Author | Lightnews

TRAIL4Life @trail4l.bsky.social · 9d

Participants not only learned about the science of breathing but also experienced practical exercises guided by Prof. Saatçıoğlu.
A big thank you to Prof. Saatçıoğlu for sharing his knowledge and energy, and to everyone who joined us for this engaging and refreshing session!💫

TRAIL4Life @trail4l.bsky.social · 9d

As #CHIRONProject, we successfully completed an inspiring session with Prof. Fahri Saatçıoğlu from the University of Oslo, as part of the Teaching & Training Series in cooperation with IBG & RareBoost.

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TRAIL4Life @trail4l.bsky.social · 10d

The team’s regular happy hour provided a pleasant chance to welcome Maria to the lab.
We’re looking forward to many fruitful discussions and joint discoveries ahead.

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TRAIL4Life @trail4l.bsky.social · 10d

✨We’re delighted to welcome Maria Despoina Liassa (from e-NIOS) to the Wingender Lab at IBG as part of her secondment within the #CHIRONProject!
It’s a pleasure to have her join the team and share her expertise and enthusiasm.

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TRAIL4Life @trail4l.bsky.social · 13d

Dr. Wingender: "Thanks so much for this opportunity and the stimulating scientific exchange. I also greatly enjoyed the French snacks during the breaks."🌟
#INSERM #CTM #IBG #HorizonEurope

TRAIL4Life @trail4l.bsky.social · 13d

During his visit to our partner Dr. Micheau (INSERM, Dijon, France), Dr. Wingender (IBG, Izmir, Turkey) had the opportunity to introduce our #CHIRONProject and IBG's contribution to it at CTM's annual scientific meeting (3.10.25) of the Center for Translational and Molecular Medicine (CTM, Dijon).

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TRAIL4Life @trail4l.bsky.social · 18d

As part of the Teaching & Training Series in cooperation with IBG & RareBoost, join Prof. Fahri Saatçıoğlu (University of Oslo) for The Science of Breath – Practical Knowledge for Health and Wellness, exploring breathing techniques to boost health and wellbeing.

TRAIL4Life @trail4l.bsky.social · 19d

A glimpse from our project partners in Athens💫
Discussing the circuitry of immune cell subtypes in cancer on a rainy Athenian day. Fantastic to see this collaboration in motion!
#CHIRONProject #ResearchCollaboration #Science #ScientificPartnership

TRAIL4Life @trail4l.bsky.social · 26d

#CHIRONProject #BudapestUniversityofTechnologyandEconomics #GALWAY #research

TRAIL4Life @trail4l.bsky.social · 26d

I definitely benefited not only professionally but also personally from the refreshing, diverse and extremely friendly environment in the lab. On weekends, I was happy to move around and get to know the Irish culture and the beauty of Western Ireland. I'm looking forward to going back soon!"

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TRAIL4Life @trail4l.bsky.social · 26d

The experience of our secondee János Máté Orosz (BME):

"Over the course of my one-month secondment at the University of Galway, Ireland, I had the opportunity to gain valuable knowledge in cell biology (cell culture and in vitro cytotoxicity measurements) under the supervision of Eva Szegezdi.

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TRAIL4Life @trail4l.bsky.social · Oct 1

Joined by Dr. Gerhard Wingender, Ana Luiza Seidinger and Pumla Manyatsi, everyone left the table strengthened and recharged after a good meal.

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TRAIL4Life @trail4l.bsky.social · Oct 1

After a long day of insightful discussions on bioinformatic approaches to deciphering the role of TRAIL/DRs in the tumour microenvironment with #CHIRONProject partner Dr. Eleftherios Pilalis (eNIOS, Greece), the #IBG team rounded off the evening with a delightful dinner by the Izmir bay.

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TRAIL4Life @trail4l.bsky.social · Sep 24

#UBERN #ResearchCollaboration #LifeSciences #Bioinformatics #AcademicCollaboration

TRAIL4Life @trail4l.bsky.social · Sep 24

Our partner, Dr. Philippe Krebs from the University of Bern (Switzerland), arrived at e-NIOS (Athens, Greece) to advance #CHIRONProject's collaboration with our partners, Dr. Aristotelis Chatziioannou and Dr. Eleftherios Pilalis, and the rest of the team.
We are excited about the progress ahead🌟

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TRAIL4Life @trail4l.bsky.social · Sep 3

#ResearchCollaboration #HorizonEurope #CancerResearch #CellBiology #DrugResistance #SingleCellAnalysis

TRAIL4Life @trail4l.bsky.social · Sep 3

Javid will work on developing an assay for single-cell metabolic characterization of tumor cells, aiming to better understand the mechanisms behind drug resistance.

Looking forward to seeing the exciting results of their projects!

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TRAIL4Life @trail4l.bsky.social · Sep 3

Wanshan’s project will focus on uncovering the apical signal mediators of TRAIL-induced migration using MDA-MB-231 cells deficient in DR5 DISC complex components, as well as DR4-DR5 chimeric receptors, to identify the DR5 domains responsible for triggering migratory signaling.

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TRAIL4Life @trail4l.bsky.social · Sep 3

✨We are glad to see #CHIRONProject secondees Javid and Wanshan from #Galway starting their two-month secondment at #INSERM Dijon, where they will work under the supervision of Olivier Micheau.

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TRAIL4Life @trail4l.bsky.social · Jul 31

Only if we understand the impact of TRAIL on immune cells can effective TRAIL-based anti-cancer therapies be developed.

#CancerResearch #Immunology #TRAIL

TRAIL4Life @trail4l.bsky.social · Jul 31

to spread to the lungs. Furthermore, these TRAIL+ blood vesicles were better at predicting lung metastasis than current clinical markers.
This study provides another interesting example of how TRAIL can influence the immune system, something the #CHIRONProject consortium is investigating as well.

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TRAIL4Life @trail4l.bsky.social · Jul 31

When tumour cells run low on sugar, they get stressed and release vesicles coated with the death ligand TRAIL. Travelling to the lungs, these vesicles altered the function of lung macrophages via TRAIL, which then suppressed lung NK cells. This suppression made it easier for primary tumour cells+

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TRAIL4Life @trail4l.bsky.social · Jul 31

🚨New study alert

Rapidly dividing tumours need lots of energy; therefore, restricting access to sugar, e.g. via the diet, can curb the growth of primary tumours. Surprisingly, however, a new study noted that this can increase the frequency of lung metastases.
www.cell.com/cell/abstrac...

Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

While targeting glucose metabolism shows potential in cancer therapy, its clinical implications remain unclear. This study finds that low-carbohydrate diets or impaired glucose metabolism in cancer ce...

www.cell.com

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TRAIL4Life @trail4l.bsky.social · Jul 30

Dr. Tutku Yaraş's presentation “Decoding Bioinformatics Visualizations: A practical guide to understand common scientific figures” is now available on our YouTube channel.
www.youtube.com/watch?v=3ZTj...

#seminar #research #science #bioinformatics

Decoding Bioinformatics Visualizations: A practical guide to understand common scientific figures

YouTube video by TRAIL4Life

www.youtube.com

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TRAIL4Life @trail4l.bsky.social · Jul 22

#CancerResearch #TargetedTherapy #DrugDevelopment #DeathReceptors #ColorectalCancer #TumorTargeting #CollaborativeResearch