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ignaciogbravo.bsky.social
Ignacio G. Bravo
@ignaciogbravo.bsky.social
82 followers 46 following 8 posts

Interested in life, mechanisms and evolution across integration levels, and in the social and philosophical dimensions of science. Scientist at the CNRS in Montpellier, opinions are my own.

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Biology 40%
Public Health 34%
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ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 31
Instructive et nuancée, la sociologue Eve Seguin @themeta.news, sur le décisionnisme "à la base duquel se trouve l’idée que la volonté politique prime sur l’ordre constitutionnel". Des parallèles avec l'imposition des "lignes directrices" et #keylabs @cnrs.bsky.social

themeta.news/limage-publi...
« L'image publique d'une science unifiée doit être abandonnée» — TheMetaNews
Comment analysez-vous la récente réélection de Donald Trump ? Si l’on s’écarte de la science un instant, l’analyse que je fais en tant que politologue est la suivante : on considère souvent Donald Tru...
themeta.news
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ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 30
Forecasts on death toll in European cities because of increasing temperatures. Anything below parallel 44, and especially the Mediterranean arch, will suffer.
More data won't convince any sceptics, though.

www.nature.com/articles/s41...
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ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 22
Just published! We show that eukaryotic ribosomes can handle bicistronic mRNAs by leaky scanning. Efficiency depends on codon usage and splicing on the upstream ORF. This helps understand non-canonical translation from polycistronic viral mRNAs.
onlinelibrary.wiley.com/doi/10.1002/...
Translation of the downstream ORF from bicistronic mRNAs by human cells: Impact of codon usage and splicing in the upstream ORF
Biochemistry textbooks describe eukaryotic mRNAs as monocistronic. However, increasing evidence reveals the widespread presence and translation of upstream open reading frames preceding the “main” OR...
onlinelibrary.wiley.com
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ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 15
On the importance of being (biologically) faithful. We show in this preprint that there exists an equilibrium in the #noise and fidelity levels in information transfer in biology, that depends on the environment, #populationsize and #genotypetophenotype mapping.

www.biorxiv.org/content/10.1...
The Population Genetics of Biological Noise
Noise is intrinsic to information transmission, and information transmission is intrinsic to life. Critically, while biological noise is random, its amount is in part genetically determined. Here, we ...
www.biorxiv.org
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ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 13
"Can a biologist fix a radio?" A (to me) hidden gem that reminds me that some of my conceptual and experimental approaches in biochemistry, mol bio and cell bio may hamper rather than help for understanding life.

www.cell.com/cancer-cell/...
Can a biologist fix a radio?—Or, what I learned while studying apoptosis
As a freshly minted Assistant Professor, I feared that everything in my field would be discovered before I even had a chance to set up my laboratory. Indeed, the field of apoptosis, which I had recent...
www.cell.com
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ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 8
Post en français. Le nouveau ministre chargé de l’Enseignement supérieur et de la Recherche, Philippe BAPTISTE, se réclame chercheur et fait sa déclaration d'intentions. La musique est bonne. On attend les paroles. Merci @themeta.news pour le texte complet.
themeta.news/wp-content/u...
themeta.news
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ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 7
Post en español. Entretenida (y hermosa!) divulgación de la #teoríadejuegos aplicada a la #evolución por Alejandro Couce.
elpais.com/ciencia/cafe...
Las matemáticas que explican por qué retirarse a tiempo es una victoria
John Maynard Smith revolucionó el estudio de la evolución y del comportamiento animal aplicando la teoría de juegos a los sistemas dinámicos. Sus ideas se usan en múltiples problemas en economía, filo...
elpais.com

ignaciogbravo.bsky.social
Ignacio G. Bravo @ignaciogbravo.bsky.social · Jan 5
Hello, Bluesky world

happy to join the community and discuss about the evolution of viruses, infections and cancer, information transfer in biology, and about the Russian-doll structure of life, from molecules to cells to tissues, to individuals, to communities.

Cheers!
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Reposted by Ignacio G. Bravo

luisapallares.bsky.social
Luisa F. Pallares @luisapallares.bsky.social · Dec 12
(3/3) Check out details here pallareslab.github.io/bionoise2025... - We have only 40 spots, so register soon! @smbmathbiology.bsky.social
SMBE Satellite Meeting Biological Noise
SMBE Satellite Meeting Biological Noise
pallareslab.github.io
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Reposted by Ignacio G. Bravo

luisapallares.bsky.social
Luisa F. Pallares @luisapallares.bsky.social · Dec 12
(2/3) Come to Tübingen to discuss this with us! We are hosting an SMBE Satellite Meeting on the 'Origin, Maintenance, and Evolution of Biological Noise' in June 2025. Co-organizers: Julien Dutheil, Nacho Bravo, and Dan Weinreich.
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Reposted by Ignacio G. Bravo, Dominique C. Bergmann

luisapallares.bsky.social
Luisa F. Pallares @luisapallares.bsky.social · Dec 12
(1/3) Ever wonder if there is anything in common between people studying #plasticity, #variability, #robustness, #bethedging, #variance, error-prone #molecularmechanisms? Might we all be thinking about different manifestations of Biological Noise? @official-smbe.bsky.social @mpi-bio-fml.bsky.social
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