Ana Raquel Cruz
anaraquelcruz.bsky.social
Ana Raquel Cruz
@anaraquelcruz.bsky.social
Postdoctoral researcher at @karinaxavierlab.bsky.social. Interested in host-microbiota interactions.
Reposted by Ana Raquel Cruz
All this and many more changes you can find in the published version here - in my (biased) opinion, it is worth a re-read even if you have seen the preprint!
www.nature.com/articles/s41...

And of course, all was only possible thanks to our great collaboration with @mizrahilab.bsky.social

(4/4)
Spatial constraints drive amylosome-mediated resistant starch degradation by Ruminococcus bromii in the human colon - Nature Communications
Here, combining structural, proteomics and biochemical analyses, the authors elucidate how the keystone gut bacterium Ruminococcus bromii assembles a specialized enzyme complex, the amylosome, to effi...
www.nature.com
December 1, 2025 at 7:45 PM
Reposted by Ana Raquel Cruz
Very excited to share our latest work in Science on metagenomic editing (MetaEdit) of the gut microbiome in vivo & directly modifying unculturable immune-modulatory SFB bug in the small intestine. 🦠🧬🛠️
www.science.org/doi/10.1126/...
Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases
Although metagenomic sequencing has revealed a rich microbial biodiversity in the mammalian gut, methods to genetically alter specific species in the microbiome are highly limited. Here, we introduce ...
www.science.org
November 13, 2025 at 8:53 PM