://www.biorxiv.org/content/10.1101/2025.11.10.687584v1
Enhancing Intra-Continental Biogeographical Ancestry Prediction Through a Machine Learning Marker Selection Method https://www.biorxiv.org/content/10.1101/2025.11.08.687358v1
November 10, 2025 at 9:36 PM
Enhancing Intra-Continental Biogeographical Ancestry Prediction Through a Machine Learning Marker Selection Method https://www.biorxiv.org/content/10.1101/2025.11.08.687358v1
Staphylococcus haemolyticus Population Genomics Provides Insights into Pathogenicity and Commensalism https://www.biorxiv.org/content/10.1101/2025.11.08.687178v1
November 10, 2025 at 9:36 PM
Staphylococcus haemolyticus Population Genomics Provides Insights into Pathogenicity and Commensalism https://www.biorxiv.org/content/10.1101/2025.11.08.687178v1
Recapitulating the length polymorphism of RS3, a composite microsatellite implicated in human social behavior, via recombination in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.1101/2025.11.09.687482v1
November 10, 2025 at 9:36 PM
Recapitulating the length polymorphism of RS3, a composite microsatellite implicated in human social behavior, via recombination in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.1101/2025.11.09.687482v1
Gene expression profiling for forensic age assessment of porcine skin wounds https://www.biorxiv.org/content/10.1101/2025.11.06.686914v1
November 10, 2025 at 1:35 PM
Gene expression profiling for forensic age assessment of porcine skin wounds https://www.biorxiv.org/content/10.1101/2025.11.06.686914v1
Assessing fish diversity in the Amazon: The impact of primers and reference libraries in eDNA surveys https://www.biorxiv.org/content/10.1101/2025.11.07.686145v1
November 9, 2025 at 2:32 AM
Assessing fish diversity in the Amazon: The impact of primers and reference libraries in eDNA surveys https://www.biorxiv.org/content/10.1101/2025.11.07.686145v1
Integrating Longitudinal Metabolite Profiles Improves Trait Prediction in Pigs in a Trait- and Timepoint-Dependent Manner https://www.biorxiv.org/content/10.1101/2025.11.06.687040v1
November 8, 2025 at 12:32 PM
Integrating Longitudinal Metabolite Profiles Improves Trait Prediction in Pigs in a Trait- and Timepoint-Dependent Manner https://www.biorxiv.org/content/10.1101/2025.11.06.687040v1
Post-admixture selection favours Duffy negativity in the Lower Okavango Basin https://www.biorxiv.org/content/10.1101/2025.11.06.687002v1
November 8, 2025 at 3:33 AM
Post-admixture selection favours Duffy negativity in the Lower Okavango Basin https://www.biorxiv.org/content/10.1101/2025.11.06.687002v1
Phage-Plasmids Are Rare in Bacteria, May Exhibit Pseudolysogeny and Lack Antibiotic Resistance Genes https://www.biorxiv.org/content/10.1101/2025.11.07.687105v1
November 8, 2025 at 3:33 AM
Phage-Plasmids Are Rare in Bacteria, May Exhibit Pseudolysogeny and Lack Antibiotic Resistance Genes https://www.biorxiv.org/content/10.1101/2025.11.07.687105v1
Systematic comparison of colocalization methods using protein quantitative trait loci https://www.biorxiv.org/content/10.1101/2025.11.07.686776v1
November 8, 2025 at 3:33 AM
Systematic comparison of colocalization methods using protein quantitative trait loci https://www.biorxiv.org/content/10.1101/2025.11.07.686776v1
Safeguarding Genome Integrity: Polo-like kinase Cdc5 and phosphatase Cdc14 Orchestrate Topoisomerase II-Mediated Catenane Resolution in Mitosis https://www.biorxiv.org/content/10.1101/2025.11.06.686928v1
November 7, 2025 at 11:32 PM
Safeguarding Genome Integrity: Polo-like kinase Cdc5 and phosphatase Cdc14 Orchestrate Topoisomerase II-Mediated Catenane Resolution in Mitosis https://www.biorxiv.org/content/10.1101/2025.11.06.686928v1
Genotype-level quality control substantially reduces error rates in population-scale whole-genome sequencing https://www.biorxiv.org/content/10.1101/2025.11.06.686913v1
November 7, 2025 at 10:33 PM
Genotype-level quality control substantially reduces error rates in population-scale whole-genome sequencing https://www.biorxiv.org/content/10.1101/2025.11.06.686913v1
Insect Identification with ESEM Imaging and DNA Barcoding for Forensic Use https://www.biorxiv.org/content/10.1101/2025.11.05.686861v1
November 7, 2025 at 5:34 PM
Insect Identification with ESEM Imaging and DNA Barcoding for Forensic Use https://www.biorxiv.org/content/10.1101/2025.11.05.686861v1