Aditi Merchant
adititm.bsky.social
Aditi Merchant
@adititm.bsky.social
BioE PhD student @ Stanford in the Hie Lab // ML for Synthetic Biology
Together, this work suggests that genomic sequence models can meaningfully generalize beyond characterized natural evolution. Looking forward, we hope that semantic design can serve as a starting point for function-guided design and optimization of genes across biology.
November 19, 2025 at 4:37 PM
What if we could autocomplete DNA based on function?

Today in @Nature, we share semantic design—a strategy for function-guided design with genomic language models that leverages genomic context to create de novo genes and systems with desired functions. 🧵

www.nature.com/articles/s41...
November 19, 2025 at 4:31 PM